PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

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8HMC	base module state 1 of Tetrahymena IFT-A 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... 著者 Ma, Y, Wu, J, Lei, M. 登録日 2022-12-03 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
4KER	Crystal structure of SsoPox W263V 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
4KEU	Crystal structure of SsoPox W263M 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
2YBG	Structure of Lys120-acetylated p53 core domain 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Arbely, E, Allen, M.D, Joerger, A.C, Fersht, A.R. 登録日 2011-03-08 公開日 2011-05-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Acetylation of Lysine 120 of P53 Endows DNA- Binding Specificity at Effective Physiological Salt Concentration. Proc.Natl.Acad.Sci.USA, 108, 2011
2YN1	Crystal Structure of Ancestral Thioredoxin Relative to Last Gamma- Proteobacteria Common Ancestor (LGPCA) from the Precambrian Period 分子名称: LGPCA THIOREDOXIN, TRIETHYLENE GLYCOL 著者 Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2012-10-11 公開日 2013-08-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
7CGV	Full consensus L-threonine 3-dehydrogenase, FcTDH-IIYM (NAD+ bound form) 分子名称: Artificial L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Motoyama, T, Hiramatsu, N, Asano, Y, Nakano, S, Ito, S. 登録日 2020-07-02 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Protein Sequence Selection Method That Enables Full Consensus Design of Artificial l-Threonine 3-Dehydrogenases with Unique Enzymatic Properties. Biochemistry, 59, 2020
7C7H	Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2l 分子名称: 2-azanylidene-N-(3-ethylphenyl)-8-oxidanyl-chromene-3-carboxamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Irie, K, Toyooka, N, Endo, S. 登録日 2020-05-25 公開日 2020-09-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer. J.Med.Chem., 63, 2020
4UZY	Crystal structure of the Chlamydomonas IFT70 and IFT52 complex 分子名称: CITRATE ANION, FLAGELLAR ASSOCIATED PROTEIN, INTRAFLAGELLAR TRANSPORT PROTEIN IFT52, ... 著者 Taschner, M, Lorentzen, E. 登録日 2014-09-09 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.477 Å) 主引用文献 Crystal Structures of Ift70/52 and Ift52/46 Provide Insight Into Intraflagellar Transport B Core Complex Assembly. J.Cell Biol., 207, 2014
4V8H	Crystal structure of HPF bound to the 70S ribosome. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Blaha, G.M, Steitz, T.A. 登録日 2011-12-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis. Science, 336, 2012
7C5Y	Crystal structure of the iota-carbonic anhydrase from eukaryotic microalga complexed with iodide 分子名称: IODIDE ION, iota-carbonic anhydrase 著者 Senda, M, Senda, T. 登録日 2020-05-20 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of a novel type of carbonic anhydrase that acts without metal cofactors. Bmc Biol., 19, 2021
7C5X	Crystal structure of the iota-carbonic anhydrase from eukaryotic microalga complexed with bicarbonate 分子名称: BICARBONATE ION, iota-carbonic anhydrase 著者 Senda, M, Senda, T. 登録日 2020-05-20 公開日 2021-04-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Characterization of a novel type of carbonic anhydrase that acts without metal cofactors. Bmc Biol., 19, 2021
6ESF	Nucleosome : Class 1 分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
7QBN	Structure of cathepsin K in complex with the azadipeptide nitrile inhibitor Gu1303 分子名称: (phenylmethyl) ~{N}-[(2~{S})-1-[[aminomethyl(methyl)amino]-methyl-amino]-1-oxidanylidene-3-phenyl-propan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... 著者 Benysek, J, Busa, M, Mares, M. 登録日 2021-11-19 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem, 37, 2022
7QBL	Structure of cathepsin K in complex with the 3-cyano-3-aza-beta-amino acid inhibitor Gu2602 分子名称: Cathepsin K, ~{tert}-butyl ~{N}-[iminomethyl-[2-[methyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]amino]carbamate 著者 Benysek, J, Busa, M, Mares, M. 登録日 2021-11-19 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem, 37, 2022
7QBM	Structure of the activation intermediate of cathepsin K in complex with the 3-cyano-3-aza-beta-amino acid inhibitor Gu2602 分子名称: ACETATE ION, Cathepsin K, MAGNESIUM ION, ... 著者 Benysek, J, Busa, M, Mares, M. 登録日 2021-11-19 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem, 37, 2022
7QBO	Structure of the activation intermediate of cathepsin K in complex with the azadipeptide nitrile inhibitor Gu1303 分子名称: (phenylmethyl) ~{N}-[(2~{S})-1-[[aminomethyl(methyl)amino]-methyl-amino]-1-oxidanylidene-3-phenyl-propan-2-yl]carbamate, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Benysek, J, Busa, M, Mares, M. 登録日 2021-11-19 公開日 2022-01-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem, 37, 2022
6ESG	Nucleosome breathing : Class 2 分子名称: DNA (141-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
6UVJ	Cocrystal of BRD4(D1) with a methyl carbamate thiazepane inhibitor 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, ... 著者 Johnson, J.A, Pomerantz, W.C.K. 登録日 2019-11-02 公開日 2020-01-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains. Acs Med.Chem.Lett., 10, 2019
6ESH	Nucleosome breathing : Class 3 分子名称: DNA (137-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
7OHS	Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae 分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.38 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
6ESI	Nucleosome breathing : Class 4 分子名称: DNA (133-MER), Histone H2A, Histone H2B 1.1, ... 著者 Bilokapic, S, Halic, M. 登録日 2017-10-20 公開日 2017-12-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
6UWX	Cocrystal of BRD4(D1) with a ethyl carbamate thiazepane inhibitor 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ethyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylate 著者 Johnson, J.A, Pomerantz, W.C.K. 登録日 2019-11-05 公開日 2020-01-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.307 Å) 主引用文献 Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains. Acs Med.Chem.Lett., 10, 2019
4KZZ	Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A 分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ... 著者 Lomakin, I.B, Steitz, T.A. 登録日 2013-05-30 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (7.0305 Å) 主引用文献 The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature, 500, 2013
6UVM	Cocrystal of BRD4(D1) with a methyl carbamate thiazepane inhibitor 分子名称: 1,2-ETHANEDIOL, 1-[(7S)-7-(thiophen-2-yl)-6,7-dihydro-1,4-thiazepin-4(5H)-yl]ethan-1-one, Bromodomain-containing protein 4 著者 Johnson, J.A, Pomerantz, W.C.K. 登録日 2019-11-03 公開日 2020-01-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains. Acs Med.Chem.Lett., 10, 2019
8RU2	Structure of the F-actin barbed end bound by formin mDia1 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024

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