PDB: 594 件ウェブページステータス検索Chemie searchBIRD

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1NZL	Crystal Structure of Src SH2 domain bound to doubly phosphorylated peptide PQpYEpYIPI 分子名称: CHLORIDE ION, Doubly phosphorylated peptide ligand (PQpYEpYIPI), TETRAETHYLENE GLYCOL, ... 著者 Lubman, O.Y, Waksman, G. 登録日 2003-02-18 公開日 2003-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Thermodynamic Basis for the Interaction of the Src SH2 domain with the Activated form of the PDGF beta-receptor J.Mol.Biol., 328, 2003
1NZV	Crystal Structure of Src SH2 domain bound to doubly phosphorylated peptide PQpYIpYVPA 分子名称: CHLORIDE ION, Doubly phosphorylated peptide PQpYIpYVPA, TETRAETHYLENE GLYCOL, ... 著者 Lubman, O.Y, Waksman, G. 登録日 2003-02-19 公開日 2003-04-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Thermodynamic Basis for the Interaction of the Src SH2 domain with the Activated form of the PDGF beta-receptor J.Mol.Biol., 328, 2003
1M27	Crystal structure of SAP/FynSH3/SLAM ternary complex 分子名称: CITRATE ANION, Proto-oncogene tyrosine-protein kinase FYN, SH2 domain protein 1A, ... 著者 Chan, B, Griesbach, J, Song, H.K, Poy, F, Terhorst, C, Eck, M.J. 登録日 2002-06-21 公開日 2003-05-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 SAP couples Fyn to SLAM immune receptors. NAT.CELL BIOL., 5, 2003
1M61	Crystal structure of the apo SH2 domains of ZAP-70 分子名称: PHOSPHATE ION, TYROSINE-PROTEIN KINASE ZAP-70 著者 Folmer, R.H.A, Geschwindner, S, Xue, Y. 登録日 2002-07-11 公開日 2003-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem Biochemistry, 41, 2002
1P13	Crystal Structure of the Src SH2 Domain Complexed with Peptide (SDpYANFK) 分子名称: CACODYLATE ION, Peptide, Proto-oncogene tyrosine-protein kinase Src 著者 Sonnenburg, E.D, Bilwes, A, Hunter, T, Noel, J.P. 登録日 2003-04-11 公開日 2003-08-19 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region. Biochemistry, 42, 2003
1MW4	Solution structure of the human Grb7-SH2 domain in complex with a 10 amino acid peptide pY1139 分子名称: Growth factor receptor-bound protein 7, Receptor protein-tyrosine kinase erbB-2 著者 Ivancic, M, Lyons, B.A. 登録日 2002-09-27 公開日 2003-09-09 最終更新日 2012-05-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2 J.BIOMOL.NMR, 27, 2003
1RPY	CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS 分子名称: SULFATE ION, adaptor protein APS 著者 Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R. 登録日 2003-12-03 公開日 2003-12-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell, 12, 2003
1RQQ	Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS 分子名称: BISUBSTRATE INHIBITOR, Insulin receptor, MANGANESE (II) ION, ... 著者 Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R. 登録日 2003-12-06 公開日 2003-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell, 12, 2003
1O4P	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78791. 分子名称: 2-PHENYLMALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4J	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH ISO24. 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, [(4-ETHYLPHENYL)AMINO]CARBONYLPHOSPHONIC ACID 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O43	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82129. 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, [4-((1Z)-2-(ACETYLAMINO)-3-{[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]AMINO}-3-OXOPROP-1-ENYL)-2-FORMYLPHENYL]ACET IC ACID 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O49	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU85493. 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, {4-[2-ACETYLAMINO-2-(1-BIPHENYL-4-YLMETHYL-2-OXO-AZEPAN-3-YLCARBAMOYL)-ETHYL]-2-PHOSPHONO-PHENOXY}-ACETIC ACID 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4G	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH DPI59. 分子名称: HYDROXY(1-NAPHTHYL)METHYLPHOSPHONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4M	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH MALONICACID. 分子名称: MALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O45	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU84687. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-3-FORMYL-O-PHOSPHONOTYROSINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4F	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79073. 分子名称: 1,2,3,4-TETRAHYDROQUINOLIN-8-YL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4K	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH PASBN. 分子名称: BENZYL 2-FORMYLPHENYL HYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O46	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU90395. 分子名称: 2-{4-[2-ACETYLAMINO-2-(1-BIPHENYL-4-YLMETHYL-2-OXO-AZEPAN-3-YLCARBAMOYL)-ETHYL]-2-METHOXYCARBONYL-PHENYL}-2-FLUORO-MALONIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O41	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78300. 分子名称: 2-FORMYL-6-METHOXYPHENYL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O47	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82209. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-4-[DIFLUORO(PHOSPHONO)METHYL]PHENYLALANINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4H	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79072. 分子名称: 2-CYANOQUINOLIN-8-YL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4L	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH FRAGMENT2. 分子名称: CITRIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4A	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82197. 分子名称: 4-[2-ACETYLAMINO-2-(1-BIPHENYL-4-YLMETHYL-2-OXO-AZEPAN-3-YLCARBAMOYL)-ETHYL]-2-FORMYL-BENZOIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O4B	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU83876. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-3,4-DIPHOSPHONOPHENYLALANINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003
1O42	CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU81843. 分子名称: N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-O-PHOSPHONOTYROSINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC 著者 Lange, G, Loenze, P, Liesum, A. 登録日 2003-06-15 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J.Med.Chem., 46, 2003

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