PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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7N6N	SARS-CoV-2 Main protease C145S mutant in complex with N and C-terminal residues 分子名称: 3C-like proteinase 著者 Noske, G.D, Nakamura, A.M, Gawriljuk, V.O, Lima, G.M.A, Zeri, A.C.M, Nascimento, A.F.Z, Fernandes, R.S, Oliva, G, Godoy, A.S. 登録日 2021-06-08 公開日 2021-06-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process. J.Mol.Biol., 433, 2021
8ORL	Crystal structure of the S23226G missense variant of titin domain Fn3-56 分子名称: CHLORIDE ION, Titin, ZINC ION 著者 Rees, M, Gautel, M. 登録日 2023-04-14 公開日 2023-08-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
6UAO	Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peptide EEYSAM, ... 著者 Toth, E.A, Bryan, P.N, Orban, J. 登録日 2019-09-11 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4, 2021
7UYQ	Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination 分子名称: Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Wu, S, Gabelli, S.B, Sohn, J. 登録日 2022-05-07 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
6L2N	Crystal structure of the R.PabI(Y68F-K154A)-dsDNA(GTAC-3bp-GTAC) complex 分子名称: DNA (5'-D(*TP*CP*AP*GP*CP*AP*GP*TP*AP*CP*TP*AP*AP*GP*TP*AP*CP*TP*GP*CP*TP*GP*A)-3'), RE_R_Pab1 domain-containing protein 著者 Miyazono, K, Wang, D, Ito, T, Tanokura, M. 登録日 2019-10-05 公開日 2020-03-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI. Nucleic Acids Res., 48, 2020
6TXD	Variant W229D/F290W-12 of the last common ancestor of Gram-negative bacteria beta-lactamase class A (GNCA4) 分子名称: ACETATE ION, Beta lactamase (GNCA4-12), FORMIC ACID, ... 著者 Gavira, J.A, Risso, V, Sanchez-Ruiz, J.M, Romero-Rivera, A, Kamerlin, S.C.L. 登録日 2020-01-14 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enhancing ade novoenzyme activity by computationally-focused ultra-low-throughput screening. Chem Sci, 11, 2020
8BBB	IPNS H270A variant in complex with ACV exposed to O2 分子名称: Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, SULFATE ION 著者 Rabe, P, Schofield, C.J. 登録日 2022-10-12 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 IPNS H270A variant in complex with ACV exposed to O2 To Be Published
8OS3	Crystal structure of the titin domain Fn3-11 分子名称: Titin 著者 Nikoopour, R, Rees, M, Gautel, M. 登録日 2023-04-17 公開日 2023-08-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
8OTY	Crystal structure of the titin domain Fn3-90 分子名称: Titin 著者 Nikoopour, R, Rees, M, Gautel, M. 登録日 2023-04-21 公開日 2023-08-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
8BBZ	Crystal Structure of SilF (apo form) 分子名称: SilF, ZINC ION 著者 Lithgo, R.M, Carr, S.B, Quigley, A.M, Scott, D.J. 登録日 2022-10-14 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of SilF (apo form) To Be Published
6A5W	FXR-LBD with HNC143 and SRC1 分子名称: 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1 著者 Wang, N, Liu, J. 登録日 2018-06-25 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding J. Biol. Chem., 293, 2018
7UYX	Structure of bacteriophage PA1c gp2 分子名称: Bacteriophage PA1C gp2 著者 Enustun, E, Deep, A, Gu, Y, Nguyen, K, Chaikeeratisak, V, Armbruster, E, Ghassemian, M, Pogliano, J, Corbett, K.D. 登録日 2022-05-07 公開日 2023-05-10 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Identification of the bacteriophage nucleus protein interaction network. Nat.Struct.Mol.Biol., 30, 2023
7N50	Structure of a bacterial gasdermin from Bradyrhizobium tropiciagri 分子名称: Gasdermin 著者 Johnson, A.G, Kranzusch, P.J. 登録日 2021-06-04 公開日 2021-06-23 最終更新日 2022-01-26 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Bacterial gasdermins reveal an ancient mechanism of cell death. Science, 375, 2022
4ZDZ	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Tyndall, J.D.A, Monk, B.C. 登録日 2015-04-20 公開日 2016-03-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
7UYZ	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG 分子名称: Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wu, S, Gabelli, S.B, Sohn, J. 登録日 2022-05-07 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
8OT5	Crystal structure of the titin domain Fn3-85 分子名称: CHLORIDE ION, SODIUM ION, Titin 著者 Nikoopour, R, Rees, M, Gautel, M. 登録日 2023-04-20 公開日 2023-08-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
7RYO	CD1a-dideoxymycobactin-gdTCR complex 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, SULFATE ION, ... 著者 Wegrecki, M, Le Nours, J, Rossjohn, J. 登録日 2021-08-25 公開日 2022-05-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Atypical sideways recognition of CD1a by autoreactive gamma delta T cell receptors. Nat Commun, 13, 2022
6L7V	Crystal structure of Cet1 from Trypanosoma cruzi in complex with tripolyphosphate, manganese and iodide ions. 分子名称: IODIDE ION, MANGANESE (II) ION, TRIPHOSPHATE, ... 著者 Kuwabara, N, Ho, K. 登録日 2019-11-03 公開日 2020-06-03 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of the RNA triphosphatase fromTrypanosoma cruziprovide insights into how it recognizes the 5'-end of the RNA substrate. J.Biol.Chem., 295, 2020
7V1A	Stapled TBS peptide from RIAM bound to talin R7R8 domains 分子名称: 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1 著者 Zhang, P, Gao, T, Wu, J. 登録日 2022-05-11 公開日 2023-06-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Inhibition of talin-induced integrin activation by a double-hit stapled peptide. Structure, 31, 2023
7NIG	14-3-3 sigma with Pin1 binding site pS72 and covalently bound LvD1008 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-imidazol-1-yl-benzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-02-12 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
7UZR	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG 分子名称: Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... 著者 Wu, S, Gabelli, S.B, Sohn, J. 登録日 2022-05-09 公開日 2023-05-10 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS Nat Commun, 15, 2024
6L8F	Crystal structure of heterotetrameric complex of YoeB-YefM toxin-antitoxin from Staphylococcus aureus. 分子名称: Antitoxin, YoeB 著者 Yue, J, Xue, L. 登録日 2019-11-06 公開日 2020-09-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Distinct oligomeric structures of the YoeB-YefM complex provide insights into the conditional cooperativity of type II toxin-antitoxin system. Nucleic Acids Res., 48, 2020
6UBR	Crystal structure of D678A GoxA bound to glycine at pH 7.5 分子名称: DI(HYDROXYETHYL)ETHER, GLYCINE, MAGNESIUM ION, ... 著者 Yukl, E.T, Avalos, D. 登録日 2019-09-12 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Kinetic and structural evidence that Asp-678 plays multiple roles in catalysis by the quinoprotein glycine oxidase. J.Biol.Chem., 294, 2019
6ON0	STRUCTURE OF N15 CRO COMPLEXED WITH CONSENSUS OPERATOR DNA 分子名称: DNA (5'-D(*TP*TP*TP*AP*TP*AP*GP*CP*TP*AP*GP*CP*TP*AP*TP*AP*A)-3'), Gp39 著者 Hall, B.M, Roberts, S.A, Cordes, M.H.J. 登録日 2019-04-19 公開日 2019-05-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Extreme divergence between one-to-one orthologs: the structure of N15 Cro bound to operator DNA and its relationship to the lambda Cro complex. Nucleic Acids Res., 47, 2019
7V0C	Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG 分子名称: Cyclic GMP-AMP synthase, MANGANESE (II) ION, Palindromic DNA18, ... 著者 Wu, S, Gabelli, S.B, Sohn, J. 登録日 2022-05-10 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG To Be Published

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