8HOZ

Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Nirmatrelvir

Summary for 8HOZ

• Entry DOI: 10.2210/pdb8hoz/pdb
• Descriptor: 3C-like proteinase nsp5, (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide (3 entities in total)
• Functional Keywords: sars-cov-2, omicron, main protease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34368.12

Authors

Lin, M.,Liu, X. (deposition date: 2022-12-11, release date: 2023-12-13)

• Primary citation: Lin, M.,Liu, X.; Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) in Complex with Nirmatrelvir; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.83 Å)