PDB: 909 件ウェブページステータス検索Chemie searchBIRD

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5W0H	Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution 分子名称: Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2017-05-30 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56, 2017
5EN1	Crystal structure of hnRNPA2B1 in complex with RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2015-11-09 公開日 2016-11-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
5GVQ	Solution structure of the first RRM domain of human spliceosomal protein SF3b49 分子名称: Splicing factor 3B subunit 4 著者 Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2016-09-06 公開日 2017-04-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment. Protein Sci., 26, 2017
6Q2I	Solution state NMR structures of the RNA recognition motif (RRM) domain of human CstF-64 分子名称: Cleavage stimulation factor subunit 2 著者 Latham, M.P, Masoumzadeh, E. 登録日 2019-08-08 公開日 2020-08-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans. Nucleic Acids Res., 48, 2020
5D77	Structure of Mip6 RRM3 Domain 分子名称: CITRIC ACID, NITRATE ION, RNA-binding protein MIP6, ... 著者 Mohamad, N, Bravo, J. 登録日 2015-08-13 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of Mip6 RRM3 domain at 1.3 To Be Published
5DDP	L-glutamine riboswitch bound with L-glutamine 分子名称: GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DET	X-ray structure of human RBPMS in complex with the RNA 分子名称: RNA (5'-R(*UP*CP*AP*C)-3'), RNA (5'-R(P*UP*CP*AP*CP*U)-3'), RNA-binding protein with multiple splicing, ... 著者 Teplova, M, Farazi, T.A, Tuschl, T, Patel, D.J. 登録日 2015-08-25 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Q. Rev. Biophys., 49, 2016
5CYJ	X-ray structure of human RBPMS 分子名称: RNA-binding protein with multiple splicing 著者 Teplova, M, Farazi, T.A, Patel, D.J. 登録日 2015-07-30 公開日 2015-09-30 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Q. Rev. Biophys., 49, 2016
5D78	Structure of RRM3 Domain of Mip6 at 1.25 A Resolution 分子名称: BETA-MERCAPTOETHANOL, RNA-binding protein MIP6, SULFATE ION 著者 Mohamad, N, Bravo, J. 登録日 2015-08-13 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.251 Å) 主引用文献 Structure of RRM3 Domain of Mip6 at 1.25 A Resolution To Be Published
5DDQ	L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ 分子名称: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DDR	L-glutamine riboswitch bound with L-glutamine soaked with Cs+ 分子名称: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5EV1	Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal 分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.037 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV2	Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV3	Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3'), Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5EV4	Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal 分子名称: DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2015-11-19 公開日 2016-02-24 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
5DDO	Structural and Dynamic Basis for Low Affinity-High Selectivity Binding of L-glutamine by the Gln-riboswitch 分子名称: L-glutamine riboswitch (58-MER), U1 small nuclear ribonucleoprotein A 著者 Ren, A, Patel, D. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5BJR	Crystal structure of the N-terminal RRM domain from MEC-8 分子名称: AMMONIUM ION, Mec-8 protein 著者 Soufari, H, Mackereth, C.D. 登録日 2016-10-22 公開日 2017-01-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family. RNA, 23, 2017
5HO4	Crystal structure of hnRNPA2B1 in complex with 10-mer RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3') 著者 Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B. 登録日 2016-01-19 公開日 2017-02-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
2YWK	Crystal structure of RRM-domain derived from human putative RNA-binding protein 11 分子名称: Putative RNA-binding protein 11 著者 Kawazoe, M, Takemoto, C, Kaminishi, T, Uchikubo-Kamo, T, Nishino, A, Morita, S, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-20 公開日 2008-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of RRM-domain derived from human putative RNA-binding protein 11 To be Published
7ZIR	Cryo-EM structure of hnRNPDL amyloid fibrils 分子名称: Heterogeneous nuclear ribonucleoprotein D-like 著者 Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. 登録日 2022-04-08 公開日 2022-12-28 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14, 2023
2YTC	Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22 分子名称: Pre-mRNA-splicing factor RBM22 著者 Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-05 公開日 2007-10-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of RNA binding domain in Pre-mRNA-splicing factor RBM22 To be Published
7ZUG	Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain 分子名称: CHLORIDE ION, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, ... 著者 Winter, N, Kumar, M, Isupov, M.N, Wiener, R. 登録日 2022-05-12 公開日 2023-05-24 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.075 Å) 主引用文献 Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain To Be Published
4Y00	Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA 分子名称: DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 著者 Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. 登録日 2015-02-05 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
4Y0F	Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA 分子名称: DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43 著者 Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S. 登録日 2015-02-06 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.648 Å) 主引用文献 Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
6CMN	Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7 分子名称: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element 著者 Belashov, I.A, Wedekind, J.E. 登録日 2018-03-05 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Res., 46, 2018

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