PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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6L2E	Crystal structure of a cupin protein (tm1459, H52A mutant) in copper (Cu) substituted form 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, Cupin_2 domain-containing protein 著者 Fujieda, N, Ichihashi, H, Nishikawa, Y, Kurisu, G, Itoh, S. 登録日 2019-10-03 公開日 2020-04-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.201 Å) 主引用文献 Cupin Variants as a Macromolecular Ligand Library for Stereoselective Michael Addition of Nitroalkanes. Angew.Chem.Int.Ed.Engl., 59, 2020
1EIN	THE STRUCTURAL ORIGINS OF INTERFACIAL ACTIVATION IN THERMOMYCES (HUMICOLA) LANUGINOSA LIPASE 分子名称: DIUNDECYL PHOSPHATIDYL CHOLINE, LIPASE 著者 Brozozowski, A.M, Savage, H. 登録日 2000-02-26 公開日 2000-12-20 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase. Biochemistry, 39, 2000
6LH7	Crystal Structure of Vibrio cholerae Methionine Aminopeptidase with Partially Occupied Metals 分子名称: GLYCEROL, Methionine aminopeptidase, NICKEL (II) ION, ... 著者 Pillalamarri, V, Addlagatta, A. 登録日 2019-12-06 公開日 2020-12-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.473 Å) 主引用文献 Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp. Eur.J.Med.Chem., 209, 2020
6L34	Crystal structure of the HMG domain of human FACT complex subunit SSRP1 分子名称: FACT complex subunit SSRP1 著者 Li, H.Y, Hu, T.T, Dou, Y.S, Su, D. 登録日 2019-10-09 公開日 2020-10-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.996 Å) 主引用文献 Crystal structure of the HMG domain of human FACT complex subunit SSRP1 To Be Published
3VNZ	Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid 分子名称: GLYCEROL, PHOSPHATE ION, beta-D-glucopyranuronic acid, ... 著者 Momma, M, Fujimoto, Z, Michikawa, M, Ichinose, H, Yoshida, M, Kotake, Y, Biely, P, Tsumuraya, Y, Kaneko, S. 登録日 2012-01-18 公開日 2012-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and biochemical characterization of glycoside hydrolase family 79 beta-glucuronidase from Acidobacterium capsulatum J.Biol.Chem., 287, 2012
6L4R	Crystal structure of Enterovirus D68 RdRp 分子名称: RdRp 著者 Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D. 登録日 2019-10-21 公開日 2020-06-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.147 Å) 主引用文献 Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel. J.Struct.Biol., 211, 2020
6LJ0	Crystal structure of NDM-1 in complex with D-captopril derivative wss02122 分子名称: (2R)-1-[(2S)-2-methyl-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid, Metallo-beta-lactamase type 2, ZINC ION 著者 Zhang, H, Ma, G. 登録日 2019-12-13 公開日 2020-12-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors. Bioorg.Med.Chem., 29, 2020
6L50	Crystal structure of Zika NS2B-NS3 protease with compound 16 分子名称: 2-sulfanylidene-1,3-thiazolidin-4-one, NS3 protease, Serine protease subunit NS2B 著者 Quek, J.P. 登録日 2019-10-21 公開日 2020-07-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease. Antiviral Res., 175, 2020
1EKQ	CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP 分子名称: HYDROXYETHYLTHIAZOLE KINASE 著者 Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E. 登録日 2000-03-09 公開日 2000-08-09 最終更新日 2014-11-12 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution. Biochemistry, 39, 2000
4UQ6	Electron density map of GluA2em in complex with LY451646 and glutamate 分子名称: GLUTAMATE RECEPTOR 2, GLUTAMIC ACID 著者 Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S. 登録日 2014-06-20 公開日 2014-08-13 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (12.8 Å) 主引用文献 Structural Mechanism of Glutamate Receptor Activation and Desensitization Nature, 514, 2014
4UFZ	Synthesis of Novel NAD Dependant DNA Ligase Inhibitors via Negishi Cross-Coupling: Development of SAR and Resistance Studies 分子名称: 1-(2,4-dimethylbenzyl)-6-oxo-1,6-dihydropyridine-3-carboxamide, 5,7-bis(azanyl)-2-tert-butyl-4-(1,3-thiazol-2-yl)pyrido[2,3-d]pyrimidine-6-carbonitrile, DNA LIGASE 著者 Murphy-Benenato, K.E, Boriack-Sjodin, P.A, Martinez-Botella, G, Carcanague, D, Gingipali, L, Gowravaram, M, Harang, J, Hale, M, Ioannidis, G, Jahic, H, Johnstone, M, Kutschke, A, Laganas, V.A, Loch, J, Oguto, H, Patel, S.J. 登録日 2015-03-20 公開日 2015-10-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Negishi Cross-Coupling Enabled Synthesis of Novel Nad(+)-Dependent DNA Ligase Inhibitors and Sar Development. Bioorg.Med.Chem.Lett., 25, 2015
4UH1	Structure of rat neuronal nitric oxide synthase heme domain in complex with N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3- yl)-N1,N2-dimethylethane-1,2-diamine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)-N1,N2-dimethylethane-1,2-diamine, ... 著者 Li, H, Poulos, T.L. 登録日 2015-03-23 公開日 2015-07-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 2-Aminopyridines with a Truncated Side Chain to Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity. J.Med.Chem., 58, 2015
1EL9	COMPLEX OF MONOMERIC SARCOSINE OXIDASE WITH THE INHIBITOR [METHYLTHIO]ACETATE 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ... 著者 Wagner, M.A, Trickey, P, Chen, Z.-W, Mathews, F.S, Jorns, M.S. 登録日 2000-03-13 公開日 2000-12-06 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Monomeric sarcosine oxidase: 1. Flavin reactivity and active site binding determinants. Biochemistry, 39, 2000
3VZT	Crystal Structure of outer membrane protein PorB from Neisseria meningitidis 分子名称: CESIUM ION, outer membrane protein 著者 Tanabe, M, Iverson, T.M. 登録日 2012-10-15 公開日 2012-11-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. Proc.Natl.Acad.Sci.USA, 107, 2010
6LJX	Crystal structure of human FABP4 in complex with a novel inhibitor 分子名称: 2-phenylazanylbenzoic acid, Fatty acid-binding protein, adipocyte 著者 Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
1ELT	STRUCTURE OF NATIVE PANCREATIC ELASTASE FROM NORTH ATLANTIC SALMON AT 1.61 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, ELASTASE 著者 Berglund, G.I, Smalaas, A.O. 登録日 1995-01-02 公開日 1996-01-01 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structure of native pancreatic elastase from North Atlantic salmon at 1.61 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
1EMR	CRYSTAL STRUCTURE OF HUMAN LEUKEMIA INHIBITORY FACTOR (LIF) 分子名称: LEUKEMIA INHIBITORY FACTOR 著者 Robinson, R.C, Heath, J.K, Hawkins, N, Samal, B, Jones, E.Y, Betzel, C. 登録日 2000-03-17 公開日 2001-03-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Species Variation in Receptor Binding Site Revealed by the Medium Resolution X-ray Structure of Human Leukemia Inhibitory Factor to be published
1ENT	X-RAY ANALYSES OF ASPARTIC PROTEINASES. THE THREE-DIMENSIONAL STRUCTURE AT 2.1 ANGSTROMS RESOLUTION OF ENDOTHIAPEPSIN 分子名称: ENDOTHIAPEPSIN, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-{(1S)-1-[(R)-hydroxy(2-{[(2S)-2-methylbutyl]amino}-2-oxoethyl)phosphoryl]-3-methylbutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION 著者 Blundell, T.L, Dealwis, C.G. 登録日 1992-03-11 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin. J.Mol.Biol., 211, 1990
4UPJ	HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U097410 [4-HYDROXY-3-[1-[3-[[[[(TERT-BUTYLOXYCARBONYL) AMINOMETHYL]CARBONYL]AMINO]PHENYL]PROPYL]COUMARIN 分子名称: ({3-[1-(4-HYDROXY-2-OXO-2H-CHROMEN-3-YL)-PROPYL]-PHENYLCARBAMOYL}-METHYL)-CARBAMIC ACID TERT-BUTYL ESTER, HIV-2 PROTEASE 著者 Watenpaugh, K.D, Mulichak, A.M, Janakiraman, M.N. 登録日 1996-03-04 公開日 1996-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J.Med.Chem., 38, 1995
6L46	High-resolution neutron and X-ray joint refined structure of copper-containing nitrite reductase from Geobacillus thermodenitrificans 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, COPPER (II) ION, ... 著者 Fukuda, Y, Hirano, Y, Kusaka, K, Inoue, T, Tamada, T. 登録日 2019-10-16 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 NEUTRON DIFFRACTION (1.3 Å), X-RAY DIFFRACTION 主引用文献 High-resolution neutron crystallography visualizes an OH-bound resting state of a copper-containing nitrite reductase. Proc.Natl.Acad.Sci.USA, 117, 2020
1EOI	CRYSTAL STRUCTURE OF ACID PHOSPHATASE FROM ESCHERICHIA BLATTAE COMPLEXED WITH THE TRANSITION STATE ANALOG MOLYBDATE 分子名称: ACID PHOSPHATASE, MOLYBDATE ION 著者 Ishikawa, K, Mihara, Y, Gondoh, K, Suzuki, E, Asano, Y. 登録日 2000-03-23 公開日 2001-03-23 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray structures of a novel acid phosphatase from Escherichia blattae and its complex with the transition-state analog molybdate. EMBO J., 19, 2000
6L4L	Crystal structure of S. aureus CntK in inactive state 分子名称: 1,2-ETHANEDIOL, Diaminopimelate epimerase 著者 Ju, Y, Luo, S, Zhou, H. 登録日 2019-10-18 公開日 2020-10-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of S. aureus CntK in inactive state To Be Published
1EPA	STRUCTURE OF THE EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN AT 2.1 ANGSTROMS RESOLUTION 分子名称: EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN 著者 Newcomer, M.E. 登録日 1993-06-15 公開日 1994-07-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the epididymal retinoic acid binding protein at 2.1 A resolution. Structure, 1, 1993
1EPV	ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM D-CYCLOSERINE 分子名称: ALANINE RACEMASE, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE 著者 Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D. 登録日 2000-03-29 公開日 2003-01-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A side reaction of alanine racemase: transamination of cycloserine. Biochemistry, 42, 2003
6L59	Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with CIT, Mg and ATP binding at allosteric site and Mg, ATP binding at active site. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ... 著者 Sun, P, Ding, J. 登録日 2019-10-22 公開日 2020-04-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.254 Å) 主引用文献 Molecular mechanism of the dual regulatory roles of ATP on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 10, 2020

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