PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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1HUN	SOLUTION STRUCTURE OF THE CHEMOKINE HMIP-1BETA(SLASH)ACT-2 BY MULTI-DIMENSIONAL NMR: A NOVEL CHEMOKINE DIMER 分子名称: HUMAN MACROPHAGE INFLAMMATORY PROTEIN 1 BETA 著者 Clore, G.M, Lodi, P.J, Garrett, D.S, Gronenborn, A.M. 登録日 1994-01-31 公開日 1994-04-30 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR. Science, 263, 1994
1HRM	THE PROXIMAL LIGAND VARIANT HIS93TYR OF HORSE HEART MYOGLOBIN 分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Burk, D.L, Brayer, G.D. 登録日 1994-09-21 公開日 1995-01-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The proximal ligand variant His93Tyr of horse heart myoglobin. Biochemistry, 34, 1995
3I60	Crystal structure of ERK2 bound to (S)-4-(2-(2-chlorophenylamino)-5-methylpyrimidin-4-yl)-N-(2-hydroxy-1-phenylethyl)-1H-pyrrole-2-carboxamide 分子名称: 4-{2-[(2-chlorophenyl)amino]-5-methylpyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-phenylethyl]-1H-pyrrole-2-carboxamide, Mitogen-activated protein kinase 1, SULFATE ION 著者 Jacobs, M.D, Xie, X. 登録日 2009-07-06 公開日 2010-01-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009
1HI3	Eosinophil-derived Neurotoxin (EDN) - Adenosine 2'-5'-Diphosphate Complex 分子名称: ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN 著者 Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. 登録日 2001-01-02 公開日 2001-05-31 最終更新日 2018-05-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
1UVP	Structure Of The Complex Of Porcine Pancreatic Elastase In Complex With Cadmium Refined At 1.85 A Resolution (Crystal B) 分子名称: ACETATE ION, CADMIUM ION, CHLORIDE ION, ... 著者 Weiss, M.S, Panjikar, S, Mueller-Dieckmann, C, Tucker, P.A. 登録日 2004-01-21 公開日 2004-02-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 On the Influence of the Incident Photon Energy on the Radiation Damage in Crystalline Biological Samples J.Synchrotron Radiat., 12, 2005
1HIH	COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR 分子名称: ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL, BETA-MERCAPTOETHANOL, HIV-1 PROTEASE 著者 Priestle, J.P, Gruetter, M.G. 登録日 1995-03-31 公開日 1995-07-10 最終更新日 2018-04-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor. Structure, 3, 1995
3VUK	Crystal structure of a cysteine-deficient mutant M5 in MAP kinase JNK1 分子名称: Mitogen-activated protein kinase 8, Peptide from C-Jun-amino-terminal kinase-interacting protein 1, SULFATE ION 著者 Nakaniwa, T, Kinoshita, T, Inoue, T. 登録日 2012-07-02 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Seven cysteine-deficient mutants depict the interplay between thermal and chemical stabilities of individual cysteine residues in mitogen-activated protein kinase c-Jun N-terminal kinase 1 Biochemistry, 51, 2012
2DIY	The solution structure of the thioredoxin domain of human Thioredoxin-like protein 2 分子名称: Thioredoxin-like protein 2 著者 Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-30 公開日 2007-04-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structure of the thioredoxin domain of human Thioredoxin-like protein 2 To be Published
2W1E	Structure determination of Aurora Kinase in complex with inhibitor 分子名称: 4-[(2-{4-[(PHENYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-5-YL)METHYL]MORPHOLIN-4-IUM, SERINE/THREONINE-PROTEIN KINASE 6 著者 Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. 登録日 2008-10-17 公開日 2009-01-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. J.Med.Chem., 52, 2009
2DJN	The solution structure of the homeobox domain of human Homeobox protein DLX-5 分子名称: Homeobox protein DLX-5 著者 Sasagawa, A, Ohnishi, S, Tochio, N, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-05 公開日 2006-10-05 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structure of the homeobox domain of human Homeobox protein DLX-5 To be Published
2VTM	Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H- pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design. 分子名称: CELL DIVISION PROTEIN KINASE 2, PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE 著者 Wyatt, P.G, Woodhead, A.J, Boulstridge, J.A, Berdini, V, Carr, M.G, Cross, D.M, Danillon, D, Davis, D.J, Devine, L.A, Early, T.R, Feltell, R.E, Lewis, E.J, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Reule, M, Saxty, G, Seavers, L.C.A, Smith, D, Squires, M.S, Trewartha, G, Walker, M.T, Woolford, A.J. 登録日 2008-05-15 公開日 2008-08-05 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Identification of N-(4-Piperidinyl)-4-(2,6-Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design. J.Med.Chem., 51, 2008
1UP1	UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 分子名称: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 著者 Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R. 登録日 1997-03-12 公開日 1997-09-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs. Structure, 5, 1997
2DLE	Solution structure of the fourth fn3 domain of human receptor-type tyrosine-protein phosphatase eta 分子名称: Receptor-type tyrosine-protein phosphatase eta 著者 Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-18 公開日 2006-10-18 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the fourth fn3 domain of human receptor-type tyrosine-protein phosphatase eta To be Published
1HXN	1.8 ANGSTROMS CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RABBIT SERUM HEMOPEXIN 分子名称: CHLORIDE ION, HEMOPEXIN, PHOSPHATE ION, ... 著者 Faber, H.R, Baker, E.N. 登録日 1995-06-01 公開日 1995-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 A crystal structure of the C-terminal domain of rabbit serum haemopexin. Structure, 3, 1995
2DLZ	Solution structure of the SH2 domain of human protein vav-2 分子名称: Protein vav-2 著者 Endo, H, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-20 公開日 2007-04-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH2 domain of human protein vav-2 To be Published
1HI7	NMR SOLUTION STRUCTURE OF THE DISULPHIDE-LINKED HOMODIMER OF HUMAN TFF1, 10 STRUCTURES 分子名称: PS2 PROTEIN 著者 Williams, M.A, Feeney, J. 登録日 2001-01-03 公開日 2001-01-03 最終更新日 2019-04-10 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of the Disulphide-Linked Dimeric of the Human Trefoil Protein Tff1 FEBS Lett., 493, 2001
2DMK	The solution structure of the FN3 domain of human Midline 2 protein 分子名称: midline 2 isoform 2 著者 Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-22 公開日 2006-10-22 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The solution structure of the FN3 domain of human Midline 2 protein To be Published
1HIQ	PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS 分子名称: INSULIN 著者 Hua, Q.X, Shoelson, S.E, Inouye, K, Weiss, M.A. 登録日 1993-03-05 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Paradoxical structure and function in a mutant human insulin associated with diabetes mellitus. Proc.Natl.Acad.Sci.USA, 90, 1993
2DVH	THE Y64A MUTANT OF CYTOCHROME C553 FROM DESULFOVIBRIO VULGARIS HILDENBOROUGH, NMR, 39 STRUCTURES 分子名称: CYTOCHROME C-553, HEME C 著者 Sebban-Kreuzer, C, Blackledge, M.J, Dolla, A, Marion, D, Guerlesquin, F. 登録日 1998-03-25 公開日 1998-06-17 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of ferrocytochrome c553 from Desulfovibrio vulgaris studied by NMR spectroscopy and restrained molecular dynamics. J.Mol.Biol., 245, 1995
1HN4	PROPHOSPHOLIPASE A2 DIMER COMPLEXED WITH MJ33, SULFATE, AND CALCIUM 分子名称: 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PROPHOSPHOLIPASE A2, ... 著者 Epstein, T.M, Pan, Y.H, Jain, M.K, Bahnson, B.J. 登録日 2000-12-06 公開日 2001-12-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The basis for k(cat) impairment in prophospholipase A(2) from the anion-assisted dimer structure. Biochemistry, 40, 2001
1UT0	CRYSTAL STRUCTURE OF CYTOGLOBIN: THE FOURTH GLOBIN TYPE DISCOVERED IN MAN DISPLAYS HEME HEXA-COORDINATION 分子名称: CYTOGLOBIN, HEXACYANOFERRATE(3-), PROTOPORPHYRIN IX CONTAINING FE 著者 De Sanctis, D, Dewilde, S, Pesce, A, Moens, L, Ascenzi, P, Hankeln, T, Burmester, T, Bolognesi, M. 登録日 2003-12-02 公開日 2004-06-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Cytoglobin: The Fourth Globin Type Discovered in Man Displays Heme Hexa-Coordination J.Mol.Biol., 336, 2004
3HUC	Human p38 MAP Kinase in Complex with RL40 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mitogen-activated protein kinase 14, N-[2-phenyl-4-(1H-pyrazol-3-ylamino)quinazolin-7-yl]prop-2-enamide, ... 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2009-06-13 公開日 2010-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fluorophore labeling of the glycine-rich loop as a method of identifying inhibitors that bind to active and inactive kinase conformations. J.Am.Chem.Soc., 132, 2010
1V07	CRYSTAL STRUCTURE OF ThrE11Val mutant of THE NERVE TISSUE MINI-HEMOGLOBIN FROM THE NEMERTEAN WORM CEREBRATULUS LACTEUS 分子名称: NEURAL HEMOGLOBIN, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Pesce, A, Nardini, M, Ascenzi, P, Geuens, E, Dewilde, S, Moens, L, Bolognesi, M, Riggs, A, Hale, A, Deng, P, Nienhaus, G.U, Olson, J.S, Nienhaus, K. 登録日 2004-03-24 公開日 2004-06-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Thr-E11 Regulates O2 Affinity in Cerebratulus Lacteus Mini-Hemoglobin J.Biol.Chem., 279, 2004
3HV7	Human p38 MAP Kinase in Complex with RL38 分子名称: 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2009-06-15 公開日 2009-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Displacement assay for the detection of stabilizers of inactive kinase conformations. J.Med.Chem., 53, 2010
2XKE	Structure of Nek2 bound to Aminipyrazine Compound 5 分子名称: 1-[3-amino-6-(3-methoxyphenyl)pyrazin-2-yl]piperidine-4-carboxylic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 著者 Mas-Droux, C, Bayliss, R. 登録日 2010-07-07 公開日 2010-11-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010

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