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3A99
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Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase pim-1
著者Morishita, D, Takami, M, Yoshikawa, S, Katayama, R, Sato, S, Kukimoto-Niino, M, Umehara, T, Shirouzu, M, Sekimizu, K, Yokoyama, S, Fujita, N.
登録日2009-10-22
公開日2010-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
J.Biol.Chem., 286, 2011
1Y7C
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BU of 1y7c by Molmil
T-To-T(High) quaternary transitions in human hemoglobin: betaP100A deoxy low-salt (1 test set)
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Kavanaugh, J.S, Rogers, P.H, Arnone, A.
登録日2004-12-08
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions.
Biochemistry, 44, 2005
1KWZ
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BU of 1kwz by Molmil
Rat mannose protein A (H189V) complexed with Man-a13-Man
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN A, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
1KXO
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BU of 1kxo by Molmil
ENGINEERED LIPOCALIN DIGA16 : APO-FORM
分子名称: DigA16
著者Korndoerfer, I.P, Skerra, A.
登録日2002-02-01
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mechanism of specific ligand recognition by a lipocalin tailored for the complexation of digoxigenin.
J.Mol.Biol., 330, 2003
1Y45
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T-To-T(high) quaternary transitions in human hemoglobin: betaP36A deoxy low-salt (10 test sets)
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Kavanaugh, J.S, Rogers, P.H, Arnone, A.
登録日2004-11-30
公開日2004-12-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions.
Biochemistry, 44, 2005
1Y4P
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BU of 1y4p by Molmil
T-To-T(high) quaternary transitions in human hemoglobin: betaW37E deoxy low-salt (10 test sets)
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Kavanaugh, J.S, Rogers, P.H, Arnone, A.
登録日2004-12-01
公開日2004-12-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions.
Biochemistry, 44, 2005
1Y85
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T-To-T(High) quaternary transitions in human hemoglobin: desHIS146beta deoxy low-salt
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Kavanaugh, J.S, Rogers, P.H, Arnone, A.
登録日2004-12-10
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions.
Biochemistry, 44, 2005
1Y8K
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BU of 1y8k by Molmil
Horse methemoglobin low salt, PH 7.0 (88% relative humidity)
分子名称: Hemoglobin alpha chains, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Sankaranarayanan, R, Biswal, B.K, Vijayan, M.
登録日2004-12-13
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A new relaxed state in horse methemoglobin characterized by crystallographic studies.
Proteins, 60, 2005
1KVA
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BU of 1kva by Molmil
E. COLI RIBONUCLEASE HI D134A MUTANT
分子名称: RIBONUCLEASE H
著者Kashiwagi, T, Jeanteur, D, Haruki, M, Katayanagi, K, Kanaya, S, Morikawa, K.
登録日1996-10-04
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
2ED8
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BU of 2ed8 by Molmil
Solution structure of the second fibronectin type III domain of human Netrin receptor DCC
分子名称: Netrin receptor DCC
著者Tochio, N, Koshiba, S, Tomizawa, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-14
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second fibronectin type III domain of human Netrin receptor DCC
To be Published
2EDY
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BU of 2edy by Molmil
Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F
分子名称: Receptor-type tyrosine-protein phosphatase F
著者Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-15
公開日2007-08-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structures of the fn3 domain of human receptor-type tyrosine-protein phosphatase F
To be Published
1KWV
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Rat mannose binding protein A complexed with a-Me-GlcNAc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-01-30
公開日2002-07-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
1HTE
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BU of 1hte by Molmil
X-RAY CRYSTALLOGRAPHIC STUDIES OF A SERIES OF PENICILLIN-DERIVED ASYMMETRIC INHIBITORS OF HIV-1 PROTEASE
分子名称: (2R,4S)-2-[(R)-BENZYLCARBAMOYL-PHENYLACETYL-METHYL]-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, HIV-1 PROTEASE
著者Jhoti, H, Wonacott, A, Murray-Rust, P.
登録日1994-04-29
公開日1994-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray crystallographic studies of a series of penicillin-derived asymmetric inhibitors of HIV-1 protease.
Biochemistry, 33, 1994
2E9N
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BU of 2e9n by Molmil
Structure of h-CHK1 complexed with A767085
分子名称: 3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE, Serine/threonine-protein kinase Chk1
著者Park, C.
登録日2007-01-26
公開日2008-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.
Bioorg.Med.Chem., 15, 2007
1Y8W
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BU of 1y8w by Molmil
T-To-T(High) quaternary transitions in human hemoglobin: alphaR92A oxy (2mM IHP, 20% PEG) (10 test sets)
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, OXYGEN MOLECULE, ...
著者Kavanaugh, J.S, Rogers, P.H, Arnone, A.
登録日2004-12-13
公開日2005-01-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic evidence for a new ensemble of ligand-induced allosteric transitions in hemoglobin: the T-to-T(high) quaternary transitions.
Biochemistry, 44, 2005
1HIT
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BU of 1hit by Molmil
Receptor binding redefined by a structural switch in a mutant Human Insulin
分子名称: INSULIN
著者Hua, Q.X, Kochoyan, M, Weiss, M.A.
登録日1992-02-28
公開日1994-01-31
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献Receptor binding redefined by a structural switch in a mutant human insulin.
Nature, 354, 1991
2E9S
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BU of 2e9s by Molmil
human neuronal Rab6B in three intermediate forms
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NITRATE ION, ...
著者Vellieux, F.M, Tcherniuk, S, Garcia-Saez, I, Kozielski, F.
登録日2007-01-26
公開日2008-01-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献3D structure of human neuronal Rab6B in three intermediate forms
To be Published
1HML
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BU of 1hml by Molmil
ALPHA_LACTALBUMIN POSSESSES A DISTINCT ZINC BINDING SITE
分子名称: ALPHA-LACTALBUMIN, CALCIUM ION, SULFATE ION, ...
著者Ren, J, Stuart, D.I, Acharya, K.R.
登録日1994-09-29
公開日1995-01-26
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Alpha-lactalbumin possesses a distinct zinc binding site.
J.Biol.Chem., 268, 1993
1Y94
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Crystal structure of the G16S/N17T/P19A/S20A/N67D Variant Of Bovine seminal Ribonuclease
分子名称: Seminal ribonuclease
著者Picone, D, Di Fiore, A, Ercole, C, Franzese, M, Sica, F, Tomaselli, S, Mazzarella, L.
登録日2004-12-14
公開日2004-12-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Role of the Hinge Loop in Domain Swapping: THE SPECIAL CASE OF BOVINE SEMINAL RIBONUCLEASE.
J.Biol.Chem., 280, 2005
1HKY
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BU of 1hky by Molmil
Solution structure of a PAN module from Eimeria tenella
分子名称: MICRONEME PROTEIN 5 PRECURSOR
著者Brown, P.J, Mulvey, D, Potts, J.R, Tomley, F.M, Campbell, I.D.
登録日2002-10-03
公開日2002-10-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of a Pan Module from the Apicomplexan Parasite Eimeria Tenella
J.Struct.Funct.Genom., 4, 2003
2EB9
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Crystal Structure of Cu(II)(Sal-Leu)/apo-Myoglobin
分子名称: (N-SALICYLIDEN-L-LEUCINATO)-COPPER(II), GLYCEROL, Myoglobin, ...
著者Abe, S, Okazaki, S, Ueno, T, Hikage, T, Suzuki, A, Yamane, T, Watanabe, Y.
登録日2007-02-07
公開日2007-07-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design and Structure Analysis of Artificial Metalloproteins: Selective Coordination of His64 to Copper Complexes with Square-Planar Structure in the apo-Myoglobin Scaffold
Inorg.Chem., 46, 2007
2EBT
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Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5
分子名称: Krueppel-like factor 5, ZINC ION
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-09
公開日2008-02-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5
To be Published
2QC6
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Protein kinase CK2 in complex with DBC
分子名称: 3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE, Casein kinase II subunit alpha
著者Battistutta, R.
登録日2007-06-19
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.
J.Med.Chem., 51, 2008
2ECB
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BU of 2ecb by Molmil
The solution structure of the third homeobox domain of human zinc fingers and homeoboxes protein
分子名称: Zinc fingers and homeoboxes protein 1
著者Ohnishi, S, Tochio, N, Sasagawa, A, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-13
公開日2007-02-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the third homeobox domain of human Zinc fingers and homeoboxes protein
To be Published
1YI4
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Structure of Pim-1 bound to adenosine
分子名称: ADENOSINE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Jacobs, M.D, Black, J, Futer, O, Swenson, L, Hare, B, Fleming, M, Saxena, K.
登録日2005-01-11
公開日2005-01-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.
J.Biol.Chem., 280, 2005

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