4WLX
| High pressure protein crystallography of hen egg white lysozyme at 280 MPa | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Yamada, H, Nagae, T, Watanabe, N. | 登録日 | 2014-10-08 | 公開日 | 2015-04-08 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WM3
| High pressure protein crystallography of hen egg white lysozyme at 710 MPa | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Yamada, H, Nagae, T, Watanabe, N. | 登録日 | 2014-10-08 | 公開日 | 2015-04-08 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WJ9
| Structure of Human apo ALDH1A1 | 分子名称: | CHLORIDE ION, Retinal dehydrogenase 1, YTTERBIUM (III) ION | 著者 | Morgan, C.A, Hurley, T.D. | 登録日 | 2014-09-29 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1. Chem.Biol.Interact., 234, 2015
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4WKG
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4WMZ
| S. cerevisiae CYP51 complexed with fluconazole in the active site | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R, Wilbanks, S.M, Monk, B.C, Tyndall, J.D.A. | 登録日 | 2014-10-09 | 公開日 | 2015-07-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 59, 2015
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4WOJ
| Aspartate Semialdehyde Dehydrogenase from Francisella tularensis | 分子名称: | Aspartate semialdehyde dehydrogenase, SODIUM ION, SULFATE ION | 著者 | Mank, N.J, Arnette, A.K, Klapper, V.G, Chruszcz, M. | 登録日 | 2014-10-15 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of aspartate b-semialdehyde dehydrogenase from Francisella tularensis Acta Crystallogr.,Sect.F, 74, 2018
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4WPD
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7E7Z
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3D1D
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4WVY
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4NAW
| Crystal Structure of Human ATG12~ATG5-ATG16N in complex with a fragment of ATG3 | 分子名称: | Autophagy protein 5, Autophagy-related protein 16-1, SODIUM ION, ... | 著者 | Metlagel, Z, Otomo, C, Takaesu, G, Otomo, T. | 登録日 | 2013-10-22 | 公開日 | 2013-11-06 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.195 Å) | 主引用文献 | Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12. Proc.Natl.Acad.Sci.USA, 110, 2013
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3D45
| Crystal structure of mouse PARN in complex with m7GpppG | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Poly(A)-specific ribonuclease PARN | 著者 | Wu, M, Song, H. | 登録日 | 2008-05-13 | 公開日 | 2009-03-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease. Structure, 17, 2009
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6ERH
| Complex of XLF and heterodimer Ku bound to DNA | 分子名称: | DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ... | 著者 | Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B. | 登録日 | 2017-10-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nat. Struct. Mol. Biol., 25, 2018
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4WVZ
| Crystal structure of artificial crosslinked thiol dioxygenase G95C variant from Pseudomonas aeruginosa | 分子名称: | 3-mercaptopropionate dioxygenase, FE (II) ION | 著者 | Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M. | 登録日 | 2014-11-09 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa. Biochemistry, 55, 2016
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7E87
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4WY6
| Crystal structure of human BACE-1 bound to Compound 36 | 分子名称: | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... | 著者 | Vajdos, F.F. | 登録日 | 2014-11-15 | 公開日 | 2015-03-04 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design. J.Med.Chem., 58, 2015
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6EPF
| Ground state 26S proteasome (GS1) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11.8 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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7E8G
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6EPE
| Substrate processing state 26S proteasome (SPS2) | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | 登録日 | 2017-10-11 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment. Cell, 172, 2018
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4X54
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7E89
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7ELG
| LC3B modificated with a covalent probe | 分子名称: | 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | 著者 | Fan, S, Wan, W. | 登録日 | 2021-04-10 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
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6KYC
| Structure of the S207A mutant of Clostridium difficile sortase B | 分子名称: | Putative peptidase C60B, sortase B | 著者 | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | 登録日 | 2019-09-17 | 公開日 | 2020-02-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity. J.Biol.Chem., 295, 2020
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7E8B
| CryoEM structure of human Kv4.2-DPP6S complex | 分子名称: | Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2 | 著者 | Kise, Y, Nureki, O. | 登録日 | 2021-03-01 | 公開日 | 2021-10-13 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of gating modulation of Kv4 channel complexes. Nature, 599, 2021
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4NCD
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