4WKG

The crystal structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic coop-erativity

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Bifunctional polymyxin resistance protein ArnA	polymer	660	74385.8	6	UniProt (P77398) Pfam (PF00551) Pfam (PF02911) Pfam (PF01370)	Escherichia coli	Polymyxin resistance protein PmrI
2	G, I (A, D)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	2	Chemie (DTT)
3	H, J (A, F)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	9	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	446314.6
Non-Polymers*	Number of molecules	4
	Total formula weight	426.6
All*	Total formula weight	446741.2

*Water molecules are not included.