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6SQQ
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BU of 6sqq by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant in complex with RNA obtained by soaking
分子名称: MAGNESIUM ION, RNA hairpin, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SQV
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BU of 6sqv by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/R70W
分子名称: SULFATE ION, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
3IRW
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BU of 3irw by Molmil
Structure of a c-di-GMP riboswitch from V. cholerae
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ...
著者Smith, K.D.
登録日2009-08-24
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of ligand binding by a c-di-GMP riboswitch.
Nat.Struct.Mol.Biol., 16, 2009
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
分子名称: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
著者Campagne, S, Allain, F.H.
登録日2019-08-26
公開日2020-10-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
6SQT
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BU of 6sqt by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant
分子名称: U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
4CH0
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BU of 4ch0 by Molmil
RRM domain from C. elegans SUP-12
分子名称: PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-27
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
5IM0
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BU of 5im0 by Molmil
Crystal structure of the RNA recognition motif of mRNA decay regulator AUF1
分子名称: Heterogeneous nuclear ribonucleoprotein D0
著者Choi, Y.J, Chang, J.H.
登録日2016-03-05
公開日2016-08-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1.
Biomed Res Int, 2016, 2016
3IIN
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BU of 3iin by Molmil
Plasticity of the kink turn structural motif
分子名称: DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*GP*AP*CP*C)-D(P*AP*GP*A)-R(P*CP*GP*GP*CP*C)-3'), DNA/RNA (5'-R(*CP*A)-D(P*T)-3'), Group I intron, ...
著者Lipchock, S.V, Strobel, S.A, Antonioli, A.H, Cochrane, J.C.
登録日2009-08-02
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.18 Å)
主引用文献Plasticity of the RNA kink turn structural motif.
Rna, 16, 2010
6SQN
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BU of 6sqn by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA
分子名称: RNA hairpin, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SXW
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BU of 6sxw by Molmil
Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
分子名称: SULFATE ION, Zinc finger protein 638
著者Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-09-26
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
To Be Published
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
分子名称: Splicing factor U2AF 65 kDa subunit
著者Kang, H.-S, Sattler, M.
登録日2019-12-17
公開日2020-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
4CIO
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BU of 4cio by Molmil
RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA
分子名称: 5'-R(*GP*GP*UP*GP*UP*GP*CP)-3', PROTEIN SUP-12, ISOFORM A
著者Amrane, S, Mackereth, C.D.
登録日2013-12-12
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4CH1
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BU of 4ch1 by Molmil
RRM domain from C. elegans SUP-12 bound to GGTGTGC DNA
分子名称: GGTGTGC, PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-28
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
5HO4
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BU of 5ho4 by Molmil
Crystal structure of hnRNPA2B1 in complex with 10-mer RNA
分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3')
著者Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B.
登録日2016-01-19
公開日2017-02-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5IQQ
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BU of 5iqq by Molmil
Crystal structure of the human RBM7 RRM domain
分子名称: RNA-binding protein 7
著者Sofos, N, Winkler, M.B.L, Brodersen, D.E.
登録日2016-03-11
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
3K0J
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BU of 3k0j by Molmil
Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module
分子名称: MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ...
著者Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R.
登録日2009-09-24
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Rna, 16, 2010
5ITH
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BU of 5ith by Molmil
TIA-1 RRM2 recognition of target oligonucleotide
分子名称: DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3'), Nucleolysin TIA-1 isoform p40
著者Waris, S, Wilce, J.A, Wilce, M.C.
登録日2016-03-16
公開日2017-02-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献TIA-1 RRM23 binding and recognition of target oligonucleotides.
Nucleic Acids Res., 45, 2017
3IWN
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BU of 3iwn by Molmil
Co-crystal structure of a bacterial c-di-GMP riboswitch
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A
著者Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R.
登録日2009-09-02
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch.
Nat.Struct.Mol.Biol., 16, 2009
4ED5
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BU of 4ed5 by Molmil
Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA
分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ...
著者Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X.
登録日2012-03-27
公開日2012-05-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
4EGL
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BU of 4egl by Molmil
Crystal structure of two tandem RNA recognition motifs of Human antigen R
分子名称: ELAV-like protein 1, GLYCEROL, SULFATE ION
著者Wang, H, Zeng, F, Liu, H, Teng, M, Li, X.
登録日2012-03-31
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of two tandem RNA recognition motifs of Human antigen R
To be Published
7ZIR
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BU of 7zir by Molmil
Cryo-EM structure of hnRNPDL amyloid fibrils
分子名称: Heterogeneous nuclear ribonucleoprotein D-like
著者Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S.
登録日2022-04-08
公開日2022-12-28
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3.
Nat Commun, 14, 2023
7ZUG
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BU of 7zug by Molmil
Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
分子名称: CHLORIDE ION, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, ...
著者Winter, N, Kumar, M, Isupov, M.N, Wiener, R.
登録日2022-05-12
公開日2023-05-24
実験手法X-RAY DIFFRACTION (1.075 Å)
主引用文献Heterogeneous nuclear ribonucleoprotein H1, qRRM2 domain
To Be Published
6CMN
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BU of 6cmn by Molmil
Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7
分子名称: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element
著者Belashov, I.A, Wedekind, J.E.
登録日2018-03-05
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription.
Nucleic Acids Res., 46, 2018
6C8U
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BU of 6c8u by Molmil
Solution structure of Musashi2 RRM1
分子名称: RNA-binding protein Musashi homolog 2
著者Xing, M, Lan, L, Douglas, J.T, Gao, P, Hanzlik, R.P, Xu, L.
登録日2018-01-25
公開日2019-01-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 2019
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
著者Kachariya, N, Sattler, M, Keil, P, Strasser, K.
登録日2022-10-04
公開日2022-11-09
最終更新日2023-02-08
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023

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