PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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8J7R	Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A (J-K-St/eIF4G focused) 分子名称: Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), MAGNESIUM ION 著者 Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I. 登録日 2023-04-28 公開日 2023-08-02 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun, 14, 2023
5Y08	Solution structure of the apo doublet acyl carrier protein from prodigiosin biosynthesis 分子名称: 4-hydroxy-2,2'-bipyrrole-5-methanol synthase PigH 著者 Wattana-amorn, P. 登録日 2017-07-15 公開日 2018-12-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis. Biochemistry, 2021
1KOH	THE CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OF A NOVEL RNA-BINDING DOMAIN FOUND IN THE HUMAN TAP NUCLEAR MRNA EXPORT FACTOR 分子名称: TIP ASSOCIATING PROTEIN 著者 Ho, D.N, Coburn, G.A, Kang, Y, Cullen, B.R, Georgiadis, M.M. 登録日 2001-12-20 公開日 2002-02-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. Proc.Natl.Acad.Sci.USA, 99, 2002
5LT8	Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 分子名称: Histone-lysine N-methyltransferase SETD2, SINEFUNGIN, ZINC ION 著者 Tisi, D, Pathuri, P, Heightman, T. 登録日 2016-09-06 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem. Biol., 11, 2016
2O25	Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9 分子名称: SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-11-29 公開日 2007-01-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa To be Published
2O2O	Solution structure of domain B from human CIN85 PROTEIN 分子名称: SH3-domain kinase-binding protein 1 著者 Ababou, A, Pfuhl, M, Dikic, I, Ladbury, J.E. 登録日 2006-11-30 公開日 2007-11-13 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Investigation of Domain B from Human Cin85 Protein: Structure, Dynamics and Proline-Rich Motif Binding To be Published
2EJE	Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA 分子名称: General transcription factor II-I 著者 Doi-Katayama, Y, Hirota, H, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-16 公開日 2007-09-18 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution Structure of RSGI RUH-071, a GTF2I domain in human cDNA To be Published
4CBS	X-ray structure of quintuple mutant of human alanine glyoxylate aminotransferase, AGXT_RHEAM 分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE--PYRUVATE AMINOTRANSFERASE 著者 Yunta, C, Albert, A. 登録日 2013-10-16 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase. Biochem.J., 462, 2014
6JCQ	AAV1 in complex with AAVR 分子名称: Capsid protein, Dyslexia-associated protein KIAA0319-like protein 著者 Lou, Z, Zhang, R. 登録日 2019-01-30 公開日 2019-10-23 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Divergent engagements between adeno-associated viruses with their cellular receptor AAVR. Nat Commun, 10, 2019
1V27	Solution structure of the first C2 domain of RIM2 分子名称: Regulating synaptic membrane exocytosis protein 2 著者 Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-10-07 公開日 2004-04-07 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of the first C2 domain of RIM2 to be published
8JO2	Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA 分子名称: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... 著者 Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. 登録日 2023-06-06 公開日 2023-08-30 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA. Nucleic Acids Res., 51, 2023
7KTS	Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) 分子名称: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... 著者 Herbst, D.A, Esbin, M.N, Nogales, E. 登録日 2020-11-24 公開日 2021-11-10 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (19.09 Å) 主引用文献 Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
5MJY	Crystal structure of the His Domain Protein Tyrosine Phosphatase (HD-PTP/PTPN23) Bro1 domain (SARA complex structure) 分子名称: Tyrosine-protein phosphatase non-receptor type 23, Zinc finger FYVE domain-containing protein 9 著者 Levy, C, Gahloth, D. 登録日 2016-12-02 公開日 2017-08-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP. Structure, 25, 2017
2OCS	The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) 分子名称: 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION 著者 Papagrigoriou, E, Phillips, C, Gileadi, C, Elkins, J, Salah, E, Berridge, G, Savitsky, P, Gorrec, F, Umeano, C, Ugochukwu, E, Gileadi, O, Burgess, N, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) 登録日 2006-12-21 公開日 2007-01-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) To be Published
2E6W	Solution structure and calcium binding properties of EF-hands 3 and 4 of calsenilin 分子名称: CALCIUM ION, Calsenilin 著者 Yu, L, Sun, C, Mendoza, R, Hebert, E, Pereda-Lopez, A, Hajduk, P.J, Olejniczak, E.T. 登録日 2007-01-05 公開日 2007-11-27 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin. Protein Sci., 16, 2007
2OJ4	Crystal structure of RGS3 RGS domain 分子名称: Regulator of G-protein signaling 3 著者 Boura, E, Obsil, T. 登録日 2007-01-12 公開日 2007-01-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3). J.Struct.Biol., 170, 2010
2OGP	Solution structure of the second PDZ domain of Par-3 分子名称: Partitioning-defective 3 homolog 著者 Feng, W, Wu, H, Chen, J, Chan, L.-N, Zhang, M. 登録日 2007-01-07 公開日 2007-12-25 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 PDZ domains of par-3 as potential phosphoinositide signaling integrators Mol.Cell, 28, 2007
6GZH	Crystal Structure of Human CDK9/cyclinT1 with A86 分子名称: Cyclin-T1, Cyclin-dependent kinase 9, GLYCEROL, ... 著者 Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. 登録日 2018-07-04 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
4BUD	Crystal structure of human tankyrase 2 in complex with 2-(4-tert- butylphenyl)-1,4-dihydroquinazolin-4-one 分子名称: 2-(4-tert-butylphenyl)-1,4-dihydroquinazolin-4-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2013-06-20 公開日 2013-10-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Para-Substituted 2-Phenyl-3,4-Dihydroquinazolin-4-Ones as Potent and Selective Tankyrase Inhibitors. Chemmedchem, 8, 2013
6SOS	Engineered streptavidin variant (ENAGY) in complex with the Twin-Strep-tag peptide 分子名称: Streptavidin, Twin-Strep-tag peptide 著者 Skerra, A, Eichinger, A. 登録日 2019-08-29 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Role of Changing Loop Conformations in Streptavidin Versions Engineered for High-affinity Binding of the Strep-tag II Peptide. J.Mol.Biol., 433, 2021
7L21	Pyruvate Kinase M2 mutant-N70D 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... 著者 Nandi, S, Dey, M. 登録日 2020-12-16 公開日 2021-12-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Identification of residues involved in allosteric signal transmission from amino acid binding site of pyruvate kinase muscle isoform 2. Plos One, 18, 2023
7EYI	Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation 分子名称: BORIC ACID, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... 著者 Yang, Y, Shi, Y.Y. 登録日 2021-05-31 公開日 2021-09-01 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
4CBR	X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM) 分子名称: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SERINE--PYRUVATE AMINOTRANSFERASE 著者 Yunta, C, Albert, A. 登録日 2013-10-16 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase. Biochem.J., 462, 2014
8ALZ	Cryo-EM structure of ASCC3 in complex with ASC1 分子名称: Activating signal cointegrator 1, Activating signal cointegrator 1 complex subunit 3, ZINC ION 著者 Jia, J, Hilal, T, Loll, B, Wahl, M.C. 登録日 2022-08-01 公開日 2023-03-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure of ASCC3 in complex with ASC1 Nat Commun, 2023
6GG4	Crystal structure of M2 PYK in complex with Phenyalanine. 分子名称: PHENYLALANINE, PHOSPHATE ION, POTASSIUM ION, ... 著者 McNae, I.W, Yuan, M, Walkinshaw, M.D. 登録日 2018-05-02 公開日 2018-05-23 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor. Biochem. J., 475, 2018

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