PDB: 5425 件ウェブページステータス検索Chemie searchBIRD

---

7AO8	Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex 分子名称: Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... 著者 Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. 登録日 2020-10-14 公開日 2020-11-11 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
7AE1	Cryo-EM structure of human RNA Polymerase III elongation complex 1 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. 登録日 2020-09-17 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AE3	Cryo-EM structure of human RNA Polymerase III elongation complex 3 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. 登録日 2020-09-17 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7AEA	Cryo-EM structure of human RNA Polymerase III elongation complex 2 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. 登録日 2020-09-17 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7A6H	Cryo-EM structure of human apo RNA Polymerase III 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. 登録日 2020-08-25 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
7YQ8	Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide 分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... 著者 Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. 登録日 2022-08-05 公開日 2024-01-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun, 14, 2023
7D58	cryo-EM structure of human RNA polymerase III in elongating state 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. 登録日 2020-09-25 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
7D59	cryo-EM structure of human RNA polymerase III in apo state 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. 登録日 2020-09-25 公開日 2021-02-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into transcriptional regulation of human RNA polymerase III. Nat.Struct.Mol.Biol., 28, 2021
7FJJ	human Pol III pre-termination complex 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Hou, H, Xu, Y. 登録日 2021-08-04 公開日 2021-10-27 最終更新日 2021-11-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
7FJI	human Pol III elongation complex 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Hou, H, Xu, Y. 登録日 2021-08-04 公開日 2021-10-27 最終更新日 2021-11-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine. Nat Commun, 12, 2021
5Z58	Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. 登録日 2018-01-17 公開日 2018-09-19 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
5HO4	Crystal structure of hnRNPA2B1 in complex with 10-mer RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3') 著者 Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B. 登録日 2016-01-19 公開日 2017-02-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
2XSZ	The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II 分子名称: ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2 著者 Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A. 登録日 2010-10-01 公開日 2011-10-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex. J.Struct.Biol., 176, 2011
2YYN	Crystal structure of human bromodomain protein 分子名称: Transcription intermediary factor 1-alpha 著者 Kishishita, S, Uchikubo-Kamo, T, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-30 公開日 2008-05-06 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human bromodomain protein To be Published
2G50	The location of the allosteric amino acid binding site of muscle pyruvate kinase. 分子名称: 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ALANINE, ... 著者 Holyoak, T, Williams, R, Fenton, A.W. 登録日 2006-02-22 公開日 2006-05-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase. Biochemistry, 45, 2006
2G4D	Crystal structure of human SENP1 mutant (C603S) in complex with SUMO-1 分子名称: SENP1 protein, Small ubiquitin-related modifier 1 著者 Xu, Z, Chau, S.F, Lam, K.H, Au, S.W.N. 登録日 2006-02-22 公開日 2006-10-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease Biochem.J., 398, 2006
8HK1	The cryo-EM structure of human pre-17S U2 snRNP 分子名称: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... 著者 Zhang, X, Zhan, X, Shi, Y. 登録日 2022-11-24 公開日 2023-03-08 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
8IUH	RNA polymerase III pre-initiation complex open complex 1 分子名称: DNA (81-MER), DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ... 著者 Hou, H, Jin, Q, Ren, Y, Wang, Q, Xu, Y. 登録日 2023-03-24 公開日 2023-05-24 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of the SNAPc-bound RNA polymerase III preinitiation complex. Cell Res., 33, 2023
6ZH6	Cryo-EM structure of DNA-PKcs:Ku80ct194 分子名称: DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5 著者 Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. 登録日 2020-06-21 公開日 2020-10-21 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
1PGZ	Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI) 分子名称: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1 著者 Myers, J.C, Moore, S.A, Shamoo, Y. 登録日 2003-05-28 公開日 2003-11-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures J.Biol.Chem., 278, 2003
6JLB	Crystal structure of lamin A/C fragment and assembly mechanisms of intermediate filaments 分子名称: Lamin A/C 著者 Ahn, J, Jo, I, Ha, N.C. 登録日 2019-03-04 公開日 2019-09-11 実験手法 X-RAY DIFFRACTION (3.205 Å) 主引用文献 Structural basis for lamin assembly at the molecular level. Nat Commun, 10, 2019
2ASQ	Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM) 分子名称: Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1 著者 Song, J, Zhang, Z, Hu, W, Chen, Y. 登録日 2005-08-23 公開日 2005-10-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation J.Biol.Chem., 280, 2005
7R5K	Human nuclear pore complex (constricted) 分子名称: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... 著者 Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. 登録日 2022-02-10 公開日 2022-06-22 最終更新日 2022-06-29 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
7R5J	Human nuclear pore complex (dilated) 分子名称: Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... 著者 Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. 登録日 2022-02-10 公開日 2022-09-21 最終更新日 2022-12-21 実験手法 ELECTRON MICROSCOPY (50 Å) 主引用文献 AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
6QU1	Crystal structure of the KAP1 RBCC domain in complex with the SMARCAD1 CUE1 domain at 3.7 angstrom resolution. 分子名称: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1, Transcription intermediary factor 1-beta,Transcription intermediary factor 1-beta, ZINC ION 著者 Newman, J.A, Aitkenhead, H, Gavard, A, Lim, M, Williams, H.L, Svejstrup, J.Q, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2019-02-26 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin. Structure, 2019

<12345678910111213141516>