PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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1L8S	CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + LPC-ether + ACETATE + PHOSPHATE IONS) 分子名称: 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ACETATE ION, CALCIUM ION, ... 著者 Pan, Y.H, Bahnson, B.J. 登録日 2002-03-21 公開日 2002-12-25 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of phospholipase A2 Complex with the Hydrolysis Products of Platelet Activating Factor: Equilibrium Binding of Fatty Acid and Lysophospholipid-ether at the Active Site may be Mutually Exclusive Biochemistry, 41, 2002
2DZO	Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3 分子名称: 26S protease regulatory subunit 6B homolog, Probable 26S proteasome regulatory subunit p28 著者 Nakamura, Y, Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-09-29 公開日 2007-10-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3 To be Published
1LA3	Solution structure of recoverin mutant, E85Q 分子名称: CALCIUM ION, MYRISTIC ACID, Recoverin 著者 Ames, J.B, Hamasaki, N, Molchanova, T. 登録日 2002-03-27 公開日 2002-06-19 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 Structure and calcium-binding studies of a recoverin mutant (E85Q) in an allosteric intermediate state. Biochemistry, 41, 2002
3ION	PDK1 in complex with Compound 8h 分子名称: 2-(5-{[(2S)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine, 3-phosphoinositide-dependent protein kinase 1, SULFATE ION 著者 Olland, A.M. 登録日 2009-08-14 公開日 2010-02-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur.J.Med.Chem., 45, 2010
2E0L	Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) 分子名称: CADMIUM ION, CHLORIDE ION, Ribonuclease 著者 Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. 登録日 2006-10-10 公開日 2007-08-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines Protein Sci., 16, 2007
1IP2	G48A HUMAN LYSOZYME 分子名称: LYSOZYME C, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2001-04-20 公開日 2001-11-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
3FI4	P38 kinase crystal structure in complex with RO4499 分子名称: (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Knapp, M, Dunten, P. 登録日 2008-12-10 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
1XXS	Structural insights for fatty acid binding in a Lys49 phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid 分子名称: Phospholipase A2 homolog 2, STEARIC ACID, SULFATE ION 著者 Watanabe, L, Soares, A.M, Ward, R.J, Fontes, M.R, Arni, R.K. 登録日 2004-11-08 公開日 2005-03-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights for fatty acid binding in a Lys49-phospholipase A(2): crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid Biochimie, 87, 2005
1IZH	Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants 分子名称: proteinase, {(1S)-1-BENZYL-4-[3-CARBAMOYL-1-(1-CARBAMOYL-2-PHENYL-ETHYLCARBAMOYL)-(S)-PROPYLCARBAMOYL]-2-OXO-5-PHENYL-PENTYL}-CARBAMIC ACID TERT-BUTYL ESTER 著者 Weber, J, Mesters, J.R, Lepsik, M, Prejdova, J, Svec, M, Sponarova, J, Mlcochova, P, Skalicka, K, Strisovsky, K, Uhlikova, T, Soucek, M, Machala, L, Stankova, M, Vondrasek, J, Klimkait, T, Kraeusslich, H.-G, Hilgenfeld, R, Konvalinka, J. 登録日 2002-10-02 公開日 2002-12-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unusual Binding Mode of an HIV-1 Protease Inhibitor Explains its Potency against Multi-drug-resistant Virus Strains J.MOL.BIOL., 324, 2002
1XUJ	TRYPSIN-KETO-BABIM-ZN+2, PH 8.2 分子名称: BIS(5-AMIDINO-BENZIMIDAZOLYL)METHANONE ZINC, CALCIUM ION, SULFATE ION, ... 著者 Katz, B.A, Clark, J.M, Finer-Moore, J.S, Jenkins, T.E, Johnson, C.R, Rose, M.J, Luong, C, Moore, W.R, Stroud, R.M. 登録日 1997-10-10 公開日 1998-11-11 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Design of potent selective zinc-mediated serine protease inhibitors. Nature, 391, 1998
2EB8	Crystal Structure of Cu(II)(Sal-Phe)/apo-Myoglobin 分子名称: (N-SALICYLIDEN-L-PHENYLALANATO)-COPPER(II), Myoglobin, PHOSPHATE ION 著者 Abe, S, Okazaki, S, Ueno, T, Hikage, T, Suzuki, A, Yamane, T, Watanabe, Y. 登録日 2007-02-07 公開日 2007-07-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Design and Structure Analysis of Artificial Metalloproteins: Selective Coordination of His64 to Copper Complexes with Square-Planar Structure in the apo-Myoglobin Scaffold Inorg.Chem., 46, 2007
2RG5	Phenylalanine pyrrolotriazine p38 alpha map kinase inhibitor compound 11B 分子名称: Mitogen-activated protein kinase 14, N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 著者 Sack, J.S. 登録日 2007-10-02 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha Mitogen-Activated Protein Kinase Inhibitors J.Med.Chem., 51, 2008
2E9O	Structure of h-CHK1 complexed with AA582939 分子名称: 4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID, Serine/threonine-protein kinase Chk1 著者 Park, C. 登録日 2007-01-26 公開日 2008-01-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors. Bioorg.Med.Chem., 15, 2007
1IX0	I59A-3SS human lysozyme 分子名称: SODIUM ION, lysozyme 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 2002-06-06 公開日 2003-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Buried water molecules contribute to the conformational stability of a protein PROTEIN ENG., 16, 2003
1XWC	Drosophila thioredoxin, reduced, P6522 分子名称: thioredoxin 著者 Wahl, M.C, Irmler, A, Hecker, B, Schirmer, R.H, Becker, K. 登録日 2004-10-29 公開日 2004-11-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster J.Mol.Biol., 345, 2005
3FMN	P38 kinase crystal structure in complex with RO2530 分子名称: 6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 P38 kinase crystal structure in complex with RO2530 To be Published
1TLD	CRYSTAL STRUCTURE OF BOVINE BETA-TRYPSIN AT 1.5 ANGSTROMS RESOLUTION IN A CRYSTAL FORM WITH LOW MOLECULAR PACKING DENSITY. ACTIVE SITE GEOMETRY, ION PAIRS AND SOLVENT STRUCTURE 分子名称: BETA-TRYPSIN, CALCIUM ION, SULFATE ION 著者 Bartunik, H.D, Summers, L.J, Bartsch, H.H. 登録日 1989-07-24 公開日 1990-01-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of bovine beta-trypsin at 1.5 A resolution in a crystal form with low molecular packing density. Active site geometry, ion pairs and solvent structure. J.Mol.Biol., 210, 1989
2EC3	Solution structure of the 11th FN1 domain from human Fibronectin 1 分子名称: Fibronectin 著者 Sano, R, Hayashi, F, Izumi, K, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-09 公開日 2008-03-04 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of the 11th FN1 domain from human Fibronectin 1 To be Published
2ZAZ	Crystal structure of P38 in complex with 4-anilino quinoline inhibitor 分子名称: 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde, ACETATE ION, GLYCEROL, ... 著者 Somers, D.O. 登録日 2007-10-12 公開日 2008-01-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode Bioorg.Med.Chem.Lett., 18, 2008
2EDB	Solution structure of the fourth fibronectin type III domain of human Netrin receptor DCC 分子名称: Netrin receptor DCC 著者 Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-14 公開日 2008-03-04 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the fourth fibronectin type III domain of human Netrin receptor DCC To be Published
1J4W	COMPLEX OF THE KH3 and KH4 DOMAINS OF FBP WITH A SINGLE_STRANDED 29mer DNA OLIGONUCLEOTIDE FROM THE FUSE ELEMENT OF THE C-MYC ONCOGENE 分子名称: DNA (5'-D(*GP*TP*A*TP*AP*TP*TP*CP*CP*CP*TP*CP*GP*GP*G*AP*TP*TP*TP*TP*TP*TP*AP*TP*TP*TP*TP*GP*T)-3'), FUSE binding protein 著者 Clore, G.M, Braddock, D.T. 登録日 2001-11-30 公開日 2002-03-06 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of KH domains from FBP bound to single-stranded DNA. Nature, 415, 2002
1IZR	F46A mutant of bovine pancreatic ribonuclease A 分子名称: RIBONUCLEASE A 著者 Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. 登録日 2002-10-11 公開日 2003-11-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
1V2V	Benzamidine in complex with bovine trypsin variant X(SSAI)bT.C1 分子名称: BENZAMIDINE, CALCIUM ION, SULFATE ION, ... 著者 Rauh, D, Klebe, G, Stubbs, M.T. 登録日 2003-10-17 公開日 2004-06-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Understanding protein-ligand interactions: the price of protein flexibility J.Mol.Biol., 335, 2004
1J52	Recombinant sperm whale myoglobin in the presence of 7atm xenon 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, XENON, ... 著者 Liong, E.C, Phillips Jr, G.N. 登録日 2002-01-08 公開日 2003-11-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Internal Cavities in Myoglobin: Implications for Protein Action To be Published
2EF2	Crystal Structure of an Artificial Metalloprotein:Rh(Phebox-Ph)/apo-A71G Myoglobin 分子名称: Myoglobin, PHOSPHATE ION, [2,6-BIS(4-PHENYL)-1,3-OXAZOLIN-2-YL]RHODIUM(III) 著者 Abe, S, Satake, Y, Okazaki, S, Ueno, T, Hikage, T, Suzuki, A, Yamane, T, Nakajima, H, Watanabe, Y. 登録日 2007-02-20 公開日 2007-10-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Incorporation of a Phebox Rhodium Complex into apo-Myoglobin Affords a Stable Organometallic Protein Showing Unprecedented Arrangement of the Complex in the Cavity ORGANOMETALLICS, 26, 2007

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