4WKG
The crystal structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic coop-erativity
Summary for 4WKG
Entry DOI | 10.2210/pdb4wkg/pdb |
Descriptor | Bifunctional polymyxin resistance protein ArnA, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... (4 entities in total) |
Functional Keywords | arna, multi-drug resistance, mdr, polymyxin, dehydrogenase, transformylase, cooperativity, allosteric regulation, transferase |
Biological source | Escherichia coli |
Total number of polymer chains | 6 |
Total formula weight | 446741.23 |
Authors | Grimm, C. (deposition date: 2014-10-02, release date: 2014-12-17, Last modification date: 2024-01-10) |
Primary citation | Fischer, U.,Hertlein, S.,Grimm, C. The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity. Acta Crystallogr.,Sect.D, 71:687-696, 2015 Cited by PubMed: 25760615DOI: 10.1107/S1399004714026686 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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