PDB: 45744 件ウェブページステータス検索Chemie searchBIRD

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2YA1	Product complex of a multi-modular glycogen-degrading pneumococcal virulence factor SpuA 分子名称: PUTATIVE ALKALINE AMYLOPULLULANASE, SODIUM ION, SULFATE ION, ... 著者 Lammerts van Bueren, A, Ficko-Blean, E, Pluvinage, B, Hehemann, J.H, Higgins, M.A, Deng, L, Ogunniyi, A.D, Stroeher, U.H, Warry, N.E, Burke, R.D, Czjzek, M, Paton, J.C, Vocadlo, D.J, Boraston, A.B. 登録日 2011-02-17 公開日 2011-04-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor. Structure, 19, 2011
2YCY	TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL 分子名称: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, SODIUM ION, ... 著者 Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. 登録日 2011-03-17 公開日 2011-06-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
3F3A	Crystal Structure of LeuT bound to L-Tryptophan and Sodium 分子名称: SODIUM ION, TETRADECANE, TRYPTOPHAN, ... 著者 Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. 登録日 2008-10-30 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
3WAY	Crystal Structure of Autotaxin in Complex with 4BoA 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2013-05-09 公開日 2013-07-31 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe Acs Chem.Biol., 8, 2013
3H4Z	Crystal Structure of an MBP-Der p 7 fusion protein 分子名称: Maltose-binding periplasmic protein fused with Allergen DERP7, SODIUM ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Pedersen, L.C, Mueller, G.A, London, R.E. 登録日 2009-04-21 公開日 2010-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J.Allergy Clin.Immunol., 125, 2010
2Y8V	Structure of chitinase, ChiC, from Aspergillus fumigatus. 分子名称: CLASS III CHITINASE, PUTATIVE, SODIUM ION 著者 Rush, C.L, Schuettelkopf, A.W, Gay, L.M, van Aalten, D.M.F. 登録日 2011-02-10 公開日 2012-02-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure of Chitinase, Chic, from Aspergillus Fumigatus. To be Published
2YGO	WIF domain-EGF-like domain 1 of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... 著者 Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. 登録日 2011-04-19 公開日 2011-07-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18, 2011
2PJP	Structure of the mRNA-binding domain of elongation factor SelB from E.coli in complex with SECIS RNA 分子名称: CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ... 著者 Soler, N, Fourmy, D, Yoshizawa, S. 登録日 2007-04-16 公開日 2007-10-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insight into a molecular switch in tandem winged-helix motifs from elongation factor SelB. J.Mol.Biol., 370, 2007
2QTB	Human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl cyclohexylalanine inhibitor 分子名称: (2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G. 登録日 2007-08-01 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 4-Arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 17, 2007
2QJU	Crystal Structure of an NSS Homolog with Bound Antidepressant 分子名称: 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE, CHLORIDE ION, LEUCINE, ... 著者 Zhou, Z, Karpowich, N.K, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2007-07-09 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science, 317, 2007
2YFO	GALACTOSIDASE DOMAIN OF ALPHA-GALACTOSIDASE-SUCROSE KINASE, AGASK, in complex with galactose 分子名称: ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK, GLYCEROL, PHOSPHATE ION, ... 著者 Sulzenbacher, G, Bruel, L, Tison-Cervera, M, Pujol, A, Nicoletti, C, Perrier, J, Galinier, A, Ropartz, D, Fons, M, Pompeo, F, Giardina, T. 登録日 2011-04-07 公開日 2011-09-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Agask, a Bifunctional Enzyme from the Human Microbiome Coupling Galactosidase and Kinase Activities J.Biol.Chem., 286, 2011
2YGM	THE X-RAY CRYSTAL STRUCTURE OF TANDEM CBM51 MODULES OF SP3GH98, THE FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71, IN COMPLEX WITH THE BLOOD GROUP B ANTIGEN 分子名称: BLOOD GROUP A-AND B-CLEAVING ENDO-BETA-GALACTOSIDASE, CALCIUM ION, SODIUM ION, ... 著者 Higgins, M.A, Ficko-Blean, E, Wright, C, Meloncelli, P.J, Lowary, T.L, Boraston, A.B. 登録日 2011-04-19 公開日 2011-06-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate Antigen Hydrolyzing Enzymes. J.Mol.Biol., 411, 2011
2YA2	Catalytic Module of the Multi-modular glycogen-degrading pneumococcal virulence factor SpuA in complex with an inhibitor. 分子名称: CALCIUM ION, PUTATIVE ALKALINE AMYLOPULLULANASE, SODIUM ION, ... 著者 Lammerts van Bueren, A, Ficko-Blean, E, Pluvinage, B, Hehemann, J.H, Higgins, M.A, Deng, L, Ogunniyi, A.D, Stroeher, U.H, Warry, N.E, Burke, R.D, Czjzek, M, Paton, J.C, Vocadlo, D.J, Boraston, A.B. 登録日 2011-02-17 公開日 2011-04-20 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor. Structure, 19, 2011
2QQU	Crystal structure of a cell-wall invertase (D239A) from Arabidopsis thaliana in complex with sucrose 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-fructofuranosidase, ... 著者 Lammens, W, Le Roy, K, Van Laere, A, Rabijns, A, Van den Ende, W. 登録日 2007-07-27 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose. J.Mol.Biol., 377, 2008
2QOE	Human Dipeptidyl Peptidase IV in complex with a Triazolopiperazine-based beta amino acid Inhibitor 分子名称: (2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G. 登録日 2007-07-20 公開日 2007-11-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
2QSV	Crystal structure of protein of unknown function from Porphyromonas gingivalis W83 分子名称: SODIUM ION, SULFATE ION, Uncharacterized protein 著者 Binkowski, T.A, Duggan, E, Shui, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2007-07-31 公開日 2007-09-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Protein of unknown function from Porphyromonas gingivalis W83. TO BE PUBLISHED
4AX9	Human thrombin complexed with Napsagatran, RO0466240 分子名称: 2-[[(2S)-4-[[(3S)-1-carbamimidoylpiperidin-3-yl]methylamino]-2-(naphthalen-2-ylsulfonylamino)-4-oxidanylidene-butanoyl] -cyclopropyl-amino]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUDIN VARIANT-1, ... 著者 Banner, D.W, D'Arcy, A, Winkler, F.K, Hilpert, K, Spinelli, S, Cambillau, C. 登録日 2012-06-11 公開日 2012-06-20 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors. J.Med.Chem., 37, 1994
4BAM	Thrombin in complex with inhibitor 分子名称: (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[(2R)-2-cyclohexyl-2-[[2-(dimethylamino)-2-oxidanylidene-ethyl]amino]ethanoyl]azetidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUDIN VARIANT-1, ... 著者 Xue, Y, Musil, D. 登録日 2012-09-14 公開日 2013-01-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Identification of Structure-Kinetic and Structure-Thermodynamic Relationships for Thrombin Inhibitors. Biochemistry, 52, 2013
4AYV	Human thrombin - inhibitor complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIRUDIN-3A', SODIUM ION, ... 著者 Banner, D.W, D'Arcy, A, Winkler, F.K, Hilpert, K. 登録日 2012-06-22 公開日 2012-08-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors. J.Med.Chem., 37, 1994
4B0O	Crystal structure of soman-aged human butyrylcholinesterase in complex with benzyl pyridinium-4-methyltrichloroacetimidate 分子名称: 1-BENZYL-4-({[(1E)-2,2,2-TRICHLOROETHANIMIDOYL]OXY}METHYL)PYRIDINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wandhammer, M, de Koning, M, van Grol, M, Noort, D, Goeldner, M, Nachon, F. 登録日 2012-07-04 公開日 2012-08-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A Step Toward the Reactivation of Aged Cholinesterases -Crystal Structure of Ligands Binding to Aged Human Butyrylcholinesterase Chem.Biol.Interact, 203, 2013
2R22	Structure of the native RNA tridecamer r(GCGUUUGAAACGC) at 1.5 A (NatMn) 分子名称: MANGANESE (II) ION, RNA (5'-R(*GP*CP*GP*UP*UP*UP*GP*AP*AP*AP*CP*GP*C)-3'), SODIUM ION 著者 Timsit, Y, Bombard, S. 登録日 2007-08-24 公開日 2007-09-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The 1.3 A structure of the tridecamer r(GCGUUUGAAACGC) TO BE PUBLISHED
3UU8	The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution 分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3UZ5	Designed protein KE59 R13 3/11H 分子名称: 5,7-dichloro-1H-benzotriazole, Kemp eliminase KE59 R13 3/11H, PHOSPHATE ION, ... 著者 Khersonsky, O, Kiss, G, Roethlisberger, D, Dym, O, Albeck, S, Houk, K.N, Baker, D, Tawfik, D.S, Israel Structural Proteomics Center (ISPC) 登録日 2011-12-07 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59. Proc.Natl.Acad.Sci.USA, 109, 2012
3USP	Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside 分子名称: CHLORIDE ION, LEUCINE, SODIUM ION, ... 著者 Wang, H, Elferich, J, Gouaux, E. 登録日 2011-11-23 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
3V1W	Molecular Basis for Multiple Ligand Binding of Calsequestrin and Potential Inhibition by Caffeine and Gallocatecin 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Subramanian, A.K, Nissen, M.N, Lewis, K.M, Sanchez, E.J, Muralidharan, A.K, Kang, C. 登録日 2011-12-10 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.908 Å) 主引用文献 Molecular Basis for Multiple Ligand Binding of Calsequestrin and Potential Inhibition by Caffeine and Gallocatecin To be Published

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