2H6B
 
 | |
3FX3
 | | Structure of a putative cAMP-binding regulatory protein from Silicibacter pomeroyi DSS-3 | | 分子名称: | Cyclic nucleotide-binding protein, GLYCEROL, PHOSPHATE ION | | 著者 | Cuff, M.E, Zhou, M, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-01-19 | | 公開日 | 2009-03-24 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a putative cAMP-binding regulatory protein from Silicibacter pomeroyi DSS-3
TO BE PUBLISHED
|
|
4QXK
 | | Joint X-ray/neutron structure of PKGIbeta in complex with cGMP | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-dependent protein kinase 1 | | 著者 | Kim, C, Gerlits, O, Kovalevsky, A, Huang, G.Y. | | 登録日 | 2014-07-21 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | NEUTRON DIFFRACTION (2.2 Å), X-RAY DIFFRACTION | | 主引用文献 | Neutron Diffraction Reveals Hydrogen Bonds Critical for cGMP-Selective Activation: Insights for cGMP-Dependent Protein Kinase Agonist Design.
Biochemistry, 53, 2014
|
|
4N9H
 | | Crystal structure of Transcription regulation Protein CRP | | 分子名称: | Catabolite gene activator | | 著者 | Lee, B.J, Seok, S.H, Im, H, Yoon, H.J. | | 登録日 | 2013-10-21 | | 公開日 | 2014-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structures of inactive CRP species reveal the atomic details of the allosteric transition that discriminates cyclic nucleotide second messengers.
Acta Crystallogr.,Sect.D, 70, 2014
|
|
2QCS
 | | A complex structure between the Catalytic and Regulatory subunit of Protein Kinase A that represents the inhibited state | | 分子名称: | ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Kim, C, Cheng, C.Y, Saldanha, A.S, Taylor, S.S. | | 登録日 | 2007-06-19 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Cell(Cambridge,Mass.), 130, 2007
|
|
2GZW
 | | Crystal structure of the E.coli CRP-cAMP complex | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | | 著者 | Kumarevel, T.S, Tanaka, T, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-05-12 | | 公開日 | 2007-05-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structure of activated CRP protein from E coli
To be Published
|
|
3OF1
 | | Crystal Structure of Bcy1, the Yeast Regulatory Subunit of PKA | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase regulatory subunit | | 著者 | Rinaldi, J, Wu, J, Yang, J, Ralston, C.Y, Sankaran, B, Moreno, S, Taylor, S.S. | | 登録日 | 2010-08-13 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling.
Structure, 18, 2010
|
|
7ETS
 | | Crystal structure of crp protein from Gardnerella Vaginalis | | 分子名称: | Crp/Fnr family transcriptional regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Dong, H.J, Wang, S, Zhang, J.M, Gu, L. | | 登録日 | 2021-05-13 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Crystal structure of crp protein from Gardnerella Vaginalis
To Be Published
|
|
7T4W
 | | Crystal Structure of cGMP-dependent Protein Kinase | | 分子名称: | (2R)-2-({(2S,3S)-1-[(1H-benzimidazol-2-yl)methyl]-2-phenylpiperidin-3-yl}oxy)-2-(3,5-dichlorophenyl)ethan-1-ol, CHLORIDE ION, cGMP-dependent protein kinase 1 | | 著者 | Zebisch, M, Silvestre, L, Fischmann, T.O. | | 登録日 | 2021-12-10 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
|
|
5KHG
 | | HCN2 CNBD in complex with cytidine-3', 5'-cyclic monophosphate (cCMP) | | 分子名称: | 4-amino-1-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]pyrimidin-2(1H)-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A. | | 登録日 | 2016-06-14 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.241 Å) | | 主引用文献 | Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
|
|
6M63
 | | Crystal structure of a cAMP sensor G-Flamp1. | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Chimera of Cyclic nucleotide-gated potassium channel mll3241 and Yellow fluorescent protein | | 著者 | Zhou, Z, Chen, S, Wang, L, Chu, J. | | 登録日 | 2020-03-12 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | A high-performance genetically encoded fluorescent indicator for in vivo cAMP imaging.
Nat Commun, 13, 2022
|
|
4ONU
 | |
2XKO
 | |
2Q0A
 | | Structure and rearrangements in the carboxy-terminal region of SpIH channels | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Flynn, G.E, Black, K.D, Islas, L.D, Sankaran, B, Zagotta, W.N. | | 登録日 | 2007-05-21 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure and rearrangements in the carboxy-terminal region of SpIH channels.
Structure, 15, 2007
|
|
7T4V
 | | Crystal Structure of cGMP-dependent Protein Kinase | | 分子名称: | 4-({(2S,3S)-3-[(1S)-1-(3,5-dichlorophenyl)-2-hydroxyethoxy]-2-phenylpiperidin-1-yl}methyl)-3-methylbenzoic acid, CHLORIDE ION, cGMP-dependent protein kinase 1 | | 著者 | Zebisch, M, Silvestre, L, Fischmann, T.O. | | 登録日 | 2021-12-10 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Selective small molecule activation of PKG1alpha: structure and function
Commun Biol, 2023
|
|
3I59
 | | Crystal structure of MtbCRP in complex with N6-cAMP | | 分子名称: | (2R)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, (2S)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, CHLORIDE ION, ... | | 著者 | Reddy, M.C, Palaninathan, S.K, Bruning, J.B, Thurman, C, Smith, D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2009-07-03 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.
J.Biol.Chem., 284, 2009
|
|
3U10
 | | Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | | 登録日 | 2011-09-29 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
|
|
3PLQ
 | | Crystal structure of PKA type I regulatory subunit bound with Rp-8-Br-cAMPS | | 分子名称: | (2R,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-sulfide, ZINC ION, cAMP-dependent protein kinase type I-alpha regulatory subunit | | 著者 | Swaminathan, K. | | 登録日 | 2010-11-15 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: Conformational selection highlights a new concept in allosteric inhibitor design
To be Published
|
|
3UKT
 | |
2HKX
 | | Structure of CooA mutant (N127L/S128L) from Carboxydothermus hydrogenoformans | | 分子名称: | CARBON MONOXIDE, Carbon monoxide oxidation system transcription regulator CooA-1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lanz, N.D, Borjigin, M, Li, H, Kerby, R.L, Poulos, T.L, Roberts, G.P. | | 登録日 | 2006-07-05 | | 公開日 | 2007-03-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-based hypothesis on the activation of the CO-sensing transcription factor CooA.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
1Q5O
 | | HCN2J 443-645 in the presence of cAMP, selenomethionine derivative | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | | 著者 | Zagotta, W.N, Olivier, N.B, Black, K.D, Young, E.C, Olson, R, Gouaux, J.E. | | 登録日 | 2003-08-08 | | 公開日 | 2003-09-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | STRUCTURAL BASIS FOR MODULATION AND AGONIST SPECIFICITY OF HCN PACEMAKER CHANNELS
Nature, 425, 2003
|
|
1O5L
 | |
1NE6
 | | Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase | | 分子名称: | 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain | | 著者 | Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S. | | 登録日 | 2002-12-10 | | 公開日 | 2004-01-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
|
|
5DZC
 | | Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - AMPPNP bound | | 分子名称: | CHLORIDE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION, ... | | 著者 | Walker, J.R, El Bakkouri, M, Loppnau, P, Graslund, S, He, H, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | | 登録日 | 2015-09-25 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
2XHK
 | |
