3M4A
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![BU of 3m4a by Molmil](/molmil-images/mine/3m4a) | Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site | 分子名称: | ACETIC ACID, DNA (5'-D(*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*CP*CP*TP*TP*AP*TP*TP*C)-3'), ... | 著者 | Patel, A, Yakovleva, L, Shuman, S, Mondragon, A. | 登録日 | 2010-03-10 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site. Structure, 18, 2010
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7PVB
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3M4O
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![BU of 3m4o by Molmil](/molmil-images/mine/3m4o) | RNA polymerase II elongation complex B | 分子名称: | DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | 登録日 | 2010-03-11 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | 主引用文献 | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
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7PUE
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![BU of 7pue by Molmil](/molmil-images/mine/7pue) | Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine inhibitor 3a | 分子名称: | 6-[4-[[2,3-bis(chloranyl)phenyl]sulfonylamino]phenyl]-~{N}-[(3~{R})-pyrrolidin-3-yl]-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide, GLYCEROL, Serine/threonine-protein kinase Sgk1 | 著者 | Dreyer, M.K, Halland, N, Nazare, M. | 登録日 | 2021-09-29 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J.Med.Chem., 65, 2022
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5AVW
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![BU of 5avw by Molmil](/molmil-images/mine/5avw) | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 16.5 min | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | 登録日 | 2015-07-01 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography. Nat Commun, 6, 2015
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3MRI
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![BU of 3mri by Molmil](/molmil-images/mine/3mri) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant To be Published
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3MRN
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![BU of 3mrn by Molmil](/molmil-images/mine/3mrn) | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS4b-1807-1816 decapeptide | 分子名称: | 10-meric peptide from Genome polyprotein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Chouquet, A, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS4b-1807-1816 decapeptide To be Published
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5AW8
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![BU of 5aw8 by Molmil](/molmil-images/mine/5aw8) | Kinetics by X-ray crystallography: E2.MgF42-.2RB+ crystal | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Ogawa, H, Cornelius, F, Hirata, A, Toyoshima, C. | 登録日 | 2015-07-01 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Sequential substitution of K(+) bound to Na(+),K(+)-ATPase visualized by X-ray crystallography. Nat Commun, 6, 2015
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7JQZ
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7JQY
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4BC3
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![BU of 4bc3 by Molmil](/molmil-images/mine/4bc3) | Crystal structure of human D-xylulokinase | 分子名称: | 1,2-ETHANEDIOL, XYLULOSE KINASE | 著者 | Bunker, R.D, Loomes, K.M, Baker, E.N. | 登録日 | 2012-10-01 | 公開日 | 2012-11-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4AWP
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4ATV
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![BU of 4atv by Molmil](/molmil-images/mine/4atv) | STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH | 分子名称: | DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION | 著者 | Drew, D, Lee, C, Iwata, S, Cameron, A.D. | 登録日 | 2012-05-10 | 公開日 | 2013-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights. J. Gen. Physiol., 144, 2014
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7JQX
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3M0J
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![BU of 3m0j by Molmil](/molmil-images/mine/3m0j) | Structure of oxaloacetate acetylhydrolase in complex with the inhibitor 3,3-difluorooxalacetate | 分子名称: | 2,2-difluoro-3,3-dihydroxybutanedioic acid, CALCIUM ION, MANGANESE (II) ION, ... | 著者 | Herzberg, O, Chen, C. | 登録日 | 2010-03-03 | 公開日 | 2010-06-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure of oxalacetate acetylhydrolase, a virulence factor of the chestnut blight fungus. J.Biol.Chem., 285, 2010
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3M8Y
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![BU of 3m8y by Molmil](/molmil-images/mine/3m8y) | Phosphopentomutase from Bacillus cereus after glucose-1,6-bisphosphate activation | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | 著者 | Panosian, T.D, Nannemann, D.P, Watkins, G, Wadzinski, B, Bachmann, B.O, Iverson, T.M. | 登録日 | 2010-03-19 | 公開日 | 2010-12-29 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Bacillus cereus Phosphopentomutase Is an Alkaline Phosphatase Family Member That Exhibits an Altered Entry Point into the Catalytic Cycle. J.Biol.Chem., 286, 2011
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3MHS
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![BU of 3mhs by Molmil](/molmil-images/mine/3mhs) | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ... | 著者 | Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C. | 登録日 | 2010-04-08 | 公開日 | 2010-04-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural insights into the assembly and function of the SAGA deubiquitinating module. Science, 328, 2010
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7MYF
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![BU of 7myf by Molmil](/molmil-images/mine/7myf) | Ubiquitin variant UbV.k.1 in complex with Ube2k | 分子名称: | Ubiquitin, Ubiquitin variant UbV.k.1, Ubiquitin-conjugating enzyme E2 K | 著者 | Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. | 登録日 | 2021-05-21 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
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7PS3
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![BU of 7ps3 by Molmil](/molmil-images/mine/7ps3) | Crystal structure of antibody Beta-32 Fab | 分子名称: | Beta-32 heavy chain, Beta-32 light chain, CHLORIDE ION, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-09-22 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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3MCJ
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![BU of 3mcj by Molmil](/molmil-images/mine/3mcj) | Crystal structure of molybdenum cofactor biosynthesis (AQ_061) other form from aquifex aeolicus VF5 | 分子名称: | 1,2-ETHANEDIOL, Molybdenum cofactor biosynthesis MOG | 著者 | Jeyakanthan, J, Kanaujia, S.P, Sekar, K, Agari, Y, Ebihara, A, Kuramitsu, S, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-03-29 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures, dynamics and functional implications of molybdenum-cofactor biosynthesis protein MogA from two thermophilic organisms Acta Crystallogr.,Sect.F, 67, 2011
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5TLQ
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![BU of 5tlq by Molmil](/molmil-images/mine/5tlq) | Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex | 分子名称: | 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA | 著者 | Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S. | 登録日 | 2016-10-11 | 公開日 | 2017-04-12 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
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3ML0
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![BU of 3ml0 by Molmil](/molmil-images/mine/3ml0) | Thermostable Penicillin G acylase from Alcaligenes faecalis in tetragonal form | 分子名称: | CALCIUM ION, Penicillin G acylase, alpha subunit, ... | 著者 | Varshney, N.K, Kumar, R.S, Ignatova, Z, Dodson, E, Suresh, C.G. | 登録日 | 2010-04-16 | 公開日 | 2010-05-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis. Acta Crystallogr.,Sect.F, 68, 2012
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7PS0
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![BU of 7ps0 by Molmil](/molmil-images/mine/7ps0) | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with beta-24 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-24 heavy chain, Beta-24 light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-09-22 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7MYH
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![BU of 7myh by Molmil](/molmil-images/mine/7myh) | Ubiquitin variant UbV.k.2 in complex with Ube2k | 分子名称: | GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K | 著者 | Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S. | 登録日 | 2021-05-21 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k. Acs Chem.Biol., 16, 2021
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7PRY
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![BU of 7pry by Molmil](/molmil-images/mine/7pry) | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with COVOX-45 and beta-6 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-6 Fab heavy chain, Beta-6 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-09-22 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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