3NI5
Carbonic anhydrase inhibitor: C1 family
Summary for 3NI5
Entry DOI | 10.2210/pdb3ni5/pdb |
Related | 3NJ9 |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase, inhibitors, sulfonamide, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30036.54 |
Authors | Temperini, C.,Cecchi, A.,Scozzafava, A.,Supuran, C.T. (deposition date: 2010-06-15, release date: 2011-06-22, Last modification date: 2023-11-01) |
Primary citation | Mincione, F.,Benedini, F.,Biondi, S.,Cecchi, A.,Temperini, C.,Formicola, G.,Pacileo, I.,Scozzafava, A.,Masini, E.,Supuran, C.T. Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action Bioorg.Med.Chem.Lett., 21:3216-3221, 2011 Cited by PubMed: 21549597DOI: 10.1016/j.bmcl.2011.04.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report