PDB: 292 件ウェブページステータス検索Chemie searchBIRD

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7TMY	Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex 分子名称: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3 著者 Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M. 登録日 2022-01-20 公開日 2023-08-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha. Biochim Biophys Acta Proteins Proteom, 1872, 2023
8SV0	The crystal structure of the classical binding interface of Importin alpha 2 and nuclear localisation signal sequence in Psittacine siadenovirus core protein VII 分子名称: Importin subunit alpha-1, SODIUM ION, protein VII 著者 Athukorala, A, Sarker, S, Forwood, J.K, Donnelly, C.M. 登録日 2023-05-14 公開日 2023-05-31 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional characterization of nuclear localization signal of pVII protein of psittacine siadenovirus F demonstrates an independent transport of pVII protein into the nucleus To Be Published
4ZDU	Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein 分子名称: Importin subunit alpha-1, Peptide from Nucleoprotein 著者 Nakada, R, Hirano, H, Matsuura, Y. 登録日 2015-04-19 公開日 2015-10-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein Sci Rep, 5, 2015
4YJE	Crystal structure of APC-ARM in complexed with Amer1-A1 分子名称: APC membrane recruitment protein 1, Adenomatous polyposis coli protein 著者 Zhang, Z, Xiao, Y, Wu, G. 登録日 2015-03-03 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
4YJL	Crystal structure of APC-ARM in complexed with Amer1-A2 分子名称: 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein 著者 Zhang, Z, Xiao, Y, Wu, G. 登録日 2015-03-03 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
8SG7	Adeno-Associated Virus Bat origin capsid protein basic regions in complex with importin-alpha 2 分子名称: Importin subunit alpha-1, VP1 capsid 著者 Hoad, M, Forwood, J.K. 登録日 2023-04-11 公開日 2023-07-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for nuclear import of bat adeno-associated virus capsid protein. J.Gen.Virol., 105, 2024
6BW1	Hendra virus W protein C-terminus in complex with Importin alpha 1 分子名称: Importin subunit alpha-1, Protein W 著者 Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. 登録日 2017-12-14 公開日 2018-07-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
6BW0	Nipah virus W protein C-terminus in complex with Importin alpha 1 分子名称: Importin subunit alpha-1, Protein W 著者 Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. 登録日 2017-12-14 公開日 2018-07-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
6BWB	Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 分子名称: Importin subunit alpha-3, Protein W 著者 Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. 登録日 2017-12-14 公開日 2018-07-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
8SUD	JC Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-05-12 公開日 2024-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
2YNR	mImp_alphadIBB_B54NLS 分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA 著者 Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. 登録日 2012-10-18 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
2YNS	rImp_alpha_B54NLS 分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA-1A 著者 Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. 登録日 2012-10-18 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals. Plant Cell, 24, 2012
7JJM	Crystal structure of Importin alpha 2 in complex with LSD1 NLS 分子名称: CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
7JJL	Crystal structure of Importin Alpha 3 in complex with human LSD1 NLS 分子名称: Importin subunit alpha-3, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McCuaig, R, Tan, H.Y.A, Hardy, K, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
7JK7	Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant 分子名称: GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A 著者 Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. 登録日 2020-07-27 公開日 2020-08-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
7JVO	Importin alpha bound to the C-terminus of ACE2 分子名称: ARG-LYS-LYS-LYS-ASN-LYS-ALA, Importin subunit alpha-1 著者 Forwood, J.K, Cross, E.M, Tsimbalyuk, S. 登録日 2020-08-22 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication. Cell Discov, 7, 2021
7UMI	Importin a1 bound to Cp183-CTD 分子名称: HBV-NLS, Importin subunit alpha-1 著者 Yang, R, Cingolani, G. 登録日 2022-04-07 公開日 2023-10-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
8Q8K	KI Polyomavirus LTA NLS bound to importin alpha 2 分子名称: Importin subunit alpha-1, Large T antigen 著者 Cross, E.M, Forwood, J.K, Alvisi, G. 登録日 2023-08-18 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
3AU3	Crystal structure of armadillo repeat domain of APC 分子名称: Adenomatous polyposis coli protein 著者 Murayama, K, Kato-Murayama, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-01-28 公開日 2011-11-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68 Structure, 19, 2011
5XZX	Crystal structure of importin-alpha3 bound to the nuclear localization signal of Ran-binding protein 3 分子名称: Importin subunit alpha-3, Ran-binding protein 3 著者 Koyama, M, Matsuura, Y. 登録日 2017-07-14 公開日 2017-08-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of importin-alpha 3 bound to the nuclear localization signal of Ran-binding protein 3 Biochem. Biophys. Res. Commun., 491, 2017
3OQS	Crystal structure of importin-alpha bound to a CLIC4 NLS peptide 分子名称: Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4 著者 Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G. 登録日 2010-09-03 公開日 2011-07-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 Febs J., 278, 2011
5Z8H	APC with an inhibitor 分子名称: Adenomatous polyposis coli protein, GLYCEROL, Peptide inhibitor 著者 Zhang, J, Yang, X.Y, Song, K. 登録日 2018-01-31 公開日 2019-02-06 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 APC with an inhibitor To Be Published
3Q5U	A minimal NLS from human scramblase 4 complexed with importin alpha 分子名称: Importin subunit alpha-2, Phospholipid scramblase 4 著者 Bhardwaj, A, Cingolani, G. 登録日 2010-12-29 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1. J.Biol.Chem., 286, 2011
3QHE	Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68 分子名称: Adenomatous polyposis coli protein, KH domain-containing, RNA-binding, ... 著者 Morishita, E.C.J, Murayama, K, Kato-Murayama, M, Ishizuku-Katsura, Y, Tomabechi, Y, Terada, T, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-01-25 公開日 2011-11-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68 Structure, 19, 2011
4E4V	The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2 著者 Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W. 登録日 2012-03-13 公開日 2013-05-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5283 Å) 主引用文献 The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution. To be Published

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