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7RK9
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BU of 7rk9 by Molmil
Cryo-EM Structure of Adeno-Associated Virus Serotype 1 with Engineered Peptide Domain PHP.B (AAV1-PHP.B)
分子名称: Capsid protein
著者Fluck, E.C, Pumroy, R.A, Moiseenkova-Bell, V.Y.
登録日2021-07-22
公開日2021-08-04
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.32 Å)
主引用文献Context-Specific Function of the Engineered Peptide Domain of PHP.B.
J.Virol., 95, 2021
6K2Y
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BU of 6k2y by Molmil
Human Galectin-14
分子名称: Placental protein 13-like
著者Su, J.
登録日2019-05-15
公開日2020-06-17
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structure-function studies of galectin-14, an important effector molecule in embryology.
Febs J., 288, 2021
3QLU
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BU of 3qlu by Molmil
Crystal structure of the GluK2/GluK5 (GluR6/KA2) ATD dimer assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Kumar, J, Mayer, M.L.
登録日2011-02-03
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Structure and assembly mechanism for heteromeric kainate receptors.
Neuron, 71, 2011
3QLT
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BU of 3qlt by Molmil
Crystal structure of a GluK2 (GluR6) glycan wedge homodimer assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor, ionotropic kainate 2
著者Kumar, J, Mayer, M.L.
登録日2011-02-03
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.988 Å)
主引用文献Structure and assembly mechanism for heteromeric kainate receptors.
Neuron, 71, 2011
3OLZ
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BU of 3olz by Molmil
Crystal structure of the GluK3 (GluR7) ATD dimer at 2.75 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate receptor, ...
著者Kumar, J, Mayer, M.L.
登録日2010-08-26
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains.
J.Mol.Biol., 404, 2010
4V8M
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BU of 4v8m by Molmil
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ...
著者Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J.
登録日2012-12-09
公開日2014-07-09
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.57 Å)
主引用文献High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
8SCB
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BU of 8scb by Molmil
Terminating ribosome with SRI-41315
分子名称: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ...
著者Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S.
登録日2023-04-05
公開日2023-12-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Nat.Chem.Biol., 20, 2024
8R6F
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BU of 8r6f by Molmil
CryoEM structure of wheat 40S ribosomal subunit, body domain
分子名称: 30S ribosomal protein S11, chloroplastic, 30S ribosomal protein S4, ...
著者Kravchenko, O.V, Baymukhametov, T.N, Afonina, Z.A, Vasilenko, K.S.
登録日2023-11-22
公開日2023-12-27
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献High-Resolution Structure and Internal Mobility of a Plant 40S Ribosomal Subunit.
Int J Mol Sci, 24, 2023
3FB4
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BU of 3fb4 by Molmil
Crystal structure of adenylate kinase from Marinibacillus marinus
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION
著者Davlieva, M.G, Shamoo, Y.
登録日2008-11-18
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and biochemical characterization of an adenylate kinase originating from the psychrophilic organism Marinibacillus marinus.
Acta Crystallogr.,Sect.F, 65, 2009
1VAX
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BU of 1vax by Molmil
Crystal Structure of Uricase from Arthrobacter globiformis
分子名称: Uric acid oxidase
著者Hossain, M.T, Suzuki, K, Yamamoto, T, Imamura, S, Sekiguchi, T, Takenaka, A.
登録日2004-02-19
公開日2005-06-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal Structure of Uricase from Arthrobacter globiformis
To be Published
7YSJ
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BU of 7ysj by Molmil
GluK1-1a in nanodisc captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-12
公開日2023-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
6YV7
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Mannosyltransferase PcManGT from Pyrobaculum calidifontis
分子名称: Glycosyl transferase, family 2
著者Divne, C, Rosaria, G.
登録日2020-04-28
公開日2020-07-22
最終更新日2020-08-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
8DMB
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BU of 8dmb by Molmil
Structure of Desulfovirgula thermocuniculi IsrB (DtIsrB) in complex with omega RNA and target DNA
分子名称: MAGNESIUM ION, Ubiquitin-like protein SMT3,IsrB protein,monomeric superfolder Green Fluorescent Protein, non-target DNA, ...
著者Seiichi, H, Kappel, K, Zhang, F.
登録日2022-07-08
公開日2022-10-19
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the OMEGA nickase IsrB in complex with omega RNA and target DNA.
Nature, 610, 2022
6YV9
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BU of 6yv9 by Molmil
Mannosyltransferase PcManGT from Pyrobaculum calidifontis in complex with GDP-Man and Mn2+
分子名称: GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, Glycosyl transferase, family 2, ...
著者Divne, C, Gandini, R.
登録日2020-04-28
公開日2020-07-22
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold.
J.Mol.Biol., 432, 2020
5H7H
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BU of 5h7h by Molmil
Crystal structure of the BCL6 BTB domain in complex with F1324(10-13)
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, F1324 peptide residues 10-13
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017
5H8O
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BU of 5h8o by Molmil
Crystal structure of an ASC-binding nanobody in complex with the CARD domain of ASC
分子名称: Apoptosis-associated speck-like protein containing a CARD, VHH nanobody
著者Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L.
登録日2015-12-23
公開日2016-04-06
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (4.206 Å)
主引用文献A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
5H7G
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BU of 5h7g by Molmil
Crystal structure of the BCL6 BTB domain in complex with F1324
分子名称: B-cell lymphoma 6 protein, F1324 peptide, SULFATE ION
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017
5H8D
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BU of 5h8d by Molmil
Crystal structure of an ASC binding nanobody
分子名称: VHH nanobody
著者Lu, A, Schmidt, F.I, Ruan, J, Tang, C, Wu, H, Ploegh, H.L.
登録日2015-12-23
公開日2016-04-06
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
6EI3
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BU of 6ei3 by Molmil
Crystal structure of auto inhibited POT family peptide transporter
分子名称: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, Proton-dependent oligopeptide transporter family protein
著者Newstead, S, Brinth, A, Vogeley, L, Caffrey, M.
登録日2017-09-17
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Proton movement and coupling in the POT family of peptide transporters.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6F62
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BU of 6f62 by Molmil
Crystal structure of the SYCP1 N-terminal head-to-head assembly in open conformation
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Synaptonemal complex protein 1
著者Dunce, J.M, Davies, O.R.
登録日2017-12-04
公開日2018-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.066 Å)
主引用文献Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Nat. Struct. Mol. Biol., 25, 2018
6F64
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Crystal structure of the SYCP1 C-terminal back-to-back assembly
分子名称: ACETATE ION, Synaptonemal complex protein 1
著者Dunce, J.M, Millan, C, Uson, I, Davies, O.R.
登録日2017-12-04
公開日2018-06-06
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Nat. Struct. Mol. Biol., 25, 2018
6F5X
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BU of 6f5x by Molmil
Crystal structure of the SYCP1 N-terminal head-to-head assembly in closed conformation
分子名称: IODIDE ION, Synaptonemal complex protein 1, TRIETHYLENE GLYCOL
著者Ratcliff, M, Dunce, J.M, Davies, O.R.
登録日2017-12-04
公開日2018-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly.
Nat. Struct. Mol. Biol., 25, 2018
7TGR
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BU of 7tgr by Molmil
Structure of SARS-CoV-2 main protease in complex with GC376
分子名称: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 1,2-ETHANEDIOL, ...
著者Esler, M.A, Shi, K, Aihara, H, Harris, R.S.
登録日2022-01-09
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells.
Mbio, 13, 2022
4JQ7
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Crystal structure of EGFR kinase domain in complex with compound 2a
分子名称: (2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol, Epidermal growth factor receptor
著者Peng, Y.H, Wu, J.S.
登録日2013-03-20
公開日2013-06-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors
J.Med.Chem., 56, 2013
4JRV
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Crystal structure of EGFR kinase domain in complex with compound 4c
分子名称: 4-(dimethylamino)-N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]butanamide, Epidermal growth factor receptor
著者Peng, Y.H, Wu, J.S.
登録日2013-03-22
公開日2013-06-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors
J.Med.Chem., 56, 2013

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