PDB: 19952 件ウェブページステータス検索Chemie searchBIRD

---

8SHZ	Structure of human cGAS 分子名称: Cyclic GMP-AMP synthase, ZINC ION 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
3L9Q	Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain 分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION 著者 Vaithiyalingam, S, Eichman, B.F, Chazin, W.J. 登録日 2010-01-05 公開日 2010-07-14 最終更新日 2011-11-16 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase. Proc.Natl.Acad.Sci.USA, 107, 2010
8SJ1	Structure of ternary complex of cGAS with dsDNA and bound 3'-dATP 分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SJ0	Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SKT	Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-20 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SI0	Structure of binary complex of human cGAS and bound cGAMP 分子名称: Cyclic GMP-AMP synthase, ZINC ION, cGAMP 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SHY	Structure of binary complex of mouse cGAS QN and bound ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ZINC ION 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SJ2	Structure of ternary complex of cGAS with dsDNA and bound ATP and 2'-dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8SJ8	Structure of binary complex of human cGAS and bound ppp(2'-5')GpG 分子名称: Cyclic GMP-AMP synthase, ZINC ION, [[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
3LCS	Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain 分子名称: ALK tyrosine kinase receptor, GLYCEROL, STAUROSPORINE 著者 Lee, C.C. 登録日 2010-01-11 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain. Biochem.J., 430, 2010
8T0N	Structure of Compound 4 bound to human ALDH1A1 分子名称: 2-methoxy-6-{[(1-propyl-1H-benzimidazol-2-yl)amino]methyl}phenol, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ... 著者 Hurley, T.D. 登録日 2023-06-01 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes. Chem.Biol.Interact., 391, 2024
8T0T	Structure of Compound 4 bound to human ALDH1A1 分子名称: 1-(4-{6-fluoro-3-[4-(methanesulfonyl)piperazine-1-carbonyl]quinolin-4-yl}phenyl)cyclopropane-1-carbonitrile, Aldehyde dehydrogenase 1A1, CHLORIDE ION, ... 著者 Hurley, T.D. 登録日 2023-06-01 公開日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes. Chem.Biol.Interact., 391, 2024
3BK9	H55A mutant of tryptophan 2,3-dioxygenase from Xanthomonas campestris 分子名称: PROTOPORPHYRIN IX CONTAINING FE, TRYPTOPHAN, Tryptophan 2,3-dioxygenase 著者 Bruckmann, C, Mowat, C.G. 登録日 2007-12-06 公開日 2008-09-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding Biochemistry, 47, 2008
3LSF	Piracetam bound to the ligand binding domain of GluA2 分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ahmed, A.H, Ptak, C.P, Oswald, R.E. 登録日 2010-02-12 公開日 2010-03-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
3C45	Human dipeptidyl peptidase IV/CD26 in complex with a fluoroolefin inhibitor 分子名称: (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Edmondson, S.D, Weber, A.E. 登録日 2008-01-29 公開日 2008-04-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18, 2008
3CVF	Crystal Structure of the carboxy terminus of Homer3 分子名称: Homer protein homolog 3 著者 Hayashi, M.K, Stearns, M.H, Giannini, V, Xu, R.-M, Sala, C, Hayashi, Y. 登録日 2008-04-18 公開日 2009-03-31 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The postsynaptic density proteins Homer and Shank form a polymeric network structure. Cell(Cambridge,Mass.), 137, 2009
3LSL	Piracetam bound to the ligand binding domain of GluA2 (flop form) 分子名称: 2-(2-oxopyrrolidin-1-yl)acetamide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ahmed, A.H, Oswald, R.E. 登録日 2010-02-12 公開日 2010-03-16 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.122 Å) 主引用文献 Piracetam Defines a New Binding Site for Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors. J.Med.Chem., 53, 2010
7WW4	Crystal structure of multidomain beta-1,3(4)-glucanase 分子名称: CALCIUM ION, GLYCEROL, beta-1,3(4)-glucanase 著者 Jiang, Z.Q, Ma, J.W. 登録日 2022-02-12 公開日 2023-02-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.23006082 Å) 主引用文献 Crystal structure of multidomain beta-1,3(4)-glucanase To be published
7WWC	Crystal structure of beta-1,3(4)-glucanase with Laminaritriose 分子名称: beta-1,3(4)-glucanase, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose 著者 Jiang, Z.Q, Ma, J.W. 登録日 2022-02-12 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2021625 Å) 主引用文献 Crystal structure of beta-1,3(4)-glucanase with Laminaritriose To Be Published
8TEK	Baseplate of Nexin-dynein regulatory complex from Tetrahymena thermophila 分子名称: CFAP20, Cilia- and flagella-associated protein 91, Coiled-coil protein, ... 著者 Ghanaeian, A.G, Black, C.S, Yang, S.K, Bui, K.H. 登録日 2023-07-06 公開日 2023-09-20 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
3CQF	Crystal structure of anthrolysin O (ALO) 分子名称: Thiol-activated cytolysin 著者 Bourdeau, R.W, Malito, E, Tang, W.J. 登録日 2008-04-02 公開日 2009-03-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Cellular Functions and X-ray Structure of Anthrolysin O, a Cholesterol-dependent Cytolysin Secreted by Bacillus anthracis J.Biol.Chem., 284, 2009
8TH8	Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila 分子名称: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ... 著者 Ghanaeian, A.G, Bui, K.H. 登録日 2023-07-14 公開日 2023-09-20 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
8TID	Combined linker domain of N-DRC and associated proteins Tetrahymena 分子名称: AAA family ATPase CDC48 subfamily protein, CFAP20, Calmodulin 7-2, ... 著者 Ghanaeian, A.G, Majhi, S.M, McCaffrey, C.M, Nami, B.N, Black, C.B, Yang, S.K, Legal, T.L, Papoulas, O.P, Janowska, M.J, Valente-Paterno, M.V, Marcotte, E.M, Wloga, D.W, Bui, K.H. 登録日 2023-07-19 公開日 2023-09-27 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism. Nat Commun, 14, 2023
7XLZ	Structure of siderophore-interacting protein from Vibrio anguillarum 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Siderophore-interacting protein 著者 Ma, Q, Liu, C, Han, Y. 登録日 2022-04-23 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Structure of siderophore-interacting protein from Vibrio anguillarum To Be Published
3MDB	Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, Kinesin-like protein KIF13B, ... 著者 Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-03-30 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.952 Å) 主引用文献 Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 to be published

<506507508509510511512513514515516517518519520521>