PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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8HNF	Crystal structure of the ancestral GH19 chitinase Anc5 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Anc5, ... 著者 Kozome, D, Laurino, P. 登録日 2022-12-07 公開日 2023-12-13 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site. Nat Commun, 15, 2024
8HMX	WDR5 in complex with histone H3Q5his peptide 分子名称: WD repeat-containing protein 5, histone H3Q5his peptide 著者 Li, H.T, Zhao, S, Wang, H.F. 登録日 2022-12-06 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 WDR5 in complex with histone H3Q5his peptide To Be Published
4WVV	Chicken Galectin-8 N-terminal domain complexed with lactose 分子名称: Galectin, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose 著者 Ruiz, F.M, Romero, A. 登録日 2014-11-07 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.205 Å) 主引用文献 Combining Crystallography and Hydrogen-Deuterium Exchange to Study Galectin-Ligand Complexes. Chemistry, 21, 2015
4WW3	Crystal structure of the lumi intermediate of squid rhodopsin 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DOCOSANE, PALMITIC ACID, ... 著者 Murakami, M, Kouyama, T. 登録日 2014-11-10 公開日 2015-06-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic Study of the LUMI Intermediate of Squid Rhodopsin Plos One, 10, 2015
8HNE	Crystal structure of the ancestral GH19 chitinase Anc4 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Anc4, ... 著者 Kozome, D, Laurino, P. 登録日 2022-12-07 公開日 2023-12-13 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Remote loop evolution reveals a complex biological function for chitinase enzymes beyond the active site. Nat Commun, 15, 2024
4WWC	Crystal structure of full length YvoA in complex with palindromic operator DNA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(P*CP*AP*GP*TP*GP*GP*TP*CP*TP*AP*GP*AP*CP*CP*AP*CP*TP*GP*G)-3'), HTH-type transcriptional repressor YvoA 著者 Grau, F.C, Fillenberg, S.B, Muller, Y.A. 登録日 2014-11-10 公開日 2015-01-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.903 Å) 主引用文献 Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR. Nucleic Acids Res., 43, 2015
8HQZ	Baseplate of DT57C bacteriophage in the full state 分子名称: Baseplate hub protein, Distal tail protein, L-shaped tail fiber assembly, ... 著者 Ayala, R, Moiseenko, A.V, Chen, T.H, Kulikov, E.E, Golomidova, A.K, Orekhov, P.S, Street, M.A, Sokolova, O.S, Letarov, A.V, Wolf, M. 登録日 2022-12-14 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Nearly complete structure of bacteriophage DT57C reveals architecture of head-to-tail interface and lateral tail fibers. Nat Commun, 14, 2023
8HD8	Crystal structure of TMPRSS2 in complex with 212-148 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... 著者 Wang, H, Liu, X, Sun, L, Yang, H. 登録日 2022-11-03 公開日 2023-12-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
4WWP	Crystal structure of human PI3K-gamma in complex with pyridinylquinoline inhibitor N-{(1S)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine 分子名称: GLYCEROL, N-{(1S)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, ... 著者 Whittington, D.A, Tang, J, Yakowec, P. 登録日 2014-11-11 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K delta Inhibitors for Inflammation and Autoimmune Disease. J.Med.Chem., 58, 2015
4WX5	pore-forming thermostable direct hemolysin from Grimontia hollisae 分子名称: Hemolysin, heat labile 著者 Wang, Y.-K, Wu, T.-K, Li, T.-H.T. 登録日 2014-11-13 公開日 2015-11-18 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Multiple pleomorphic tetramers of pore-forming thermostable direct hemolysin from Grimontia hollisae in exerting membrane binding and hemolytic activity To be published
8HOR	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Phe(4CH3)-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Phe(4CH3)-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
4WXB	Crystal Structure of Serine Hydroxymethyltransferase from Streptococcus thermophilus 分子名称: CACODYLATE ION, CITRIC ACID, GLYCEROL, ... 著者 Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. 登録日 2014-11-13 公開日 2015-02-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids. Angew.Chem.Int.Ed.Engl., 54, 2015
8HOS	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with Im-C6-Phe(4NO2)-Tyr 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-C6-Phe(4NO2)-Tyr, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
8HOZ	Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Nirmatrelvir 分子名称: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 著者 Lin, M, Liu, X. 登録日 2022-12-11 公開日 2023-12-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Nirmatrelvir To Be Published
4WH4	Protein GB1 Quadruple Mutant I6H/N8H/K28H/Q32H 分子名称: GLYCEROL, Immunoglobulin G-binding protein G, SULFATE ION 著者 Cunningham, T.C, Horne, W.S, Saxena, S. 登録日 2014-09-19 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The double-histidine Cu2+-binding motif: a highly rigid, site-specific spin probe for electron spin resonance distance measurements. Angew.Chem.Int.Ed.Engl., 54, 2015
8HO8	The cryo-EM structure of cellobiose phosphorylase from Clostridium thermocellum in complex with cellobiose 分子名称: Cellobiose phosphorylase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose 著者 Iriya, S, Kuga, T, Sunagawa, N, Igarashi, K. 登録日 2022-12-09 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.24 Å) 主引用文献 The cryo-EM structure of cellobiose phosphorylase from Clostridium thermocellum in complex with cellobiose To Be Published
4WH5	Crystal structure of lincosamide antibiotic adenylyltransferase LnuA, lincomycin-bound 分子名称: CHLORIDE ION, LINCOMYCIN, Lincosamide resistance protein, ... 著者 Stogios, P.J, Dong, A, Minasov, G, Evdokimova, E, Egorova, O, Kudritska, M, Yim, O, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-09-20 公開日 2014-11-05 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 CRYSTAL STRUCTURE OF LINCOSAMIDE ANTIBIOTIC ADENYLYLTRANSFERASE LNUA, LINCOMYCIN BOUND To Be Published
4WHF	Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one 分子名称: 1-(3,4,5-trihydroxyphenyl)decan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Wang, Y, Hou, P.P, Wu, Q, Lin, T.W. 登録日 2014-09-22 公開日 2015-09-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
8HO3	Capsid of DT57C bacteriophage in the full state 分子名称: Major head protein 著者 Ayala, R, Moiseenko, A.V, Chen, T.H, Kulikov, E.E, Golomidova, A.K, Orekhov, P.S, Street, M.A, Sokolova, O.S, Letarov, A.V, Wolf, M. 登録日 2022-12-09 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Nearly complete structure of bacteriophage DT57C reveals architecture of head-to-tail interface and lateral tail fibers. Nat Commun, 14, 2023
8HEN	Crystal structure of CTSB in complex with 212-148 分子名称: 2-[4-[[(2~{S})-1-oxidanylidene-3-phenyl-1-[[(3~{S})-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]amino]propan-2-yl]carbamoyl]piperazin-1-yl]ethyl 4-carbamimidamidobenzoate, Cathepsin B, DIMETHYL SULFOXIDE, ... 著者 Wang, H, Li, D, Sun, L, Yang, H. 登録日 2022-11-08 公開日 2023-12-13 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry. Nat Commun, 14, 2023
4WHM	Crystal structure of UDP-glucose: anthocyanidin 3-O-glucosyltransferase in complex with UDP 分子名称: ACETATE ION, GLYCEROL, UDP-glucose:anthocyanidin 3-O-glucosyltransferase, ... 著者 Hiromoto, T, Honjo, E, Tamada, T, Kuroki, R. 登録日 2014-09-23 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural basis for acceptor-substrate recognition of UDP-glucose: anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea Protein Sci., 24, 2015
8HOJ	Crystal structure of UGT71AP2 in complex with UDP 分子名称: UGT71AP2, URIDINE-5'-DIPHOSPHATE 著者 Wang, Z.L, He, C, Li, F, Qiao, X, Ye, M. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Functional characterization, structural basis, and protein engineering of a rare flavonoid 2'- O -glycosyltransferase from Scutellaria baicalensis . Acta Pharm Sin B, 14, 2024
4WHT	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form 分子名称: Epitope peptide, Heavy chain of the Fab fragment derived from neutralizing antibody 3/11, Light chain of the Fab fragment derived from neutralizing antibody 3/11 著者 Krey, T, Rey, F.A. 登録日 2014-09-23 公開日 2014-12-17 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies. J.Virol., 89, 2015
4WJ2	Mycobacterial protein 分子名称: Antigen MTB48 著者 Solomonson, M, Strynadka, N.C.J. 登録日 2014-09-29 公開日 2015-02-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of EspB from the ESX-1 type VII secretion system and insights into its export mechanism. Structure, 23, 2015
8HOU	Crystal structure of the P450 BM3 heme domain mutant F87A-T268V in complex with Im-N-C4-Phe-Phe 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, Im-N-C4-Phe-Phe, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-12-10 公開日 2023-12-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023

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