4AYV
Human thrombin - inhibitor complex
Summary for 4AYV
| Entry DOI | 10.2210/pdb4ayv/pdb |
| Related | 4AYY 4AZ2 |
| Descriptor | THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN-3A', ... (7 entities in total) |
| Functional Keywords | hydrolase-inhibitor complex, hydrolase, hydrolase/inhibitor |
| Biological source | HOMO SAPIENS (HUMAN) More |
| Total number of polymer chains | 3 |
| Total formula weight | 35348.31 |
| Authors | Banner, D.W.,D'Arcy, A.,Winkler, F.K.,Hilpert, K. (deposition date: 2012-06-22, release date: 2012-08-15, Last modification date: 2020-07-29) |
| Primary citation | Hilpert, K.,Ackermann, J.,Banner, D.W.,Gast, A.,Gubernator, K.,Hadvary, P.,Labler, L.,Muller, K.,Schmid, G.,Tschopp, T.B. Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors. J.Med.Chem., 37:3889-, 1994 Cited by PubMed: 7966150DOI: 10.1021/JM00049A008 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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