5XA7
 
 | | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-2CA2+ crystals | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, SODIUM ION, ... | | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | | 登録日 | 2017-03-11 | | 公開日 | 2017-05-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump.
Nature, 545, 2017
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5XAB
 | | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2(TG) crystals | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | | 登録日 | 2017-03-11 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump.
Nature, 545, 2017
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5YLV
 | | Crystal structure of the gastric proton pump complexed with SCH28080 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79977775 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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5Y0B
 | | PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | | 分子名称: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | | 著者 | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | | 登録日 | 2017-07-16 | | 公開日 | 2017-08-09 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | | 主引用文献 | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors
Sci Rep, 7, 2017
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5YLU
 | | Crystal structure of the gastric proton pump complexed with vonoprazan | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79988956 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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5ZMV
 | | Crystal structure of the E309A mutant of SR Ca2+-ATPase in E2(TG) | | 分子名称: | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, ... | | 著者 | Ogawa, H, Hirata, A, Tsueda, J, Toyoshima, C. | | 登録日 | 2018-04-06 | | 公開日 | 2018-12-12 | | 最終更新日 | 2018-12-26 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Mechanism of the E2 to E1 transition in Ca2+pump revealed by crystal structures of gating residue mutants.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZMW
 | | Crystal structure of the E309Q mutant of SR Ca2+-ATPase in E2(TG) | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | | 著者 | Ogawa, H, Hirata, A, Tsueda, J, Toyoshima, C. | | 登録日 | 2018-04-06 | | 公開日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanism of the E2 to E1 transition in Ca2+pump revealed by crystal structures of gating residue mutants.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5ZTF
 | | Structure of Ca2+ ATPase | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Inoue, M, Watanabe, S, Inaba, K. | | 登録日 | 2018-05-03 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay.
Cell Rep, 27, 2019
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6JJU
 | | Structure of Ca2+ ATPase | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Inoue, M, Sakuta, N, Watanabe, S, Inaba, K. | | 登録日 | 2019-02-27 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay.
Cell Rep, 27, 2019
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6JXI
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6JXH
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6JXJ
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6JXK
 | | Rb+-bound E2-MgF state of the gastric proton pump (Wild-type) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, MAGNESIUM ION, ... | | 著者 | Abe, K, Irie, K, Yamamoto, K. | | 登録日 | 2019-04-23 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | A single K + -binding site in the crystal structure of the gastric proton pump.
Elife, 8, 2019
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6LN5
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN9
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class2) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN7
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class3) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN8
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class1) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN6
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class2) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LLE
 | | CryoEM structure of SERCA2b WT in E1-2Ca2+-AMPPCP state. | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-23 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LLY
 | | CryoEM structure of SERCA2b WT in E2-BeF3- state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-24 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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8IJM
 | | Cyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP state | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Abe, K. | | 登録日 | 2023-02-27 | | 公開日 | 2023-08-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
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8IJX
 | | Cryo-EM structure of the gastric proton pump with bound DQ-18 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
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8IJV
 | | Cryo-EM structure of the gastric proton pump with bound DQ-02 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[5-chloranyl-2-(4-chlorophenyl)phenyl]methoxy]-N-methyl-but-2-yn-1-amine, ... | | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
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8IJW
 | | Cryo-EM structure of the gastric proton pump with bound DQ-06 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | | 登録日 | 2023-02-28 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures.
Commun Biol, 6, 2023
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8IJL
 | | Cyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADP | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Abe, K. | | 登録日 | 2023-02-27 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding.
Biochim Biophys Acta Mol Cell Res, 1870, 2023
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