6UT2
 
 | | 3D structure of the leiomodin/tropomyosin binding interface | | 分子名称: | Leiomodin-2, Tropomyosin alpha-1 chain chimeric peptide | | 著者 | Tolkatchev, D, Smith, G.E, Helms, G.L, Cort, J.R, Kostyukova, A.S. | | 登録日 | 2019-10-29 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Leiomodin creates a leaky cap at the pointed end of actin-thin filaments.
Plos Biol., 18, 2020
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6XZ3
 | | Crystal structure of TLNRD1 4-helix bundle | | 分子名称: | 1,2-ETHANEDIOL, Talin rod domain-containing protein 1 | | 著者 | Cowell, A, Singh, A.K, Brown, D.G, Goult, B.T. | | 登録日 | 2020-02-01 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Talin rod domain-containing protein 1 (TLNRD1) is a novel actin-bundling protein which promotes filopodia formation.
J.Cell Biol., 220, 2021
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6XZ4
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7ZAU
 | | Fascin-1 in complex with Nb 3E11 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ... | | 著者 | Burgess, S.G, Bayliss, R. | | 登録日 | 2022-03-22 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation.
Open Biology, 14, 2024
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5I2L
 | | Structure of EF-hand containing protein | | 分子名称: | CALCIUM ION, EF-hand domain-containing protein D2 | | 著者 | Park, K.R, Kwon, M.S, An, J.Y, Lee, J.G, Youn, H.S, Lee, Y, Kang, J.Y, Kim, T.G, Lim, J.J, Park, J.S, Lee, S.H, Song, W.K, Cheong, H, Jun, C, Eom, S.H. | | 登録日 | 2016-02-09 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural implications of Ca(2+)-dependent actin-bundling function of human EFhd2/Swiprosin-1.
Sci Rep, 6, 2016
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5LE0
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3TPO
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1AOA
 | | N-TERMINAL ACTIN-CROSSLINKING DOMAIN FROM HUMAN FIMBRIN | | 分子名称: | T-FIMBRIN | | 著者 | Goldsmith, S.C, Pokala, N, Shen, W, Fedorov, A.A, Matsudaira, P, Almo, S.C. | | 登録日 | 1997-06-30 | | 公開日 | 1997-12-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structure of an actin-crosslinking domain from human fimbrin.
Nat.Struct.Biol., 4, 1997
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1QQV
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6V62
 | | SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine | | 分子名称: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | | 著者 | Dai, S, Horton, J.R, Cheng, X. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
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6V63
 | | SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Actin, ... | | 著者 | Dai, S, Horton, J.R, Cheng, X. | | 登録日 | 2019-12-04 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
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7NVL
 | | Human TRiC complex in closed state with nanobody bound (Consensus Map) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC) | | 登録日 | 2021-03-15 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
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7NVN
 | | Human TRiC complex in closed state with nanobody and tubulin bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W. | | 登録日 | 2021-03-15 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
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7NVO
 | | Human TRiC complex in open state with nanobody bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W. | | 登録日 | 2021-03-15 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
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6WK1
 | | SETD3 in Complex with an Actin Peptide with His73 Replaced with Methionine | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Actin, ... | | 著者 | Dai, S, Horton, J.R, Cheng, X. | | 登録日 | 2020-04-15 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
J.Biol.Chem., 295, 2020
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7NZM
 | | Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Yan, Y, Hardwick, S, Ron, D. | | 登録日 | 2021-03-24 | | 公開日 | 2021-09-29 | | 最終更新日 | 2021-10-20 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Nat.Struct.Mol.Biol., 28, 2021
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6WK2
 | | SETD3 mutant (N255V) in Complex with an Actin Peptide with His73 Replaced with Methionine | | 分子名称: | 1,2-ETHANEDIOL, Actin, cytoplasmic 2, ... | | 著者 | Dai, S, Horton, J.R, Cheng, X. | | 登録日 | 2020-04-15 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
J.Biol.Chem., 295, 2020
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5NL6
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5JOL
 | | Calcium-free EF-hand domain of L-plastin | | 分子名称: | Plastin-2 | | 著者 | Ishida, H, Jensen, K.V, Woodman, A.G, Hyndman, M.E, Vogel, H.J. | | 登録日 | 2016-05-02 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling.
Sci Rep, 7, 2017
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5JOJ
 | | Calcium-loaded EF-hand domain of L-plastin | | 分子名称: | CALCIUM ION, Plastin-2 | | 著者 | Ishida, H, Jensen, K.V, Woodman, G.W, Hyndman, M.E, Vogel, H.J. | | 登録日 | 2016-05-02 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling.
Sci Rep, 7, 2017
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8EFE
 | | Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Beta-cardiac myosin II, MAGNESIUM ION, ... | | 著者 | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | | 登録日 | 2022-09-08 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin.
J.Gen.Physiol., 155, 2023
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8EFD
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5JCY
 | | Spir2-GTBM bound to MyoVa-GTD | | 分子名称: | Protein spire homolog 2, Unconventional myosin-Va | | 著者 | Pylypenko, O, Malherbes, G, Welz, T, Kerkhoff, E, Houdusse, A. | | 登録日 | 2016-04-15 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.
Elife, 5, 2016
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7NXV
 | | Crystal structure of the complex of DNase I/G-actin/PPP1R15A_582-621 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Yan, Y, Ron, D. | | 登録日 | 2021-03-19 | | 公開日 | 2021-09-29 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Nat.Struct.Mol.Biol., 28, 2021
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4FML
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