4CBR
X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE--PYRUVATE AMINOTRANSFERASE | polymer | 392 | 43146.0 | 1 | UniProt (P21549) Pfam (PF00266) | HOMO SAPIENS (HUMAN) | SPT, ALANINE--GLYOXYLATE AMINOTRANSFERASE, AGT, ALANINE GLY OXYLATE AMINOTRANSFERASE |
| 2 | B (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 1 - 392 (UniProt: P21549)
| PDB | External Database | Details |
|---|---|---|
| His 48 | Ser 48 | engineered mutation |
| Glu 52 | Asp 52 | engineered mutation |
| Met 340 | Ile 340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43146.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 339.2 | |
| All* | Total formula weight | 43485.2 |
