1YI4
Structure of Pim-1 bound to adenosine
Summary for 1YI4
Entry DOI | 10.2210/pdb1yi4/pdb |
Related | 1YHS 1YI3 |
Descriptor | Proto-oncogene serine/threonine-protein kinase Pim-1, ADENOSINE (3 entities in total) |
Functional Keywords | protein kinase, proto oncogene, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 31941.13 |
Authors | Jacobs, M.D.,Black, J.,Futer, O.,Swenson, L.,Hare, B.,Fleming, M.,Saxena, K. (deposition date: 2005-01-11, release date: 2005-01-25, Last modification date: 2011-07-13) |
Primary citation | Jacobs, M.D.,Black, J.,Futer, O.,Swenson, L.,Hare, B.,Fleming, M.,Saxena, K. Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002. J.Biol.Chem., 280:13728-13734, 2005 Cited by PubMed: 15657054DOI: 10.1074/jbc.M413155200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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