6RLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rlp by Molmil](/molmil-images/mine/6rlp) | |
4MM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mm1 by Molmil](/molmil-images/mine/4mm1) | GGGPS from Methanothermobacter thermautotrophicus | 分子名称: | Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL | 著者 | Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | 登録日 | 2013-09-07 | 公開日 | 2014-06-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8004 Å) | 主引用文献 | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
|
|
7MXP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mxp by Molmil](/molmil-images/mine/7mxp) | Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)][beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Reddem, E.R, Casner, R.G, Shapiro, L. | 登録日 | 2021-05-19 | 公開日 | 2022-05-25 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | 主引用文献 | Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2. Aiche J, 67, 2021
|
|
6F2K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f2k by Molmil](/molmil-images/mine/6f2k) | Crystal structure of Hen Egg-White Lysozyme co-crystallized in presence of 100 mM Tb-Xo4 and 100 mM potassium phosphate monobasic. | 分子名称: | CHLORIDE ION, Lysozyme C, TERBIUM(III) ION | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
|
|
6ASO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6aso by Molmil](/molmil-images/mine/6aso) | Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | 著者 | Montemayor, E.J, Brow, D.A, Butcher, S.E. | 登録日 | 2017-08-25 | 公開日 | 2018-05-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
|
|
5C4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c4g by Molmil](/molmil-images/mine/5c4g) | |
6PLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6plr by Molmil](/molmil-images/mine/6plr) | CryoEM structure of zebra fish alpha-1 glycine receptor bound with glycine in nanodisc, desensitized state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor subunit alphaZ1, ... | 著者 | Yu, J, Zhu, H, Gouaux, E. | 登録日 | 2019-07-01 | 公開日 | 2021-01-06 | 最終更新日 | 2021-07-21 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor. Cell, 184, 2021
|
|
6F5U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f5u by Molmil](/molmil-images/mine/6f5u) | CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH BEPRIDIL | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bepridil, DIMETHYL SULFOXIDE, ... | 著者 | Ren, J, Zhao, Y, Fry, E.E, Stuart, D.I. | 登録日 | 2017-12-03 | 公開日 | 2018-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection. J. Med. Chem., 61, 2018
|
|
5FQD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fqd by Molmil](/molmil-images/mine/5fqd) | Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase | 分子名称: | CASEIN KINASE I ISOFORM ALPHA, DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, ... | 著者 | Petzold, G, Fischer, E.S, Thoma, N.H. | 登録日 | 2015-12-09 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase. Nature, 532, 2016
|
|
5MF2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mf2 by Molmil](/molmil-images/mine/5mf2) | Bacteriophage T5 distal tail protein pb9 co-crystallized with Tb-Xo4 | 分子名称: | CHLORIDE ION, Distal tail protein, TERBIUM(III) ION, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Lassalle, L, Arnaud, C.-A, Breyton, C, Madern, D, Coquelle, N, Maury, O, Girard, E. | 登録日 | 2016-11-17 | 公開日 | 2017-09-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence. Chem Sci, 8, 2017
|
|
6EU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eu3 by Molmil](/molmil-images/mine/6eu3) | Apo RNA Polymerase III - closed conformation (cPOL3) | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Abascal-Palacios, G, Ramsay, E.P, Beuron, F, Morris, E, Vannini, A. | 登録日 | 2017-10-27 | 公開日 | 2018-01-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis of RNA polymerase III transcription initiation. Nature, 553, 2018
|
|
6F2M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f2m by Molmil](/molmil-images/mine/6f2m) | Structure of the bacteriophage T5 distal tail protein pb9 co-crystallized with 10mM Tb-Xo4 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Distal tail protein, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Breyton, C, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
|
|
3NP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3np5 by Molmil](/molmil-images/mine/3np5) | |
8A41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a41 by Molmil](/molmil-images/mine/8a41) | Nudaurelia capensis omega virus procapsid at pH7.6 (insect cell expressed VLPs) | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-06-10 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.88 Å) | 主引用文献 | Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs) To be published
|
|
6PS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ps1 by Molmil](/molmil-images/mine/6ps1) | XFEL beta2 AR structure by ligand exchange from Alprenolol to Timolol. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, CHOLESTEROL, ... | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
|
|
4Y8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y8o by Molmil](/molmil-images/mine/4y8o) | |
6EXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6exy by Molmil](/molmil-images/mine/6exy) | Neutron crystal structure of perdeuterated galectin-3C in complex with glycerol | 分子名称: | GLYCEROL, Galectin-3 | 著者 | Manzoni, F, Schrader, T.E, Ostermann, A, Oksanen, E, Logan, D.T. | 登録日 | 2017-11-10 | 公開日 | 2018-09-12 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.1 Å), X-RAY DIFFRACTION | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61, 2018
|
|
8A3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a3c by Molmil](/molmil-images/mine/8a3c) | Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs) | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-06-08 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs) To be published
|
|
8A6J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8a6j by Molmil](/molmil-images/mine/8a6j) | Nudaurelia capensis omega virus maturation intermediate captured at pH6.25 (insect cell expressed VLPs) | 分子名称: | p70 | 著者 | Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P. | 登録日 | 2022-06-17 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Decoding virus maturation with cryo-EM structures of intermediates To be published
|
|
6F9Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6f9q by Molmil](/molmil-images/mine/6f9q) | Binary complex of a 7S-cis-cis-nepetalactol cyclase from Nepeta mussinii with NAD+ | 分子名称: | 7S-cis-cis-nepetalactol cyclase, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Lichman, B.R, Kamileen, M.O, Titchiner, G, Saalbach, G, Stevenson, C.E.M, Lawson, D.M, O'Connor, S.E. | 登録日 | 2017-12-15 | 公開日 | 2018-12-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis. Nat. Chem. Biol., 15, 2019
|
|
7ZLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zlg by Molmil](/molmil-images/mine/7zlg) | Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with acceptor peptide and bound to CMT2-Fab and anti-Fab nanobody | 分子名称: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | 著者 | Bloch, J.S, Mukherjee, S, Mao, R, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | 登録日 | 2022-04-15 | 公開日 | 2023-01-11 | 最終更新日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat.Chem.Biol., 19, 2023
|
|
6P82
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p82 by Molmil](/molmil-images/mine/6p82) | |
5MTK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mtk by Molmil](/molmil-images/mine/5mtk) | Crystal structure of human Caspase-1 with (3S,6S,10aS)-N-((2S,3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-6-(isoquinoline-1-carboxamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide (PGE-3935199) | 分子名称: | (3~{S})-3-[[(3~{S},6~{S},10~{a}~{S})-6-(isoquinolin-1-ylcarbonylamino)-5-oxidanylidene-2,3,6,7,8,9,10,10~{a}-octahydro-1~{H}-pyrrolo[1,2-a]azocin-3-yl]carbonylamino]-4-oxidanyl-butanoic acid, Caspase-1 | 著者 | Brethon, A, Chantalat, L, Christin, O, Clary, L, Fournier, J.F, Gastreich, M, Harris, C, Pascau, J, Isabet, T, Rodeschin, V, Thoreau, E, Roche, D. | 登録日 | 2017-01-09 | 公開日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Playing against the odds: scaffold hopping from 3D-fragments To Be Published
|
|
6S8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s8r by Molmil](/molmil-images/mine/6s8r) | |
7ZLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zlh by Molmil](/molmil-images/mine/7zlh) | Cryo-EM structure of C-mannosyltransferase CeDPY19, in apo state, bound to CMT2-Fab and anti-Fab nanobody | 分子名称: | Anti-Fab nanobody, C-mannosyltransferase dpy-19, CMT2-Fab heavy chain, ... | 著者 | Bloch, J.S, Mukherjee, S, Irobalieva, R, Kossiakoff, A.A, Goddard-Borger, E.D, Locher, K.P. | 登録日 | 2022-04-15 | 公開日 | 2023-01-11 | 最終更新日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nat.Chem.Biol., 19, 2023
|
|