PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3G61	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding 分子名称: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a 著者 Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G. 登録日 2009-02-05 公開日 2009-03-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (4.35 Å) 主引用文献 Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science, 323, 2009
3G33	Crystal structure of CDK4/cyclin D3 分子名称: CCND3 protein, Cell division protein kinase 4 著者 Takaki, T, Echalier, A, Brown, N.R, Hunt, T, Endicott, J.A, Noble, M.E.M. 登録日 2009-02-01 公開日 2009-03-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of CDK4/cyclin D3 has implications for models of CDK activation. Proc.Natl.Acad.Sci.USA, 106, 2009
3G3H	Crystal structure of the GluR6 ligand binding domain dimer K665R I749L Q753K mutant with glutamate and NaCl at 1.5 Angstrom resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... 著者 Chaudhry, C, Mayer, M.L. 登録日 2009-02-02 公開日 2009-06-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3G4M	Crystal structure of guanine riboswitch bound to 2-aminopurine 分子名称: 9H-purin-2-amine, ACETATE ION, COBALT HEXAMMINE(III), ... 著者 Gilbert, S.D, Batey, R.T. 登録日 2009-02-04 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Adaptive ligand binding by the purine riboswitch in the recognition of Guanine and adenine analogs. Structure, 17, 2009
3G3K	Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K E757Q mutant with glutamate and NaCl at 1.24 Angstrom resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... 著者 Chaudhry, C, Mayer, M.L. 登録日 2009-02-02 公開日 2009-06-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3G51	Structural diversity of the active conformation of the N-terminal kinase domain of p90 ribosomal S6 kinase 2 分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-3 著者 Kurinov, I. 登録日 2009-02-04 公開日 2009-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2 Plos One, 4, 2009
3FXZ	Crystal structure of PAK1 kinase domain with ruthenium complex lambda-FL172 分子名称: OCTAHEDRAL RU-PYRIDOCARBAZOLE, Serine/threonine-protein kinase PAK 1 著者 Maksimoska, J, Marmorstein, R, Meggers, E. 登録日 2009-01-21 公開日 2009-02-17 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130, 2008
3G3J	Crystal structure of the GluR6 ligand binding domain dimer I442H K494E K665R I749L Q753K mutant with glutamate and NaCl at 1.32 Angstrom resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... 著者 Chaudhry, C, Mayer, M.L. 登録日 2009-02-02 公開日 2009-06-02 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.321 Å) 主引用文献 Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3HLO	Crystal structure of chemically synthesized 'covalent dimer' [Gly51/D-Ala51']HIV-1 protease 分子名称: 'covalent dimer' [Gly51/D-Ala51'] HIV-1 protease, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide 著者 Torbeev, V.Y, Kent, S.B.H. 登録日 2009-05-27 公開日 2011-07-27 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011
3FIE	Crystal structure of Clostridium botulinum neurotoxin serotype F catalytic domain with an inhibitor (inh1) 分子名称: BOTULINUM NEUROTOXIN TYPE F, ZINC ION, fragment of Vesicle-associated membrane protein 2 著者 Agarwal, R, Swaminathan, S. 登録日 2008-12-11 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F. Nat.Struct.Mol.Biol., 16, 2009
3G3F	Crystal structure of the GluR6 ligand binding domain dimer with glutamate and NaCl at 1.38 Angstrom resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor, ... 著者 Chaudhry, C, Mayer, M.L. 登録日 2009-02-02 公開日 2009-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.377 Å) 主引用文献 Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization. Embo J., 28, 2009
3FY0	Crystal structure of PAK1 kinase domain with ruthenium complex DW1 分子名称: Ruthenium pyridocarbazole, Serine/threonine-protein kinase PAK 1 著者 Maksimoska, J, Marmorstein, R, Meggers, E. 登録日 2009-01-21 公開日 2009-03-03 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc., 130, 2008
3I6M	3D Structure of Torpedo californica acetylcholinesterase complexed with N-piperidinopropyl-galanthamine 分子名称: (4aS,6R,8aS)-3-methoxy-11-(3-piperidin-1-ylpropyl)-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lamba, D, Bartolucci, C. 登録日 2009-07-07 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Probing Torpedo californica acetylcholinesterase catalytic gorge with two novel bis-functional galanthamine derivatives. J.Med.Chem., 53, 2010
3GX3	Crystal structure of the T. tengcongensis SAM-I riboswitch variant U34C/A94G bound with SAH 分子名称: MAGNESIUM ION, POTASSIUM ION, RNA (94-MER), ... 著者 Montange, R.K, Batey, R.T. 登録日 2009-04-01 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch. J.Mol.Biol., 396, 2010
3H5V	Crystal structure of the GluR2-ATD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 著者 Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. 登録日 2009-04-22 公開日 2009-06-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
3H6H	Crystal structure of the GluR6 amino terminal domain dimer assembly MPD form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glutamate receptor, ... 著者 Kumar, J, Mayer, M.L. 登録日 2009-04-23 公開日 2009-05-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 The N-terminal domain of GluR6-subtype glutamate receptor ion channels. Nat.Struct.Mol.Biol., 16, 2009
3HKL	Crystal Structure of the Frizzled-like Cysteine-rich Domain of MuSK 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Muscle, skeletal receptor tyrosine protein kinase 著者 Stiegler, A.L, Hubbard, S.R. 登録日 2009-05-24 公開日 2009-08-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK. J.Mol.Biol., 393, 2009
3HKB	Tubulin: RB3 Stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. 登録日 2009-05-23 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HDH	PIG HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE REVISITED: SEQUENCE ANALYSIS AND CRYSTAL STRUCTURE DETERMINATION 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE) 著者 Barycki, J.J, O'Brien, L.K, Birktoft, J.J, Strauss, A.W, Banaszak, L.J. 登録日 1999-04-13 公開日 1999-10-08 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Pig heart short chain L-3-hydroxyacyl-CoA dehydrogenase revisited: sequence analysis and crystal structure determination. Protein Sci., 8, 1999
3HKC	Tubulin-ABT751: RB3 stathmin-like domain complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. 登録日 2009-05-23 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HKE	Tubulin-T138067: RB3 stathmin-like domain complex 分子名称: 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. 登録日 2009-05-23 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3HKD	Tubulin-TN16 : RB3 stathmin-like domain complex 分子名称: (3Z,5S)-5-benzyl-3-[1-(phenylamino)ethylidene]pyrrolidine-2,4-dione, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M. 登録日 2009-05-23 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Variations in the colchicine-binding domain provide insight into the structural switch of tubulin Proc.Natl.Acad.Sci.USA, 106, 2009
3IAW	Crystal structure of a chemically synthesized 203 amino acid 'covalent dimer' [Gly51;Aib51']HIV-1 protease molecule complexed with MVT-101 reduced isostere inhibitor at 1.6 A resolution 分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, [Gly51;Aib51'] 'covalent dimer' HIV-1 protease 著者 Torbeev, V.Y, Kent, S.B.H. 登録日 2009-07-14 公開日 2011-04-27 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc.Natl.Acad.Sci.USA, 108, 2011
3IJ7	Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase 分子名称: 4-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranosyl fluoride, 4-O-methyl-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-5-fluoro-alpha-L-idopyranose, CALCIUM ION, ... 著者 Li, C, Zhang, R, Withers, S.G, Brayer, G.D. 登録日 2009-08-03 公開日 2009-10-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase Biochemistry, 48, 2009
3FII	Crystal structure of Clostridium botulinum neurotoxin serotype F catalytic domain with an inhibitor (inh2) 分子名称: BOTULINUM NEUROTOXIN TYPE F, ZINC ION, fragment of Vesicle-associated membrane protein 2 著者 Agarwal, R, Swaminathan, S. 登録日 2008-12-11 公開日 2009-06-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Mode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin F. Nat.Struct.Mol.Biol., 16, 2009

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