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4WKG

The crystal structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic coop-erativity

Summary for 4WKG
Entry DOI10.2210/pdb4wkg/pdb
DescriptorBifunctional polymyxin resistance protein ArnA, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... (4 entities in total)
Functional Keywordsarna, multi-drug resistance, mdr, polymyxin, dehydrogenase, transformylase, cooperativity, allosteric regulation, transferase
Biological sourceEscherichia coli
Total number of polymer chains6
Total formula weight446741.23
Authors
Grimm, C. (deposition date: 2014-10-02, release date: 2014-12-17, Last modification date: 2024-01-10)
Primary citationFischer, U.,Hertlein, S.,Grimm, C.
The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity.
Acta Crystallogr.,Sect.D, 71:687-696, 2015
Cited by
PubMed: 25760615
DOI: 10.1107/S1399004714026686
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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