4CBR
X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM)
Summary for 4CBR
Entry DOI | 10.2210/pdb4cbr/pdb |
Related | 4CBS |
Descriptor | SERINE--PYRUVATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transferase, primary hiperoxaluria type i |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Peroxisome: P21549 |
Total number of polymer chains | 1 |
Total formula weight | 43485.21 |
Authors | Yunta, C.,Albert, A. (deposition date: 2013-10-16, release date: 2014-07-09, Last modification date: 2023-12-20) |
Primary citation | Mesa-Torres, N.,Yunta, C.,Fabelo-Rosa, I.,Gonzalez-Rubio, J.M.,Sanchez-Ruiz, J.M.,Salido, E.,Albert, A.,Pey, A.L. The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase. Biochem.J., 462:453-, 2014 Cited by PubMed: 24957194DOI: 10.1042/BJ20140250 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report