3EOV
 
 | | Crystal structure of cyclophilin from Leishmania donovani ligated with cyclosporin A | | 分子名称: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | | 著者 | Venugopal, V, Dasgupta, D, Datta, A.K, Banerjee, R. | | 登録日 | 2008-09-29 | | 公開日 | 2008-11-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of Cyclophilin from Leishmania Donovani Bound to Cyclosporin at 2.6 A Resolution: Correlation between Structure and Thermodynamic Data.
Acta Crystallogr.,Sect.D, 65, 2009
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1S4A
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1HDU
 | | Crystal structure of bovine pancreatic carboxypeptidase A complexed with aminocarbonylphenylalanine at 1.75 A | | 分子名称: | CARBOXYPEPTIDASE A, D-[(AMINO)CARBONYL]PHENYLALANINE, ZINC ION | | 著者 | Cho, J.H, Ha, N.-C, Chung, S.J, Kim, D.H, Choi, K.Y, Oh, B.-H. | | 登録日 | 2000-11-17 | | 公開日 | 2001-11-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Insight Into the Stereochemistry in the Inhibition of Carboxypeptidase a with N-(Hydroxyaminocarbonyl)Phenylalanine: Binding Modes of an Enantiomeric Pair of the Inhibitor to Carboxypeptidase A
Bioorg.Med.Chem., 10, 2002
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3WQF
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3WQG
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2QJM
 | | Crystal structure of the K271E mutant of Mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and D-mannonate | | 分子名称: | D-MANNONIC ACID, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme | | 著者 | Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Vick, J.E, Gerlt, J.A, Almo, S.C. | | 登録日 | 2007-07-08 | | 公開日 | 2007-10-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry, 46, 2007
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2DNS
 | | The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine | | 分子名称: | BARIUM ION, D-PHENYLALANINE, D-amino acid amidase | | 著者 | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | | 登録日 | 2006-04-26 | | 公開日 | 2006-05-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins
J.Mol.Biol., 368, 2007
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3TRV
 | | Crystal structure of quasiracemic villin headpiece subdomain containing (F5Phe17) substitution | | 分子名称: | D-Villin-1, ISOPROPYL ALCOHOL, L-Villin-1, ... | | 著者 | Mortenson, D.E, Satyshur, K.A, Gellman, S.H, Forest, K.T. | | 登録日 | 2011-09-11 | | 公開日 | 2012-01-25 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
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2I57
 | | Crystal Structure of L-Rhamnose Isomerase from Pseudomonas stutzeri in Complex with D-Allose | | 分子名称: | D-ALLOSE, L-rhamnose isomerase, ZINC ION | | 著者 | Yoshida, H, Yamada, M, Takada, G, Izumori, K, Kamitori, S. | | 登録日 | 2006-08-24 | | 公開日 | 2006-12-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | The Structures of l-Rhamnose Isomerase from Pseudomonas stutzeri in Complexes with l-Rhamnose and d-Allose Provide Insights into Broad Substrate Specificity
J.Mol.Biol., 365, 2007
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2JUE
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2KQL
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4U8Z
 | | Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06447475) | | 分子名称: | 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile, MANGANESE (II) ION, Serine/threonine-protein kinase 24 | | 著者 | Jasti, J, Song, X, Griffor, M, Kurumbail, R.G. | | 登録日 | 2014-08-05 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor.
J.Med.Chem., 58, 2015
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4U2Y
 | | Sco GlgEI-V279S in Complex with Reaction Intermediate Azasugar | | 分子名称: | (2R,3R,4R,5R)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-3-yl alpha-D-glucopyranoside, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1 | | 著者 | Ronning, D.R, Lindenberger, J.J. | | 登録日 | 2014-07-18 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.483 Å) | | 主引用文献 | Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.
Sci Rep, 5, 2015
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4UDJ
 | | Crystal structure of b-1,4-mannopyranosyl-chitobiose phosphorylase at 1.60 Angstrom in complex with beta-D-mannopyranose and inorganic phosphate | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Ladeveze, S, Cioci, G, Potocki-Veronese, G, Tranier, S, Mourey, L. | | 登録日 | 2014-12-10 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural Bases for N-Glycan Processing by Mannoside Phosphorylase.
Acta Crystallogr.,Sect.D, 71, 2015
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4U31
 | | Sco GlgEI-V279S in Complex with maltose-C-phosphonate | | 分子名称: | 1,2-ETHANEDIOL, Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, CITRIC ACID, ... | | 著者 | Ronning, D.R, Lindenberger, J.J. | | 登録日 | 2014-07-18 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | | 主引用文献 | Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.
Sci Rep, 5, 2015
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4U33
 | | Structure of Mtb GlgE bound to maltose | | 分子名称: | Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ronning, D.R, Lindenberger, J.J. | | 登録日 | 2014-07-18 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.293 Å) | | 主引用文献 | Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.
Sci Rep, 5, 2015
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4U3C
 | | Docking Site of Maltohexaose in the Mtb GlgE | | 分子名称: | Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Ronning, D.R, Lindenberger, J.J. | | 登録日 | 2014-07-19 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | | 主引用文献 | Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.
Sci Rep, 5, 2015
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4WM9
 | | Acinetobacter baumanii OXA-24 complex with Avibactam | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | | 著者 | Mangani, S, Benvenuti, M, Docquier, J.-D. | | 登録日 | 2014-10-08 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48.
Acs Chem.Biol., 10, 2015
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4WMC
 | | OXA-48 covalent complex with Avibactam inhibitor | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, CARBON DIOXIDE | | 著者 | Mangani, S, Benvenuti, M, Docquier, J.D. | | 登録日 | 2014-10-08 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48.
Acs Chem.Biol., 10, 2015
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6Q1D
 | | Holo YfeA reconstituted by zinc soaking | | 分子名称: | Periplasmic chelated iron-binding protein YfeA, ZINC ION | | 著者 | Radka, C.D, Labiuk, S.L, DeLucas, L.J, Aller, S.G. | | 登録日 | 2019-08-03 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms.
Acta Crystallogr D Struct Biol, 75, 2019
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7AM6
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2BO8
 | | DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE | | 分子名称: | CHLORIDE ION, GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER, ... | | 著者 | Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. | | 登録日 | 2005-04-08 | | 公開日 | 2005-06-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural dissection and high-throughput screening of mannosylglycerate synthase.
Nat. Struct. Mol. Biol., 12, 2005
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4KSH
 | | Dna gyrase atp binding domain of enterococcus faecalis in complex with a small molecule inhibitor (7-({4-[(3R)-3-AMINOPYRROLIDIN-1-YL]-5-CHLORO-6-ETHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-2-YL}SULFANYL)-1,5-NAPHTHYRIDIN-1(4H)-OL) | | 分子名称: | 7-({4-[(3R)-3-aminopyrrolidin-1-yl]-5-chloro-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)-1,5-naphthyridin-1(4H)-ol, DNA gyrase subunit B, GLYCEROL | | 著者 | Bensen, D.C, Akers-Rodriguez, S, Tari, L.W. | | 登録日 | 2013-05-17 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A new class of type iia topoisomerase inhibitors with broad-spectrum antibacterial activity
To be Published
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1S2J
 | | Crystal structure of the Drosophila pattern-recognition receptor PGRP-SA | | 分子名称: | PHOSPHATE ION, Peptidoglycan recognition protein SA CG11709-PA | | 著者 | Chang, C.-I, Pili-Floury, S, Chelliah, Y, Lemaitre, B, Mengin-Lecreulx, D, Deisenhofer, J. | | 登録日 | 2004-01-08 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual l,d-carboxypeptidase activity.
PLOS BIOL., 2, 2004
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7AEN
 | | Galectin-8 N-terminal carbohydrate recognition domain in complex with methyl 3-O-((7-carboxy)quinolin-2-yl)-methoxy)-beta-D-galactopyranoside | | 分子名称: | CHLORIDE ION, GLYCEROL, Isoform 2 of Galectin-8, ... | | 著者 | Hassan, M, Klavern, V.S, Hakansson, M, Anderluh, M, Tomasic, T, Jakopin, Z, Nilsson, J.U, Kovacic, R, Walse, B, Diehl, C. | | 登録日 | 2020-09-17 | | 公開日 | 2021-07-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain
Acs Med.Chem.Lett., 12, 2021
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