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4WLX
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BU of 4wlx by Molmil
High pressure protein crystallography of hen egg white lysozyme at 280 MPa
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Yamada, H, Nagae, T, Watanabe, N.
登録日2014-10-08
公開日2015-04-08
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
4WM3
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BU of 4wm3 by Molmil
High pressure protein crystallography of hen egg white lysozyme at 710 MPa
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Yamada, H, Nagae, T, Watanabe, N.
登録日2014-10-08
公開日2015-04-08
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
4WJ9
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BU of 4wj9 by Molmil
Structure of Human apo ALDH1A1
分子名称: CHLORIDE ION, Retinal dehydrogenase 1, YTTERBIUM (III) ION
著者Morgan, C.A, Hurley, T.D.
登録日2014-09-29
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Chem.Biol.Interact., 234, 2015
4WKG
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BU of 4wkg by Molmil
The crystal structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic coop-erativity
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Bifunctional polymyxin resistance protein ArnA
著者Grimm, C.
登録日2014-10-02
公開日2014-12-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity.
Acta Crystallogr.,Sect.D, 71, 2015
4WMZ
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BU of 4wmz by Molmil
S. cerevisiae CYP51 complexed with fluconazole in the active site
分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE
著者Sagatova, A, Keniya, M.V, Wilson, R, Wilbanks, S.M, Monk, B.C, Tyndall, J.D.A.
登録日2014-10-09
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase.
Antimicrob.Agents Chemother., 59, 2015
4WOJ
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BU of 4woj by Molmil
Aspartate Semialdehyde Dehydrogenase from Francisella tularensis
分子名称: Aspartate semialdehyde dehydrogenase, SODIUM ION, SULFATE ION
著者Mank, N.J, Arnette, A.K, Klapper, V.G, Chruszcz, M.
登録日2014-10-15
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of aspartate b-semialdehyde dehydrogenase from Francisella tularensis
Acta Crystallogr.,Sect.F, 74, 2018
4WPD
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BU of 4wpd by Molmil
X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole
分子名称: 4-(4-fluorophenyl)-1H-imidazole, Cytochrome P450 119, PROTOPORPHYRIN IX CONTAINING FE
著者Madrona, Y.
登録日2014-10-17
公開日2015-02-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献TWO DIMENTIONAL NMR AND X-RAY ANALYSIS OF CYP119 LIGAND DEPENDENT CONFORMATIONAL DYNAMICS
To Be Published
7E7Z
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BU of 7e7z by Molmil
CryoEM structure of the human Kv4.2-KChIP1 complex, transmembrane region
分子名称: Potassium voltage-gated channel subfamily D member 2
著者Kise, Y, Nureki, O.
登録日2021-02-28
公開日2021-10-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
3D1D
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BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
4WVY
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BU of 4wvy by Molmil
Double-heterohexameric rings of full-length Rvb1(ATP)/Rvb2(apo)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Hopfner, K.-P, Lakomek, K.
登録日2014-11-08
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural Basis for Dodecameric Assembly States and Conformational Plasticity of the Full-Length AAA+ ATPases Rvb1Rvb2.
Structure, 23, 2015
4NAW
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BU of 4naw by Molmil
Crystal Structure of Human ATG12~ATG5-ATG16N in complex with a fragment of ATG3
分子名称: Autophagy protein 5, Autophagy-related protein 16-1, SODIUM ION, ...
著者Metlagel, Z, Otomo, C, Takaesu, G, Otomo, T.
登録日2013-10-22
公開日2013-11-06
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12.
Proc.Natl.Acad.Sci.USA, 110, 2013
3D45
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BU of 3d45 by Molmil
Crystal structure of mouse PARN in complex with m7GpppG
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Poly(A)-specific ribonuclease PARN
著者Wu, M, Song, H.
登録日2008-05-13
公開日2009-03-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.
Structure, 17, 2009
6ERH
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BU of 6erh by Molmil
Complex of XLF and heterodimer Ku bound to DNA
分子名称: DNA (21-MER), DNA (34-MER), Non-homologous end-joining factor 1, ...
著者Nemoz, C, Legrand, P, Ropars, V, Charbonnier, J.B.
登録日2017-10-18
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
4WVZ
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BU of 4wvz by Molmil
Crystal structure of artificial crosslinked thiol dioxygenase G95C variant from Pseudomonas aeruginosa
分子名称: 3-mercaptopropionate dioxygenase, FE (II) ION
著者Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
登録日2014-11-09
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
7E87
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BU of 7e87 by Molmil
CryoEM structure of the human Kv4.2-DPP6S complex, transmembrane and intracellular region
分子名称: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2
著者Kise, Y, Nureki, O.
登録日2021-03-01
公開日2021-10-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
4WY6
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BU of 4wy6 by Molmil
Crystal structure of human BACE-1 bound to Compound 36
分子名称: (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ...
著者Vajdos, F.F.
登録日2014-11-15
公開日2015-03-04
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design.
J.Med.Chem., 58, 2015
6EPF
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BU of 6epf by Molmil
Ground state 26S proteasome (GS1)
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
著者Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
登録日2017-10-11
公開日2018-02-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (11.8 Å)
主引用文献In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
7E8G
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BU of 7e8g by Molmil
CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, extracellular region
分子名称: Dipeptidyl aminopeptidase-like protein 6
著者Kise, Y, Nureki, O.
登録日2021-03-01
公開日2021-10-13
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
6EPE
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BU of 6epe by Molmil
Substrate processing state 26S proteasome (SPS2)
分子名称: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ...
著者Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R.
登録日2017-10-11
公開日2018-02-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (12.8 Å)
主引用文献In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
4X54
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BU of 4x54 by Molmil
Crystal structure of an oxidoreductase (short chain dehydrogenase/reductase) from Brucella ovis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Oxidoreductase, short chain dehydrogenase/reductase family
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-12-04
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of an oxidoreductase/ short chain dehydrogenase from Brucella ovis
To Be Published
7E89
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BU of 7e89 by Molmil
CryoEM structure of human Kv4.2-DPP6S complex, extracellular region
分子名称: Dipeptidyl aminopeptidase-like protein 6
著者Kise, Y, Nureki, O.
登録日2021-03-01
公開日2021-10-13
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7ELG
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BU of 7elg by Molmil
LC3B modificated with a covalent probe
分子名称: 2-methylidene-5-thiophen-2-yl-cyclohexane-1,3-dione, Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Fan, S, Wan, W.
登録日2021-04-10
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
6KYC
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BU of 6kyc by Molmil
Structure of the S207A mutant of Clostridium difficile sortase B
分子名称: Putative peptidase C60B, sortase B
著者Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y.
登録日2019-09-17
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020
7E8B
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BU of 7e8b by Molmil
CryoEM structure of human Kv4.2-DPP6S complex
分子名称: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2
著者Kise, Y, Nureki, O.
登録日2021-03-01
公開日2021-10-13
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
4NCD
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BU of 4ncd by Molmil
Crystal Structure of Class 5 Fimbriae Chaperone CfaA
分子名称: Gram-negative pili assembly chaperone, N-terminal domain protein
著者Bao, R, Xia, D.
登録日2013-10-24
公開日2014-08-27
実験手法X-RAY DIFFRACTION (2.037 Å)
主引用文献Structure of CfaA Suggests a New Family of Chaperones Essential for Assembly of Class 5 Fimbriae.
Plos Pathog., 10, 2014

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