4ROE
| Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter | 分子名称: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | 著者 | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | 登録日 | 2014-10-28 | 公開日 | 2015-12-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4TRF
| |
4ROD
| Human TFIIB-related factor 2 (Brf2) and TBP bound to TRNAU1 promoter | 分子名称: | Non-template strand, TATA-box-binding protein, Template strand, ... | 著者 | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | 登録日 | 2014-10-28 | 公開日 | 2015-12-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4TRU
| |
4S3H
| Crystal structure of S. pombe Mdb1 FHA domain | 分子名称: | Mdb1, SULFATE ION | 著者 | Luo, S, Ye, K. | 登録日 | 2015-01-26 | 公開日 | 2015-07-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | Dimerization Mediated by a Divergent Forkhead-associated Domain Is Essential for the DNA Damage and Spindle Functions of Fission Yeast Mdb1. J.Biol.Chem., 290, 2015
|
|
4TWP
| The crystal structure of human abl1 T315I gatekeeper mutant kinase domain in complex with axitinib | 分子名称: | AXITINIB, NICKEL (II) ION, SODIUM ION, ... | 著者 | Johnson, E, McTigue, M, Cronin, C.N. | 登録日 | 2014-07-01 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature, 519, 2015
|
|
4TXL
| Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with uracil | 分子名称: | SULFATE ION, URACIL, Uridine phosphorylase | 著者 | Marinho, A, Torini, J, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2014-07-03 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
|
|
4RND
| |
4RSU
| Crystal structure of the light and hvem complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-11-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160. J.Exp.Med., 218, 2021
|
|
4RUM
| |
4TXM
| Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymine | 分子名称: | SULFATE ION, THYMINE, Uridine phosphorylase | 著者 | Marinho, A, Torini, J, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2014-07-03 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
|
|
4ROC
| Human TFIIB-related factor 2 (Brf2) and TBP bound to U6#2 promoter | 分子名称: | MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... | 著者 | Vannini, A, Gouge, J, Satia, K, Guthertz, N. | 登録日 | 2014-10-28 | 公開日 | 2015-12-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
|
|
4TXN
| Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with 5-fluorouracil | 分子名称: | 5-FLUOROURACIL, SULFATE ION, Uridine phosphorylase | 著者 | Marinho, A, Torini, J, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2014-07-03 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
|
|
4TUH
| Bcl-xL in complex with inhibitor (Compound 10) | 分子名称: | 1,2-ETHANEDIOL, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-{3-[4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy]propyl}-1,3-thiazole-4-carboxylic acid, ACETATE ION, ... | 著者 | Czabotar, P.E, Lessense, G, Smith, B.J, Colman, P.M. | 登録日 | 2014-06-24 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL. Acs Med.Chem.Lett., 5, 2014
|
|
4TXH
| Crystal structure of uridine phosphorylase from Schistosoma mansoni in APO form | 分子名称: | SULFATE ION, Uridine phosphorylase | 著者 | Torini, J, Romanello, L, Marinho, A, Brandao-Neto, J, Cassago, A, DeMarco, R, Pereira, H.M. | 登録日 | 2014-07-03 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.892 Å) | 主引用文献 | Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
|
|
4U8Z
| Crystal structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06447475) | 分子名称: | 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile, MANGANESE (II) ION, Serine/threonine-protein kinase 24 | 著者 | Jasti, J, Song, X, Griffor, M, Kurumbail, R.G. | 登録日 | 2014-08-05 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J.Med.Chem., 58, 2015
|
|
4TXJ
| Crystal structure of uridine phosphorylase from Schistosoma mansoni in complex with thymidine | 分子名称: | SULFATE ION, THYMIDINE, Uridine phosphorylase | 著者 | Torini, J, Marinho, A, Romanello, L, Cassago, A, DeMarco, R, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2014-07-03 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.662 Å) | 主引用文献 | Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
|
|
4U87
| Crystal structure of the Ba-soaked C2 crystal form of pMV158 replication initiator RepB (P3221 space group) | 分子名称: | BARIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Boer, D.R, Ruiz Maso, J.A, del Solar, G, Coll, M. | 登録日 | 2014-08-01 | 公開日 | 2015-08-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158. Sci Rep, 6, 2016
|
|
4U3J
| TOG2:alpha/beta-tubulin complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein STU2, ... | 著者 | Ayaz, P, Rice, L.M. | 登録日 | 2014-07-22 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | A tethered delivery mechanism explains the catalytic action of a microtubule polymerase. Elife, 3, 2014
|
|
4U3T
| |
4U8N
| Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A complexed with UDP | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
|
|
4UN1
| Sirohaem decarboxylase AhbA/B - an enzyme with structural homology to the Lrp/AsnC transcription factor family that is part of the alternative haem biosynthesis pathway. | 分子名称: | 12,18-DIDECARBOXY-SIROHEME, PUTATIVE TRANSCRIPTIONAL REGULATOR, ASNC FAMILY | 著者 | Palmer, D.J, Brown, D.G, Warren, M.J, Pickersgill, R.W. | 登録日 | 2014-05-23 | 公開日 | 2014-06-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | The Structure, Function and Properties of Sirohaem Decarboxylase - an Enzyme with Structural Homology to a Transcription Factor Family that is Part of the Alternative Haem Biosynthesis Pathway. Mol.Microbiol., 93, 2014
|
|
2WUV
| Crystallographic analysis of counter-ion effects on subtilisin enzymatic action in acetonitrile | 分子名称: | ACETONITRILE, CALCIUM ION, CESIUM ION, ... | 著者 | Cianci, M, Tomaszewki, B, Helliwell, J.R, Halling, P.J. | 登録日 | 2009-10-09 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystallographic Analysis of Counterion Effects on Subtilisin Enzymatic Action in Acetonitrile. J.Am.Chem.Soc., 132, 2010
|
|
7POG
| High-resolution structure of native toxin A from Clostridioides difficile | 分子名称: | Toxin A, ZINC ION | 著者 | Boesen, T, Joergensen, R, Aminzadeh, A, Engelbrecht Larsen, C. | 登録日 | 2021-09-08 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | High-resolution structure of native toxin A from Clostridioides difficile. Embo Rep., 23, 2022
|
|
7PRS
| |