PDB: 294 件ウェブページステータス検索Chemie searchBIRD

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3KND	TPX2:importin-alpha complex 分子名称: Importin subunit alpha-2, SULFATE ION, Targeting protein for Xklp2 著者 Stewart, M. 登録日 2009-11-12 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha. J.Biol.Chem., 285, 2010
6WBA	Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex 分子名称: DNA mismatch repair protein Mlh1, Importin subunit alpha-1 著者 de Barros, A.C, da Silva, T.D, Oliveira, H.C, Fukuda, C.A, Fontes, M.R.M. 登録日 2020-03-26 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha. Biochem.J., 478, 2021
5U5P	Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DNA mismatch repair protein Mlh1, Importin subunit alpha-1 著者 Barros, A.C, Takeda, A.A, Dreyer, T.R, Velazquez-Campoy, A, Kobe, B, Fontes, M.R. 登録日 2016-12-07 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.171 Å) 主引用文献 DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway. Biochimie, 146, 2018
5W4E	Importin binding to Tdt NLS peptide 分子名称: GLYCEROL, Importin subunit alpha-1,Importin subunit alpha-1, human DNA repair polymerase Tdt 著者 Pedersen, L.C, London, R. 登録日 2017-06-10 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
6D7M	Crystal structure of the W184R/W231R Importin alpha mutant 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ... 著者 Pedersen, L.C, London, R.E, Gabel, S.A. 登録日 2018-04-25 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
1Y2A	Structure of mammalian importin bound to the non-classical PLSCR1-NLS 分子名称: Importin alpha-2 Subunit, decamer fragment of Phospholipid scramblase 1 著者 Chen, M.-H, Ben-Efraim, I, Mitrousis, G, Walker-Kopp, N, Sims, P.J, Cingolani, G. 登録日 2004-11-22 公開日 2005-02-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha J.Biol.Chem., 280, 2005
3FEY	Crystal structure of the CBC-importin alpha complex. 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 著者 Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. 登録日 2008-12-01 公開日 2009-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
5W41	Zika MR766 NLS in complex with Importin alpha subunit-1 分子名称: Importin subunit alpha-1, ZIKA MR766 NLS 著者 Jeffress, S, Smith, K.M, Forwood, J.K. 登録日 2017-06-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019
5H2X	Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172) 分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1 著者 Hirano, H, Matsuura, Y. 登録日 2016-10-18 公開日 2016-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p J. Mol. Biol., 429, 2017
3SL9	X-ray structure of Beta catenin in complex with Bcl9 分子名称: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ... 著者 Gupta, D, Bienz, M. 登録日 2011-06-24 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3, 2012
1QZ7	Beta-catenin binding domain of Axin in complex with beta-catenin 分子名称: Axin, Beta-catenin 著者 Xing, Y, Clements, W.K, Kimelman, D, Xu, W. 登録日 2003-09-15 公開日 2003-11-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex GENES DEV., 17, 2003
2JDQ	C-terminal domain of influenza A virus polymerase PB2 subunit in complex with human importin alpha5 分子名称: IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Guilligay, D, Mas, P, Boulo, S, Baudin, F, Ruigrok, R.W.H, Hart, D.J, Cusack, S. 登録日 2007-01-11 公開日 2007-02-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Nuclear Import Function of the C- Terminal Domain of Influenza Virus Polymerase Pb2 Subunit Nat.Struct.Mol.Biol., 14, 2007
5KLR	Prototypical P4[R]cNLS 分子名称: Importin subunit alpha-1, Prototypical P4[R]cNLS 著者 Smith, K.M, Forwood, J.K. 登録日 2016-06-25 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting. Biochim Biophys Acta Mol Cell Res, 1865, 2018
7JVO	Importin alpha bound to the C-terminus of ACE2 分子名称: ARG-LYS-LYS-LYS-ASN-LYS-ALA, Importin subunit alpha-1 著者 Forwood, J.K, Cross, E.M, Tsimbalyuk, S. 登録日 2020-08-22 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. Cell Discov, 7, 2021
1BK5	KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE 分子名称: COBALT (II) ION, KARYOPHERIN ALPHA 著者 Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. 登録日 1998-07-14 公開日 1999-01-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
7N9H	Structure of the mammalian importin a1 bound to the TDP-43 NLS 分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43 著者 Doll, S.G, Lokareddy, R.K, Cingolani, G. 登録日 2021-06-17 公開日 2022-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta. Cell Rep, 39, 2022
6BW1	Hendra virus W protein C-terminus in complex with Importin alpha 1 分子名称: Importin subunit alpha-1, Protein W 著者 Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. 登録日 2017-12-14 公開日 2018-07-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
2Z6H	Crystal Structure of Beta-Catenin Armadillo Repeat Region and Its C-Terminal domain 分子名称: Catenin beta-1 著者 Xing, Y, Takemaru, K, Liu, J, Zheng, J, Moon, R, Xu, W. 登録日 2007-08-01 公開日 2008-02-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of a Full-Length beta-Catenin Structure, 16, 2008
6BWA	Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2 分子名称: Importin subunit alpha-3, Protein W 著者 Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. 登録日 2017-12-14 公開日 2018-07-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
5WUN	Crystal structure of mouse importin-alpha1 bound to non-phosphorylated NLS of EBNA1 分子名称: Epstein-Barr nuclear antigen 1, Importin subunit alpha-1 著者 Nakada, R, Hirano, H, Matsuura, Y. 登録日 2016-12-19 公開日 2017-01-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal. Biochem. Biophys. Res. Commun., 484, 2017
8SV0	The crystal structure of the classical binding interface of Importin alpha 2 and nuclear localisation signal sequence in Psittacine siadenovirus core protein VII 分子名称: Importin subunit alpha-1, SODIUM ION, protein VII 著者 Athukorala, A, Sarker, S, Forwood, J.K, Donnelly, C.M. 登録日 2023-05-14 公開日 2023-05-31 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional characterization of nuclear localization signal of pVII protein of psittacine siadenovirus F demonstrates an independent transport of pVII protein into the nucleus To Be Published
2C1M	Nup50:importin-alpha complex 分子名称: IMPORTIN-ALPHA2 SUBUNIT, NUCLEOPORIN 50 KDA 著者 Matsuura, Y, Stewart, M. 登録日 2005-09-16 公開日 2005-11-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nup50/Npap60 Function in Nuclear Protein Import Complex Disassembly and Importin Recycling. Embo J., 24, 2005
5HHG	Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex 分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 著者 Smith, K.M, Forwood, J.K. 登録日 2016-01-11 公開日 2016-05-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. PLoS Pathog., 12, 2016
3UKX	Mouse importin alpha: Bimax2 peptide complex 分子名称: Bimax2 peptide, Importin subunit alpha-2 著者 Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. 登録日 2011-11-10 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha Traffic, 13, 2012
8Z0U	Human beta-catenin crystal structure 分子名称: Catenin beta-1 著者 Tim, F. 登録日 2024-04-10 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal protein human Beta-catenin To Be Published

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