7AO8
| Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex | 分子名称: | Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... | 著者 | Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. | 登録日 | 2020-10-14 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
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7AE1
| Cryo-EM structure of human RNA Polymerase III elongation complex 1 | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | 登録日 | 2020-09-17 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7AE3
| Cryo-EM structure of human RNA Polymerase III elongation complex 3 | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | 登録日 | 2020-09-17 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7AEA
| Cryo-EM structure of human RNA Polymerase III elongation complex 2 | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | 登録日 | 2020-09-17 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7A6H
| Cryo-EM structure of human apo RNA Polymerase III | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. | 登録日 | 2020-08-25 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
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7YQ8
| Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | 著者 | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | 登録日 | 2022-08-05 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun, 14, 2023
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7D58
| cryo-EM structure of human RNA polymerase III in elongating state | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | 登録日 | 2020-09-25 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
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7D59
| cryo-EM structure of human RNA polymerase III in apo state | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | 登録日 | 2020-09-25 | 公開日 | 2021-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
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7FJJ
| human Pol III pre-termination complex | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Hou, H, Xu, Y. | 登録日 | 2021-08-04 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
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7FJI
| human Pol III elongation complex | 分子名称: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | 著者 | Hou, H, Xu, Y. | 登録日 | 2021-08-04 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
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5Z58
| Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5HO4
| Crystal structure of hnRNPA2B1 in complex with 10-mer RNA | 分子名称: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3') | 著者 | Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B. | 登録日 | 2016-01-19 | 公開日 | 2017-02-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
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2XSZ
| The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2 | 著者 | Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A. | 登録日 | 2010-10-01 | 公開日 | 2011-10-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex. J.Struct.Biol., 176, 2011
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2YYN
| Crystal structure of human bromodomain protein | 分子名称: | Transcription intermediary factor 1-alpha | 著者 | Kishishita, S, Uchikubo-Kamo, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-04-30 | 公開日 | 2008-05-06 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human bromodomain protein To be Published
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2G50
| The location of the allosteric amino acid binding site of muscle pyruvate kinase. | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ALANINE, ... | 著者 | Holyoak, T, Williams, R, Fenton, A.W. | 登録日 | 2006-02-22 | 公開日 | 2006-05-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase. Biochemistry, 45, 2006
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2G4D
| Crystal structure of human SENP1 mutant (C603S) in complex with SUMO-1 | 分子名称: | SENP1 protein, Small ubiquitin-related modifier 1 | 著者 | Xu, Z, Chau, S.F, Lam, K.H, Au, S.W.N. | 登録日 | 2006-02-22 | 公開日 | 2006-10-17 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease Biochem.J., 398, 2006
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8HK1
| The cryo-EM structure of human pre-17S U2 snRNP | 分子名称: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | 著者 | Zhang, X, Zhan, X, Shi, Y. | 登録日 | 2022-11-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
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8IUH
| RNA polymerase III pre-initiation complex open complex 1 | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... | 著者 | Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. | 登録日 | 2023-03-24 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
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6ZH6
| Cryo-EM structure of DNA-PKcs:Ku80ct194 | 分子名称: | DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5 | 著者 | Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. | 登録日 | 2020-06-21 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
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1PGZ
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6JLB
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2ASQ
| Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM) | 分子名称: | Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1 | 著者 | Song, J, Zhang, Z, Hu, W, Chen, Y. | 登録日 | 2005-08-23 | 公開日 | 2005-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation J.Biol.Chem., 280, 2005
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7R5K
| Human nuclear pore complex (constricted) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-06-22 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
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7R5J
| Human nuclear pore complex (dilated) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-09-21 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (50 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
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6QU1
| Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution. | 分子名称: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION | 著者 | Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-02-26 | 公開日 | 2019-07-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 2019
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