PDB: 13488 件ウェブページステータス検索Chemie searchBIRD

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4QAL	Crystal structure of C117A mutant of human acidic fibroblast growth factor 分子名称: CITRATE ANION, Fibroblast growth factor 1 著者 Blaber, M, Xia, X. 登録日 2014-05-05 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104, 2015
4QIB	Oxidation-Mediated Inhibition of the Peptidyl-Prolyl Isomerase Pin1 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION 著者 Innes, B.T, Sowole, M.A, Konermann, L, Litchfield, D.W, Brandl, C.J, Shilton, B.H. 登録日 2014-05-30 公開日 2015-02-04 最終更新日 2015-03-04 実験手法 X-RAY DIFFRACTION (1.865 Å) 主引用文献 Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1. Biochim.Biophys.Acta, 1852, 2015
3D87	Crystal structure of Interleukin-23 分子名称: Interleukin-12 subunit p40, Interleukin-23 subunit p19, PHOSPHATE ION, ... 著者 Beyer, B.M, Ingram, R, Ramanathan, L, Reichert, P, Le, H, Madison, V. 登録日 2008-05-22 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody J.Mol.Biol., 382, 2008
3D85	Crystal structure of IL-23 in complex with neutralizing FAB 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, FAB of antibody 7G10, heavy chain, ... 著者 Beyer, B.M, Ingram, R, Ramanathan, L, Reichert, P, Le, H, Madison, V. 登録日 2008-05-22 公開日 2008-09-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody J.Mol.Biol., 382, 2008
7EJW	Crystal structure of FleN in complex with FleQ AAA+ doamain 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Chanchal, Banerjee, P, Raghav, S, Jain, D. 登録日 2021-04-02 公開日 2021-12-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The antiactivator FleN uses an allosteric mechanism to regulate sigma 54 -dependent expression of flagellar genes in Pseudomonas aeruginosa . Sci Adv, 7, 2021
3DHD	Crystal structure of human NAMPT complexed with nicotinamide mononucleotide and pyrophosphate 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MAGNESIUM ION, Nicotinamide phosphoribosyltransferase, ... 著者 Ho, M, Burgos, E.S, Almo, S.C, Schramm, V.L. 登録日 2008-06-17 公開日 2009-08-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT. Proc.Natl.Acad.Sci.USA, 106, 2009
4PSI	PIH1D1/phospho-Tel2 complex 分子名称: PIH1 domain-containing protein 1, Telomere length regulation protein TEL2 homolog 著者 Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. 登録日 2014-03-07 公開日 2014-04-23 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
7C9I	Human gamma-secretase in complex with small molecule L-685,458 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Yang, G, Zhou, R, Guo, X, Lei, J, Yan, C, Shi, Y. 登録日 2020-06-05 公開日 2021-01-27 最終更新日 2021-02-03 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of gamma-secretase inhibition and modulation by small molecule drugs. Cell, 184, 2021
2E32	Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase 分子名称: F-box only protein 2, S-phase kinase-associated protein 1A 著者 Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. 登録日 2006-11-20 公開日 2007-03-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.52 Å) 主引用文献 Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase Proc.Natl.Acad.Sci.Usa, 104, 2007
2E5C	Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase 著者 Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. 登録日 2006-12-20 公開日 2007-12-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
3FXO	Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Phosphate at 1 mM of Mn2+ 分子名称: MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A 著者 Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. 登録日 2009-01-21 公開日 2010-01-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the Mn2+-dependent activation of human PPM1A To be published
3FVI	Crystal Structure of Complex of Phospholipase A2 with Octyl Sulfates 分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... 著者 Pan, Y.H. 登録日 2009-01-15 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2. Biochim.Biophys.Acta, 1804, 2010
2ZQU	Crystal structure of a mutant PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION 著者 Jobichen, C, Liou, Y.C, Sivaraman, J. 登録日 2008-08-19 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural studies on PIN1 mutants To be Published
2E6Z	Solution structure of the second KOW motif of human transcription elongation factor SPT5 分子名称: Transcription elongation factor SPT5 著者 Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-01-05 公開日 2007-07-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second KOW motif of human transcription elongation factor SPT5 To be Published
2ZHJ	Crystal Structure Analysis of the Sodium-Bound Annexin A4 at 1.34 A resolution 分子名称: Annexin A4, SODIUM ION 著者 Butsushita, K, Ida, K, Fukuoka, S.-I, Arii, Y. 登録日 2008-02-06 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Analysis for the Soduim-Dependent Dissociation of Annexin A4: Crystal Structures of Soduim-Bound Annexin A4 at High Resolutions To be Published
2ZVU	Crystal structure of rat heme oxygenase-1 in complex with ferrous verdoheme 分子名称: 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, FORMIC ACID, Heme oxygenase 1 著者 Sato, H, Sugishima, M, Fukuyama, K, Noguchi, M. 登録日 2008-11-21 公開日 2009-02-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side Biochem.J., 419, 2009
2B53	Human cyclin dependent kinase 2 (CDK2) complexed with DIN-234325 分子名称: 6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE, Cell division protein kinase 2 著者 Muckelbauer, J. 登録日 2005-09-27 公開日 2005-10-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Quinazolines as Cyclin Dependent Kinase Inhibitors Bioorg.Med.Chem.Lett., 11, 2001
2B54	Human cyclin dependent kinase 2 (CKD2)complexed with DIN-232305 分子名称: 6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE, Cell division protein kinase 2 著者 Chang, C.-C. 登録日 2005-09-27 公開日 2005-10-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthesis and biological evaluation of 1-aryl-4,5-dihydro-1h-pyraxolo[3,4-d]pyrimidin-4-one inhibitors of cyclin dependent kinases J.Med.Chem., 47, 2004
2ZHI	Crystal Structure Analysis of the Sodium-Bound Annexin A4 at 1.58 A resolution 分子名称: Annexin A4, SODIUM ION, SULFATE ION 著者 Butsushita, K, Ida, K, Fukuoka, S.-I, Arii, Y. 登録日 2008-02-06 公開日 2009-02-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural Analysis for the Sodium-Dependent Dissociation of Annexin A4: Crystal Structures of Soduim-Bound Annexin A4 at High Resolutions To be Published
2ZFN	Self-acetylation mediated histone H3 lysine 56 acetylation by rtt109 分子名称: ACETYL COENZYME *A, GLYCEROL, Regulator of Ty1 transposition protein 109 著者 Yuan, Y.A. 登録日 2008-01-08 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into histone h3 lysine 56 acetylation by rtt109 Structure, 16, 2008
2B55	Human cyclin dependent kinase 2 (cdk2) complexed with indenopyraxole DIN-101312 分子名称: 2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE, Cell division protein kinase 2 著者 Muckelbauer, J. 登録日 2005-09-27 公開日 2005-10-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3 J.Med.Chem., 45, 2002
3FXM	Crystal Structure of Human Protein phosphatase 1A (PPM1A) Bound with Citrate at 10 mM of Mn2+ 分子名称: CITRATE ANION, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Hu, T, Wang, L, Wang, K, Jiang, H, Shen, X. 登録日 2009-01-21 公開日 2010-01-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the Mn2+-dependent activation of human PPM1A To be published
3BAD	Crystal structure of D70A/H93G mutant of Human acidic fibroblast growth factor 分子名称: Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2007-11-07 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008
4Q9G	Crystal structure of K12V/C16S/C117V/P134V mutant of human acidic fibroblast growth factor 分子名称: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION 著者 Blaber, M, Xia, X. 登録日 2014-05-01 公開日 2015-03-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.554 Å) 主引用文献 Mutation choice to eliminate buried free cysteines in protein therapeutics. J.Pharm.Sci., 104, 2015
3BAO	Crystal structure of L26N mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Lee, J, Blaber, M. 登録日 2007-11-08 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. J.Mol.Biol., 377, 2008

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