PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6MUO	CENP-A nucleosome bound by two copies of CENP-C(CD) and one copy CENP-N(NT) 分子名称: Centromere protein C, Centromere protein N, DNA/RNA (147-MER), ... 著者 Allu, P.K, Black, B.E. 登録日 2018-10-23 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the Human Core Centromeric Nucleosome Complex. Curr.Biol., 29, 2019
5UE1	Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with adenine from Vibrio fischeri ES114 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ... 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-12-29 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Vibrio fischeri ES114 To Be Published
6PO4	2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII. 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, ... 著者 Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-07-03 公開日 2019-07-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII. To Be Published
5LQW	yeast activated spliceosome 分子名称: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... 著者 Rauhut, R, Luehrmann, R. 登録日 2016-08-17 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Molecular architecture of the Saccharomyces cerevisiae activated spliceosome Science, 6306, 2016
6NN6	Structure of Dot1L-H2BK120ub nucleosome complex 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Anderson, C.J, Baird, M.R, Hsu, A, Barbour, E.H, Koyama, Y, Borgnia, M.J, McGinty, R.K. 登録日 2019-01-14 公開日 2019-02-13 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural Basis for Recognition of Ubiquitylated Nucleosome by Dot1L Methyltransferase. Cell Rep, 26, 2019
6OM3	Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle 分子名称: DNA (146-MER), DNA (147-MER), Histone H2A, ... 著者 De Ioannes, P.E, Wang, M, Armache, K.-J. 登録日 2019-04-18 公開日 2019-07-10 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and function of the Orc1 BAH-nucleosome complex. Nat Commun, 10, 2019
4NCG	Discovery of Doravirine, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses 分子名称: 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl}oxy)benzonitrile, Reverse transcriptase/ribonuclease H, p51 RT 著者 Yan, Y. 登録日 2013-10-24 公開日 2014-02-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses. Bioorg.Med.Chem.Lett., 24, 2014
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-15 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
6AHD	The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-17 公開日 2018-11-14 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
4M7W	Crystal structure of purine nucleoside phosphorylase from Leptotrichia buccalis C-1013-b, NYSGRC Target 029767. 分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-12 公開日 2013-08-28 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of purine nucleoside phosphorylase from Leptotrichia buccalis C-1013-b, NYSGRC Target 029767. To be Published
5YLZ	Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-10-20 公開日 2018-07-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
5Y88	Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-08-20 公開日 2018-08-01 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
5W2E	HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor MK-8876 分子名称: 2-(4-fluorophenyl)-5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide, Genome polyprotein 著者 Lesburg, C.A, Ummat, A. 登録日 2017-06-06 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Development of a New Structural Class of Broadly Acting HCV Non-Nucleoside Inhibitors Leading to the Discovery of MK-8876. ChemMedChem, 12, 2017
5ZWO	Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... 著者 Bai, R, Wan, R, Yan, C, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
5B0Y	Crystal structure of the nucleosome containing histone H3 with the crotonylated lysine 122 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Suzuki, Y, Horikoshi, N, Kurumizaka, H. 登録日 2015-11-13 公開日 2016-01-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.557 Å) 主引用文献 Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122 Biochem.Biophys.Res.Commun., 469, 2016
4MAR	Crystal structure of purine nucleoside phosphorylase from Meiothermus ruber DSM 1279 complexed with sulfate. 分子名称: MAGNESIUM ION, Purine nucleoside phosphorylase DeoD-type, SULFATE ION 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-16 公開日 2013-10-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Crystal structure of purine nucleoside phosphorylase from Meiothermus ruber DSM 1279 complexed with sulfate. To be Published
4M3N	Crystal structure of purine nucleoside phosphorylase from Meiothermus ruber DSM 1279, NYSGRC Target 029804. 分子名称: MAGNESIUM ION, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-06 公開日 2013-08-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of purine nucleoside phosphorylase from Meiothermus ruber DSM 1279, NYSGRC Target 029804. To be Published
6OE3	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-7-fluoro-2-naphthonitrile (JLJ635), a Non-nucleoside Inhibitor 分子名称: 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Bertoletti, N, Kudalkar, S.N, Anderson, K.S, Cisneros Trigo, J.A, Jorgensen, W.L. 登録日 2019-03-27 公開日 2019-05-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV. Antiviral Res., 167, 2019
4NHO	Structure of the spliceosomal DEAD-box protein Prp28 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... 著者 Moehlmann, S, Neumann, P, Ficner, R. 登録日 2013-11-05 公開日 2014-06-18 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallogr.,Sect.D, 70, 2014
1P34	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
5ZWM	Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) 分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... 著者 Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
1P3I	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
1P3P	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
1P3K	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004
1P3A	Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants 分子名称: Histone H2A, Histone H2B, Histone H3, ... 著者 Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K. 登録日 2003-04-17 公開日 2004-02-24 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions EMBO J., 23, 2004

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