5DZC

Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium Vivax - AMPPNP bound

Summary for 5DZC

Entry DOI	10.2210/pdb5dzc/pdb
Related	4MYI 4WJC
Descriptor	cGMP-dependent protein kinase, putative, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, UNKNOWN ATOM OR ION, ... (6 entities in total)
Functional Keywords	structural genomics consortium (sgc), kinase, transferase
Biological source	Plasmodium vivax (strain Salvador I)
Total number of polymer chains	1
Total formula weight	97362.19
Authors	Walker, J.R.,El Bakkouri, M.,Loppnau, P.,Graslund, S.,He, H.,Seitova, A.,Hutchinson, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Hui, R.,Amani, M.,Structural Genomics Consortium (SGC) (deposition date: 2015-09-25, release date: 2015-10-14, Last modification date: 2023-09-27)
Primary citation	El Bakkouri, M.,Kouidmi, I.,Wernimont, A.K.,Amani, M.,Hutchinson, A.,Loppnau, P.,Kim, J.J.,Flueck, C.,Walker, J.R.,Seitova, A.,Senisterra, G.,Kakihara, Y.,Kim, C.,Blackman, M.J.,Calmettes, C.,Baker, D.A.,Hui, R. Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation. Proc.Natl.Acad.Sci.USA, 116:14164-14173, 2019 Cited by PubMed: 31239348 DOI: 10.1073/pnas.1905558116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation