PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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5A0D	N-terminal thioester domain of surface protein from Clostridium perfringens, Cys138Ala mutant 分子名称: 1,2-ETHANEDIOL, SURFACE ANCHORED PROTEIN 著者 Walden, M, Edwards, J.M, Dziewulska, A.M, Kan, S.-Y, Schwarz-Linek, U, Banfield, M.J. 登録日 2015-04-17 公開日 2015-06-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 An internal thioester in a pathogen surface protein mediates covalent host binding. Elife, 4, 2015
5DDP	L-glutamine riboswitch bound with L-glutamine 分子名称: GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5CW4	Structure of CfBRCC36-CfKIAA0157 complex (Selenium Edge) 分子名称: BRCA1/BRCA2-containing complex subunit 3, GLYCEROL, Protein FAM175B, ... 著者 Zeqiraj, E. 登録日 2015-07-27 公開日 2015-09-16 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.543 Å) 主引用文献 Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
5ACB	Crystal Structure of the Human Cdk12-Cyclink Complex 分子名称: CYCLIN-DEPENDENT KINASE 12, CYCLIN-K, N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide 著者 Dixon Clarke, S.E, Elkins, J.M, Pike, A.C.W, Mackenzie, A, Goubin, S, Strain-Damerell, C, Mahajan, P, Tallant, C, Chalk, R, Wiggers, H, Kopec, J, Fitzpatrick, F, Burgess-Brown, N, Carpenter, E.P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. 登録日 2015-08-14 公開日 2016-06-15 最終更新日 2016-10-05 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Covalent Targeting of Remote Cysteine Residues to Develop Cdk12 and Cdk13 Inhibitors. Nat.Chem.Biol., 12, 2016
5AB5	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) form-II. 分子名称: SCP2-THIOLASE LIKE PROTEIN, SULFATE ION 著者 Harijan, R.K, Kiema, T.R, Wierenga, R.K. 登録日 2015-08-01 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016
5A0N	N-terminal thioester domain of protein F2 like fibronectin-binding protein from Streptococcus pneumoniae 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PROTEIN F2 LIKE FIBRONECTIN-BINDING PROTEIN 著者 Walden, M, Edwards, J.M, Dziewulska, A.M, Kan, S.-Y, Schwarz-Linek, U, Banfield, M.J. 登録日 2015-04-21 公開日 2015-06-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An internal thioester in a pathogen surface protein mediates covalent host binding. Elife, 4, 2015
5A06	Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with sorbitol 分子名称: ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... 著者 Taberman, H, Rouvinen, J, Parkkinen, T. 登録日 2015-04-17 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.841 Å) 主引用文献 Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase. Biochem.J., 472, 2015
5A9U	Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile). 分子名称: (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, ALK TYROSINE KINASE RECEPTOR 著者 McTigue, M, Deng, Y.-L, Liu, W, Brooun, A, Stewart, A. 登録日 2015-07-22 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
5CW3	Structure of CfBRCC36-CfKIAA0157 complex (Zn Edge) 分子名称: BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B, ZINC ION 著者 Zeqiraj, E. 登録日 2015-07-27 公開日 2015-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
5CW5	Structure of CfBRCC36-CfKIAA0157 complex (QSQ mutant) 分子名称: BRCA1/BRCA2-containing complex subunit 3, Protein FAM175B 著者 Zeqiraj, E. 登録日 2015-07-27 公開日 2015-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.736 Å) 主引用文献 Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
5CSZ	CRYSTAL STRUCTURE OF GANTENERUMAB FAB FRAGMENT IN COMPLEX WITH ABETA 1-11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, GANTENERUMAB FAB FRAGMENT HEAVY CHAIN, ... 著者 Benz, J, Burger, D, Loetscher, H.R, Bohrmann, B. 登録日 2015-07-23 公開日 2015-08-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Gantenerumab: a novel human anti-Abeta antibody demonstrates sustained cerebral amyloid-Beta binding and elicits cell-mediated removal of human amyloid-Beta. J. Alzheimers Dis., 28, 2012
5CYF	Crystal structure of isoform 2 of uridine phosphorylase from Schistosoma mansoni in complex with citrate 分子名称: CITRATE ANION, Putative uridine phosphorylase 著者 Romanello, L, Torini, J.R, DeMarco, R, Pereira, H.M. 登録日 2015-07-30 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.983 Å) 主引用文献 Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
5CYG	Crystal Structure of isoform 2 of uridine phosphorylase from Schistosoma mansoni APO form 分子名称: Putative uridine phosphorylase 著者 Romanello, L, Torini, J.R, DeMarco, R, Pereira, H.M. 登録日 2015-07-30 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.017 Å) 主引用文献 Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
5DDQ	L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ 分子名称: GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DDR	L-glutamine riboswitch bound with L-glutamine soaked with Cs+ 分子名称: CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... 著者 Ren, A, Patel, D.J. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5NI3	sfGFP 204-204 mutant dimer 分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... 著者 Worthy, H.L, Rizkallah, P.J. 登録日 2017-03-23 公開日 2018-09-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Association of Fluorescent Protein Pairs and Its Significant Impact on Fluorescence and Energy Transfer Adv Sci, 2020
5D8A	Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093F empty capsid 分子名称: VP1, VP2, VP3, ... 著者 Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. 登録日 2015-08-16 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design. Nat.Struct.Mol.Biol., 22, 2015
5DDO	Structural and Dynamic Basis for Low Affinity-High Selectivity Binding of L-glutamine by the Gln-riboswitch 分子名称: L-glutamine riboswitch (58-MER), U1 small nuclear ribonucleoprotein A 著者 Ren, A, Patel, D. 登録日 2015-08-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch. Cell Rep, 13, 2015
5DDJ	Crystal structure of recombinant foot-and-mouth-disease virus O1M-S2093Y empty capsid 分子名称: Foot and mouth disease virus, VP1, VP2, ... 著者 Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. 登録日 2015-08-25 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design. Nat.Struct.Mol.Biol., 22, 2015
5CXH	SYK catalytic domain complexed with a potent orally bioavailable thiazole inhibitor 分子名称: (4R)-4-[(1R)-1-{[6-(3,4-dimethoxyphenyl)[1,3]thiazolo[5,4-c]pyridin-4-yl]oxy}ethyl]pyrrolidin-2-one, Tyrosine-protein kinase SYK 著者 Lee, C.C. 登録日 2015-07-29 公開日 2015-09-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Orally bioavailable Syk inhibitors with activity in a rat PK/PD model. Bioorg.Med.Chem.Lett., 25, 2015
5CXL	CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS 分子名称: Bifunctional hemolysin/adenylate cyclase, CALCIUM ION, NITRATE ION 著者 Motlova, L, Barinka, C, Bumba, L. 登録日 2015-07-29 公開日 2015-09-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Calcium-Driven Folding of RTX Domain beta-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts. Mol.Cell, 62, 2016
5D22	Structure of ovine granulocyte-macrophage colony-stimulating factor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Granulocyte-macrophage colony-stimulating factor 著者 Felix, J, Savvides, S.N. 登録日 2015-08-05 公開日 2016-11-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.994 Å) 主引用文献 Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF. Nat Commun, 7, 2016
5E02	Structure of RNA Helicase FRH a Critical Component of the Neurospora Crassa Circadian Clock 分子名称: ADENOSINE-5'-DIPHOSPHATE, FRQ-interacting RNA helicase, RNA (5'-R(*AP*AP*AP*A)-3') 著者 Conrad, K.S, Crane, B.C. 登録日 2015-09-28 公開日 2016-07-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of the frequency-interacting RNA helicase: a protein interaction hub for the circadian clock. Embo J., 35, 2016
5A04	Crystal structure of aldose-aldose oxidoreductase from Caulobacter crescentus complexed with glucose 分子名称: 1,4-DIETHYLENE DIOXIDE, ALDOSE-ALDOSE OXIDOREDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Taberman, H, Rouvinen, J, Parkkinen, T. 登録日 2015-04-17 公開日 2015-10-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Structure and Function of Caulobacter Crescentus Aldose-Aldose Oxidoreductase. Biochem.J., 472, 2015
5AAA	Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib 分子名称: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR 著者 McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. 登録日 2015-07-23 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016

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