PDB: 153 件ウェブページステータス検索Chemie searchBIRD

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6X2W	Crystal Structure of PKINES peptide bound to CRM1(E571K) 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M. 登録日 2020-05-21 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2U	Crystal Structure of PKINES peptide bound to CRM1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M. 登録日 2020-05-21 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2S	Crystal Structure of Mek1(NQ)NES peptide bound to CRM 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.496 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2M	Crystal Structure of unliganded CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2P	Crystal Structure of the Mek1NES peptide bound to CRM1 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2V	Crystal Structure of PKI(DE)NES peptide bound to CRM1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Baumhardt, J.M. 登録日 2020-05-21 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.822 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2O	Crystal Structure of unliganded CRM1(E571K)-Ran-RanBP1 分子名称: Exportin-1, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.551 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2X	Crystal Structure of Mek1NES peptide bound to CRM1(E571K) 分子名称: Dual specificity mitogen-activated protein kinase kinase 1, Exportin-1, GLYCEROL, ... 著者 Baumhardt, J.M. 登録日 2020-05-21 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.458 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2Y	Crystal Structure of mDia2NES peptide bound to CRM1(E571K) 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Baumhardt, J.M. 登録日 2020-05-21 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
6X2R	Crystal Structure of the 4E-TNES peptide bound to CRM1 分子名称: Eukaryotic translation initiation factor 4E transporter, Exportin-1, GLYCEROL, ... 著者 Baumhardt, J.M. 登録日 2020-05-20 公開日 2020-07-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
4GMX	Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-16 公開日 2012-10-17 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia. Blood, 120, 2012
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAY	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4GPT	Crystal structure of KPT251 in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 2-(2-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}ethyl)-1,3,4-oxadiazole, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-08-21 公開日 2012-09-05 最終更新日 2013-01-23 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia, 27, 2013
4HAX	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1(K579A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAV	Crystal structure of CRM1 inhibitor Anguinomycin A in complex with CRM1-Ran-RanBP1 分子名称: Anguinomycin A, bound form, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB2	Crystal structure of CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAU	Crystal structure of CRM1 inhibitor Ratjadone A in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAW	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
5TQC	Crystal structure of transport factor karyopherin-beta 2 in complex with the PY-NLS of ribosomal protein L4 (RpL4) 分子名称: 60S ribosomal protein L4-like protein, Transportin-1,Transportin-1 著者 Huber, F.M, Hoelz, A. 登録日 2016-10-23 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Molecular basis for protection of ribosomal protein L4 from cellular degradation. Nat Commun, 8, 2017
5UWI	Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1 分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... 著者 Fung, H.Y.J, Chook, Y.M. 登録日 2017-02-21 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.143 Å) 主引用文献 Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals. Elife, 6, 2017

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