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2PIZ
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BU of 2piz by Molmil
CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B 2-(3-Guanidino-phenyl)-3-[hydroxy-(3-phenyl-propyl)-phosphinoyl]-propionic acid COMPLEX
分子名称: (2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID, Carboxypeptidase B, ZINC ION
著者Adler, M, Whitlow, M.
登録日2007-04-15
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta Crystallogr.,Sect.D, 64, 2008
2PIY
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BU of 2piy by Molmil
CRYSTAL STRUCTURE OF ACTIVATED PORCINE PANCREATIC CARBOXYPEPTIDASE B (S)-2-(3-Aminomethyl-phenyl)-3-{hydroxy-[(R)-2-methyl-1-(3-phenyl-propane-1-sulfonylamino)-propyl]-phosphinoyl}-propionic acid {ZK 528} COMPLEX
分子名称: (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID, Carboxypeptidase B, ZINC ION
著者Adler, M, Whitlow, M.
登録日2007-04-15
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of potent selective peptide mimetics bound to carboxypeptidase B.
Acta Crystallogr.,Sect.D, 64, 2008
2PCU
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Human carboxypeptidase A4 in complex with a cleaved hexapeptide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC ACID, Carboxypeptidase A4, ...
著者Bayes, A, Fernandez, D, Sola, M, Marrero, A, Garcia-Pique, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X.
登録日2007-03-30
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Biochemistry, 46, 2007
2NSM
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BU of 2nsm by Molmil
Crystal structure of the human carboxypeptidase N (Kininase I) catalytic domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase N catalytic chain, SULFATE ION
著者Keil, C, Maskos, K, Than, M, Hoopes, J.T, Huber, R, Tan, F, Deddish, P.A, Erdoes, E.G, Skidgel, R.A, Bode, W.
登録日2006-11-05
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
J.Mol.Biol., 366, 2007
2JEW
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BU of 2jew by Molmil
Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB
分子名称: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION
著者Brown, D.G, Moore, R.S.
登録日2007-01-24
公開日2007-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.
J. Med. Chem., 50, 2007
2CTC
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BU of 2ctc by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2CTB
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Teplyakov, A, Wilson, K.S, Orioli, P, Mangani, S.
登録日1993-04-02
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-resolution structure of the complex between carboxypeptidase A and L-phenyl lactate.
Acta Crystallogr.,Sect.D, 49, 1993
2C1C
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BU of 2c1c by Molmil
Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors
分子名称: CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION
著者Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J.
登録日2005-09-12
公開日2005-10-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors.
Proc.Natl.Acad.Sci.USA, 102, 2005
2BOA
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BU of 2boa by Molmil
Human procarboxypeptidase A4.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE A4, ...
著者Garcia-Castellanos, R, Bonet-Figueredo, R, Pallares, I, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X.
登録日2005-04-08
公開日2005-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin.
Cell.Mol.Life Sci., 62, 2005
2BO9
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Human carboxypeptidase A4 in complex with human latexin.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETONE, ...
著者Pallares, I, Bonet, R, Garcia-Castellanos, R, Ventura, S, Aviles, F.X, Vendrell, J, Gomis-Rueth, F.X.
登録日2005-04-08
公開日2005-04-15
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
2ABZ
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BU of 2abz by Molmil
Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
分子名称: Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
著者Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S.
登録日2005-07-18
公開日2006-01-31
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
1ZLI
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BU of 1zli by Molmil
Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B
分子名称: Carboxypeptidase B, ZINC ION, carboxypeptidase inhibitor
著者Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
登録日2005-05-06
公開日2005-07-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZLH
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Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
分子名称: Carboxypeptidase A1, ZINC ION, carboxypeptidase inhibitor
著者Arolas, J.L, Popowicz, G.M, Lorenzo, J, Sommerhoff, C.P, Huber, R, Aviles, F.X, Holak, T.A.
登録日2005-05-06
公開日2005-07-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Three-Dimensional Structures of Tick Carboxypeptidase Inhibitor in Complex with A/B Carboxypeptidases Reveal a Novel Double-headed Binding Mode
J.Mol.Biol., 350, 2005
1ZG9
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BU of 1zg9 by Molmil
Crystal Structure of 5-{[amino(imino)methyl]amino}-2-(sulfanylmethyl)pentanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
分子名称: 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID, ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-04-20
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG8
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Crystal Structure of (R)-2-(3-{[amino(imino)methyl]amino}phenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
分子名称: (2R)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-04-20
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG7
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Crystal Structure of 2-(5-{[amino(imino)methyl]amino}-2-chlorophenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
分子名称: 2-(5-{[AMINO(IMINO)METHYL]AMINO}-2-CHLOROPHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-04-20
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1Z5R
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Crystal Structure of Activated Porcine Pancreatic Carboxypeptidase B
分子名称: ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-03-18
公開日2005-07-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1YME
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BU of 1yme by Molmil
STRUCTURE OF CARBOXYPEPTIDASE
分子名称: CARBOXYPEPTIDASE A ALPHA, ZINC ION
著者Greenblatt, H.M, Tucker, P.A, Shoham, G.
登録日1996-07-15
公開日1997-02-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Carboxypeptidase A: native, zinc-removed and mercury-replaced forms.
Acta Crystallogr.,Sect.D, 54, 1998
1UWY
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Crystal structure of human carboxypeptidase M
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE M, ZINC ION
著者Maskos, K, Reverter, D, Bode, W.
登録日2004-02-17
公開日2004-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Human Carboxypeptidase M, a Membrane-Bound Enzyme that Regulates Peptide Hormone Activity
J.Mol.Biol., 338, 2004
1QMU
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Duck carboxypeptidase D domain II
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBOXYPEPTIDASE GP180 RESIDUES 503-882, SULFATE ION, ...
著者Gomis-Rueth, F.X, Coll, M, Aviles, F.X, Vendrell, J, Fricker, L.D.
登録日1999-10-06
公開日2000-10-13
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Avian Carboxypeptidase D Domain II : A Prototype for the Regulatory Metallocarboxypeptidase Subfamily
Embo J., 18, 1999
1PYT
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TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
分子名称: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
著者Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
登録日1995-06-21
公開日1997-01-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
1PCA
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THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION
分子名称: CITRIC ACID, PROCARBOXYPEPTIDASE A PCPA, VALINE, ...
著者Guasch, A, Coll, M, Aviles, F.X, Huber, R.
登録日1991-10-28
公開日1993-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation.
J.Mol.Biol., 224, 1992
1OBR
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CARBOXYPEPTIDASE T
分子名称: CALCIUM ION, CARBOXYPEPTIDASE T, SULFATE ION, ...
著者Teplyakov, A, Polyakov, K, Obmolova, G, Osterman, A.
登録日1996-06-22
公開日1997-01-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of carboxypeptidase T from Thermoactinomyces vulgaris.
Eur.J.Biochem., 208, 1992
1NSA
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THREE-DIMENSIONAL STRUCTURE OF PORCINE PROCARBOXYPEPTIDASE B: A STRUCTURAL BASIS OF ITS INACTIVITY
分子名称: BENZAMIDINE, PROCARBOXYPEPTIDASE B, ZINC ION
著者Huber, R.
登録日1997-07-25
公開日1997-12-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity.
EMBO J., 10, 1991
1M4L
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STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION
分子名称: CARBOXYPEPTIDASE A, ZINC ION
著者Kilshtain-Vardi, A, Glick, M, Greenblatt, H.M, Goldblum, A, Shoham, G.
登録日2002-07-03
公開日2003-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Refined structure of bovine carboxypeptidase A at 1.25 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003

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