PDB: 149 件ウェブページステータス検索Chemie searchBIRD

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7B0Y	Structure of a transcribing RNA polymerase II-U1 snRNP complex 分子名称: 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ... 著者 Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P. 登録日 2020-11-23 公開日 2021-01-13 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of a transcribing RNA polymerase II-U1 snRNP complex. Science, 371, 2021
7A5P	Human C Complex Spliceosome - Medium-resolution PERIPHERY 分子名称: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ... 著者 Bertram, K, Kastner, B. 登録日 2020-08-21 公開日 2020-10-14 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. Mol.Cell, 80, 2020
7B9V	Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound 分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... 著者 Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. 登録日 2020-12-14 公開日 2021-03-10 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for conformational equilibrium of the catalytic spliceosome. Mol.Cell, 81, 2021
5GAO	Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP 分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ... 著者 Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
6Y53	human 17S U2 snRNP low resolution part 分子名称: HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... 著者 Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. 登録日 2020-02-24 公開日 2020-06-17 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
6YGC	Crystal structure of the NatC complex bound to Arl3 peptide and CoA 分子名称: ADP-ribosylation factor-like protein 3, CHLORIDE ION, COENZYME A, ... 著者 Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. 登録日 2020-03-27 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.994 Å) 主引用文献 Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
6Y5Q	human 17S U2 snRNP 分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... 著者 Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. 登録日 2020-02-25 公開日 2020-06-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
6YGB	Crystal structure of the NatC complex bound to CoA 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... 著者 Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. 登録日 2020-03-27 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.451 Å) 主引用文献 Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
6YGA	Crystal structure of the apo NatC complex 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. 登録日 2020-03-27 公開日 2020-10-28 最終更新日 2020-11-18 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
6YGD	Crystal structure of the NatC complex bound to Gag peptide and CoA 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... 著者 Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. 登録日 2020-03-27 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.752 Å) 主引用文献 Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
6J6G	Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom 分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6H	Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom 分子名称: ACT1 pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6J6Q	Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
6QDV	Human post-catalytic P complex spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Fica, S.M, Oubridge, C, Wilkinson, M.E, Newman, A.J, Nagai, K. 登録日 2019-01-03 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science, 363, 2019
6ICZ	Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6ID0	Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6QW6	Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-05 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6QX9	Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Charenton, C, Wilkinson, M.E, Nagai, K. 登録日 2019-03-07 公開日 2019-04-17 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
6ID1	Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
6J6N	Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Bai, R, Yan, C, Lei, J, Shi, Y. 登録日 2019-01-15 公開日 2019-04-24 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching. Cell, 177, 2019
5MQF	Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... 著者 Bertram, K, Hartmuth, K, Kastner, B. 登録日 2016-12-20 公開日 2017-03-22 最終更新日 2018-11-21 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
5MPS	Structure of a spliceosome remodeled for exon ligation 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. 登録日 2016-12-18 公開日 2017-01-18 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
5MQ0	Structure of a spliceosome remodeled for exon ligation 分子名称: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... 著者 Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. 登録日 2016-12-19 公開日 2017-01-18 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.17 Å) 主引用文献 Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
5NRL	Structure of a pre-catalytic spliceosome. 分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... 著者 Plaschka, C, Lin, P.-C, Nagai, K. 登録日 2017-04-24 公開日 2017-05-31 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Structure of a pre-catalytic spliceosome. Nature, 546, 2017
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... 著者 Bertram, K, Kastner, B. 登録日 2017-06-20 公開日 2017-08-16 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017

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