1Y98
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![BU of 1y98 by Molmil](/molmil-images/mine/1y98) | Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide. | 分子名称: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ... | 著者 | Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A. | 登録日 | 2004-12-14 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex. Biochemistry, 44, 2005
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3ZEE
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![BU of 3zee by Molmil](/molmil-images/mine/3zee) | Electron cyro-microscopy helical reconstruction of Par-3 N terminal domain | 分子名称: | PARTITIONING DEFECTIVE 3 HOMOLOG | 著者 | Zhang, Y, Wang, W, Chen, J, Zhang, K, Gao, F, Gong, W, Zhang, M, Sun, F, Feng, W. | 登録日 | 2012-12-05 | 公開日 | 2013-10-16 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural Insights Into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain. Structure, 21, 2013
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4B2D
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![BU of 4b2d by Molmil](/molmil-images/mine/4b2d) | human PKM2 with L-serine and FBP bound. | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVATE KINASE ISOZYMES M1/M2, ... | 著者 | Chaneton, B, Hillmann, P, Zheng, L, Martin, A.C.L, Maddocks, O.D.K, Chokkathukalam, A, Coyle, J.E, Jankevics, A, Holding, F.P, Vousden, K.H, Frezza, C, O'Reilly, M, Gottlieb, E. | 登録日 | 2012-07-13 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Serine is a natural ligand and allosteric activator of pyruvate kinase M2. Nature, 491, 2012
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4AVU
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![BU of 4avu by Molmil](/molmil-images/mine/4avu) | Crystal structure of human tankyrase 2 in complex with 6(5H)- phenanthridinone | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... | 著者 | Haikarainen, T, Narwal, M, Lehtio, L. | 登録日 | 2012-05-29 | 公開日 | 2012-06-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Evaluation and Structural Basis for the Inhibition of Tankyrases by Parp Inhibitors Acs Med.Chem.Lett., 5, 2014
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4B6H
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2A20
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![BU of 2a20 by Molmil](/molmil-images/mine/2a20) | Solution structure of Rim2 Zinc Finger Domain | 分子名称: | Regulating synaptic membrane exocytosis protein 2, ZINC ION | 著者 | Dulubova, I, Lou, X, Lu, J, Huryeva, I, Alam, A, Schneggenburger, R, Sudhof, T.C, Rizo, J. | 登録日 | 2005-06-21 | 公開日 | 2005-08-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? Embo J., 24, 2005
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2AK5
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![BU of 2ak5 by Molmil](/molmil-images/mine/2ak5) | beta PIX-SH3 complexed with a Cbl-b peptide | 分子名称: | 8-residue peptide from a signal transduction protein CBL-B, Rho guanine nucleotide exchange factor 7 | 著者 | Jozic, D, Cardenes, N, Deribe, Y.L, Moncalian, G, Hoeller, D, Groemping, Y, Dikic, I, Rittinger, K, Bravo, J. | 登録日 | 2005-08-03 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Cbl promotes clustering of endocytic adaptor proteins. Nat.Struct.Mol.Biol., 12, 2005
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8W6A
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8W6B
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3E93
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2R4H
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![BU of 2r4h by Molmil](/molmil-images/mine/2r4h) | Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase | 分子名称: | HISTIDINE, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | 著者 | Ugochukwu, E, Pilka, E.S, Hozjan, V, Kavanagh, K.L, Cooper, C, Pike, A.C.W, Elkins, J.M, Doyle, D.A, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-08-31 | 公開日 | 2007-10-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of a C1190S mutant of the 6th PDZ domain of human membrane associated guanylate kinase. To be Published
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4Z7L
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![BU of 4z7l by Molmil](/molmil-images/mine/4z7l) | Crystal structure of Cas6b | 分子名称: | Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION | 著者 | Li, H. | 登録日 | 2015-04-07 | 公開日 | 2016-04-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6. Structure, 24, 2016
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3E92
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![BU of 3e92 by Molmil](/molmil-images/mine/3e92) | Crystal Structure of P38 Kinase in Complex with A Biaryl Amide Inhibitor | 分子名称: | GLYCEROL, Mitogen-activated protein kinase 14, N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide | 著者 | Somers, D.O, Patel, S. | 登録日 | 2008-08-21 | 公開日 | 2008-09-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Kinase array design, back to front: Biaryl amides Bioorg.Med.Chem.Lett., 18, 2008
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7TUB
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![BU of 7tub by Molmil](/molmil-images/mine/7tub) | The beta-tubulin folding intermediate IV | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-02 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TRG
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![BU of 7trg by Molmil](/molmil-images/mine/7trg) | The beta-tubulin folding intermediate I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-01-28 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTN
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![BU of 7ttn by Molmil](/molmil-images/mine/7ttn) | The beta-tubulin folding intermediate II | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-01 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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4ZPR
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![BU of 4zpr by Molmil](/molmil-images/mine/4zpr) | Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA | 分子名称: | Aryl hydrocarbon receptor nuclear translocator, DNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... | 著者 | Wu, D, Potluri, N, Lu, J, Kim, Y, Rastinejad, F. | 登録日 | 2015-05-08 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | 主引用文献 | Structural integration in hypoxia-inducible factors. Nature, 524, 2015
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7TTT
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![BU of 7ttt by Molmil](/molmil-images/mine/7ttt) | The beta-tubulin folding intermediate III | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Zhao, Y, Frydman, J, Chiu, W. | 登録日 | 2022-02-01 | 公開日 | 2022-12-28 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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5X9Y
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5XIT
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![BU of 5xit by Molmil](/molmil-images/mine/5xit) | Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form II | 分子名称: | E3 ubiquitin-protein ligase RNF168, GLYCEROL, PRASEODYMIUM ION, ... | 著者 | Takahashi, T.S, Sato, Y, Fukai, S. | 登録日 | 2017-04-27 | 公開日 | 2018-03-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168. Nat Commun, 9, 2018
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5XHB
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8GW0
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![BU of 8gw0 by Molmil](/molmil-images/mine/8gw0) | Crystal structure of the human dihydroorotase domain in complex with malic acid | 分子名称: | (2S)-2-hydroxybutanedioic acid, CAD protein, ZINC ION | 著者 | Yang, P.C, Liu, H.W, Huang, H.Y, Huang, C.Y. | 登録日 | 2022-09-16 | 公開日 | 2023-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Complexed Crystal Structure of the Dihydroorotase Domain of Human CAD Protein with the Anticancer Drug 5-Fluorouracil. Biomolecules, 13, 2023
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4ZIF
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![BU of 4zif by Molmil](/molmil-images/mine/4zif) | Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini | 分子名称: | Apoptosis regulator BAX, Bcl-2-like protein 11 | 著者 | Robin, A.Y, Krishna Kumar, K, Westphal, D, Wardak, A.Z, Thompson, G.V, Dewson, G, Colman, P.M, Czabotar, P.E. | 登録日 | 2015-04-28 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction. Cell Death Dis, 6, 2015
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5XHZ
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2QY7
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![BU of 2qy7 by Molmil](/molmil-images/mine/2qy7) | Crystal structure of human epsinR ENTH domain | 分子名称: | Clathrin interactor 1 | 著者 | Miller, S.E, Collins, B.M, McCoy, A.J, Robinson, M.S, Owen, D.J. | 登録日 | 2007-08-13 | 公開日 | 2007-11-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Nature, 450, 2007
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