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1P0X
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F393Y mutant heme domain of flavocytochrome P450 BM3
分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
著者Ost, T.W.B, Clark, J, Miles, C.S, Walkinshaw, M.D, Reid, G.A, Chapman, S.K, Daff, S, Mowat, C.G.
登録日2003-04-11
公開日2003-12-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oxygen Activation and Electron Transfer in Flavocytochrome P450 BM3
J.Am.Chem.Soc., 125, 2003
1P0W
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F393W mutant heme domain of flavocytochrome P450 BM3
分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
著者Ost, T.W.B, Clark, J, Miles, C.S, Walkinshaw, M.D, Reid, G.A, Chapman, S.K, Daff, S, Mowat, C.G.
登録日2003-04-11
公開日2003-12-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oxygen Activation and Electron Transfer in Flavocytochrome P450 BM3
J.Am.Chem.Soc., 125, 2003
1ODO
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1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2)
分子名称: 4-PHENYL-1H-IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 154A1
著者Podust, L.M, Kim, Y, Arase, M, Bach, H, Sherman, D.H, Lamb, D.C, Kelly, S.L, Waterman, M.R.
登録日2003-02-19
公開日2004-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Comparison of the 1.85 A Structure of Cyp154A1 from Streptomyces Coelicolor A3(2) with the Closely Related Cyp154C1 and Cyps from Antibiotic Biosynthetic Pathways.
Protein Sci., 13, 2004
1PQ2
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Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
分子名称: Cytochrome P450 2C8, PALMITIC ACID, PHOSPHATE ION, ...
著者Schoch, G.A, Yano, J.K, Wester, M.R, Griffin, K.J, Stout, C.D, Johnson, E.F.
登録日2003-06-17
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site
J.Biol.Chem., 279, 2004
1T86
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Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A)
分子名称: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ...
著者Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L.
登録日2004-05-11
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
1T87
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Crystal Structure of the Ferrous CO-bound Cytochrome P450cam (C334A)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CARBON MONOXIDE, ...
著者Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L.
登録日2004-05-11
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
1T88
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Crystal Structure of the Ferrous Cytochrome P450cam (C334A)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ...
著者Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L.
登録日2004-05-11
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
1T85
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Crystal Structure of the Ferrous CO-bound Cytochrome P450cam Mutant (L358P/C334A)
分子名称: CAMPHOR, CARBON MONOXIDE, Cytochrome P450-cam, ...
著者Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L.
登録日2004-05-11
公開日2004-06-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding.
J.Biol.Chem., 279, 2004
1SMI
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A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme
分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
著者Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D.
登録日2004-03-09
公開日2004-06-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme
J.Biol.Chem., 279, 2004
1SMJ
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Structure of the A264E mutant of cytochrome P450 BM3 complexed with palmitoleate
分子名称: Bifunctional P-450:NADPH-P450 reductase, PALMITOLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE
著者Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D.
登録日2004-03-09
公開日2004-06-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme
J.Biol.Chem., 279, 2004
1R9O
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Crystal Structure of P4502C9 with Flurbiprofen bound
分子名称: Cytochrome P450 2C9, FLURBIPROFEN, GLYCEROL, ...
著者Wester, M.R, Yano, J.K, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F.
登録日2003-10-30
公開日2004-06-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution
J.Biol.Chem., 279, 2004
1UE8
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Crystal Structure of Thermophilic Cytochrome P450 from Sulfolobus tokodaii
分子名称: 367aa long hypothetical cytochrome P450, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE
著者Nakamura, N, Kamitori, S, Ohno, H.
登録日2003-05-09
公開日2004-07-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and direct electrochemistry of cytochrome P450 from the thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain 7
J.Inorg.Biochem., 98, 2004
1SUO
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Structure of mammalian cytochrome P450 2B4 with bound 4-(4-chlorophenyl)imidazole
分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE
著者Scott, E.E, White, M.A, He, Y.A, Johnson, E.F, Stout, C.D, Halpert, J.R.
登録日2004-03-26
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9 {angstrom} resolution: Insight into the range of P450 conformations and coordination of redox partner binding.
J.Biol.Chem., 279, 2004
1W0G
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Crystal structure of human cytochrome P450 3A4
分子名称: CYTOCHROME P450 3A4, METYRAPONE, PROTOPORPHYRIN IX CONTAINING FE
著者Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H.
登録日2004-06-03
公開日2004-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
Science, 305, 2004
1W0F
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Crystal structure of human cytochrome P450 3A4
分子名称: CYTOCHROME P450 3A4, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
著者Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H.
登録日2004-06-03
公開日2004-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
Science, 305, 2004
1W0E
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Crystal structure of human cytochrome P450 3A4
分子名称: CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE
著者Williams, P.A, Cosme, J, Vinkovic, D.M, Ward, A, Angove, H.C, Day, P.J, Vonrhein, C, Tickle, I.J, Jhoti, H.
登録日2004-06-03
公開日2004-07-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone
Science, 305, 2004
1TQN
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BU of 1tqn by Molmil
Crystal Structure of Human Microsomal P450 3A4
分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 3A4
著者Yano, J.K, Wester, M.R, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F.
登録日2004-06-17
公開日2004-07-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution
J.Biol.Chem., 279, 2004
1U13
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Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis
分子名称: Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE
著者Podust, L.M, Yermalitskaya, L.V, Kim, Y, Waterman, M.R.
登録日2004-07-14
公開日2004-07-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis
To be published
1ULW
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Crystal structure of P450nor Ser73Gly/Ser75Gly mutant
分子名称: Cytochrome P450 55A1, PROTOPORPHYRIN IX CONTAINING FE
著者Oshima, R, Fushinobu, S, Su, F, Li, Z, Takaya, N, Shoun, H.
登録日2003-09-16
公開日2004-10-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for direct hydride transfer from NADH to cytochrome P450nor
J.Mol.Biol., 342, 2004
1XQD
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Crystal structure of P450NOR complexed with 3-pyridinealdehyde adenine dinucleotide
分子名称: CYTOCHROME P450 55A1, NICOTINIC ACID ADENINE DINUCLEOTIDE, PROTOPORPHYRIN IX CONTAINING FE
著者Oshima, R, Fushinobu, S, Takaya, N, Su, F, Wakagi, T, Shoun, H.
登録日2004-10-12
公開日2004-10-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural evidence for direct hydride transfer from NADH to cytochrome P450nor
J.Mol.Biol., 342, 2004
1RF9
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Crystal structure of cytochrome P450-cam with a fluorescent probe D-4-AD (Adamantane-1-carboxylic acid-5-dimethylamino-naphthalene-1-sulfonylamino-butyl-amide)
分子名称: 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-BUTYL-AMIDE, Cytochrome P450-cam, ...
著者Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B.
登録日2003-11-07
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational States of Cytochrome P450cam Revealed by Trapping of synthetic Molecular Wires
J.Mol.Biol., 344, 2004
1RE9
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CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM WITH A FLUORESCENT PROBE D-8-AD (ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE)
分子名称: 1,2-ETHANEDIOL, ADAMANTANE-1-CARBOXYLIC ACID-5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONYLAMINO-OCTYL-AMIDE, Cytochrome P450-cam, ...
著者Hays, A.-M.A, Dunn, A.R, Gray, H.B, Stout, C.D, Goodin, D.B.
登録日2003-11-06
公開日2004-11-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires.
J.Mol.Biol., 344, 2004
1X8V
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Estriol-bound and ligand-free structures of sterol 14alpha-demethylase (CYP51)
分子名称: Cytochrome P450 51, ESTRIOL, PROTOPORPHYRIN IX CONTAINING FE
著者Podust, L.M, Yermalitskaya, L.V, Lepesheva, G.I, Podust, V.N, Dalmasso, E.A, Waterman, M.R.
登録日2004-08-18
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Estriol Bound and Ligand-free Structures of Sterol 14alpha-Demethylase.
Structure, 12, 2004
1WIY
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Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Kousumi, Y, Nakagawa, N, Kaneko, M, Yamamoto, H, Masui, R, Kuramitsu, S, Ueyama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure Analysis of Cytochrome P450 from Thermus thermophilus HB8
To be Published
1S1F
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Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways
分子名称: 4-PHENYL-1H-IMIDAZOLE, GLYCEROL, MALONIC ACID, ...
著者Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R.
登録日2004-01-06
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2
J.Biol.Chem., 280, 2005

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