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7BWD
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BU of 7bwd by Molmil
Structure of Dot1L-H2BK34ub Nucleosome Complex
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Lou, Z.Y, Liu, L, Cao, L, Ai, H.S, Sun, Z.X.
登録日2020-04-14
公開日2021-04-14
実験手法ELECTRON MICROSCOPY (4.32 Å)
主引用文献Structure of the Dot1L-H2BK34ub Nucleosome Complex Reveals an Unprecedented Crosstalk Activation Mechanism through Nucleosome Shape Distortion
To Be Published
6TRL
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BU of 6trl by Molmil
Human Eg5 motor domain mutant Y82F
分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Kinesin-like protein KIF11, ...
著者Garcia-Saez, I, Skoufias, D.A.
登録日2019-12-19
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human Eg5 motor domain mutant Y82F
To Be Published
6TLE
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BU of 6tle by Molmil
Human Eg5 motor domain mutant E344K
分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ...
著者Garcia-Saez, I, Skoufias, D.A.
登録日2019-12-02
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Human Eg5 motor domain mutant E344K
To Be Published
6CBI
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BU of 6cbi by Molmil
PCNA in complex with inhibitor
分子名称: GLY-ARG-LYS-ARG-ARG-GLN-DAB-SER-MET-THR-GLU-PHE-TYR-HIS, Proliferating cell nuclear antigen, SULFATE ION
著者Bruning, J.B, Wegener, K.L.
登録日2018-02-03
公開日2018-07-04
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CCD
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BU of 6ccd by Molmil
The crystal structure of Mycobacterium tuberculosis Rv1747 FHA-1
分子名称: ABC transporter ATP-binding/permease protein Rv1747, SULFATE ION
著者Gay, L.M, Gee, C.L, Alber, T.
登録日2018-02-06
公開日2018-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747.
Structure, 26, 2018
8A8N
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BU of 8a8n by Molmil
Structure of self-assembling engineered protein nanocage (EPN) fused with hepatitis A pX protein
分子名称: EPN-pX
著者Duyvesteyn, H.M.E, Stuart, D.I.
登録日2022-06-23
公開日2022-08-10
最終更新日2022-08-31
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.
Plos Pathog., 18, 2022
6CF6
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BU of 6cf6 by Molmil
RNF146 TBM-Tankyrase ARC2-3 complex
分子名称: RNF146, Tankyrase-1
著者Da Rosa, P.A, Xu, W.
登録日2018-02-13
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural basis for tankyrase-RNF146 interaction reveals noncanonical tankyrase-binding motifs.
Protein Sci., 27, 2018
6CPI
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BU of 6cpi by Molmil
Solution structure of SH3 domain from Shank1
分子名称: SH3 and multiple ankyrin repeat domains protein 1
著者Ishida, H, Vogel, H.J.
登録日2018-03-13
公開日2018-08-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels.
FEBS Lett., 592, 2018
6UMA
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BU of 6uma by Molmil
Crystal structure of the TRIM7 B30.2 domain at 1.6 angstrom resolution
分子名称: E3 ubiquitin-protein ligase TRIM7, GLYCEROL, MALONATE ION
著者Munoz Sosa, C.J, Carrizo, M.E.
登録日2019-10-09
公開日2021-04-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1.
J.Biol.Chem., 296, 2021
6UMB
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BU of 6umb by Molmil
Crystal structure of TRIM7 B30.2 domain at 1.8 angstrom resolution
分子名称: BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase TRIM7, MALONATE ION
著者Munoz Sosa, C.J, Carrizo, M.E.
登録日2019-10-09
公開日2021-04-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1.
J.Biol.Chem., 296, 2021
8BXU
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BU of 8bxu by Molmil
Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with MPD (2-Methyl-2,4-pentanediol)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-ETHOXYETHANOL, Odorant binding protein, ...
著者Liggri, P.G.V, Tsitsanou, K.E, Zographos, S.E.
登録日2022-12-09
公開日2023-03-22
最終更新日2023-04-12
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies.
Int.J.Biol.Macromol., 237, 2023
8BXV
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BU of 8bxv by Molmil
Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with Thymol
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-METHYL-2-(1-METHYLETHYL)PHENOL, DI(HYDROXYETHYL)ETHER, ...
著者Liggri, P.G.V, Tsitsanou, K.E, Zographos, S.E.
登録日2022-12-10
公開日2023-03-22
最終更新日2023-04-12
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies.
Int.J.Biol.Macromol., 237, 2023
7D3E
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BU of 7d3e by Molmil
Cryo-EM structure of human DUOX1-DUOXA1 in low-calcium state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, L, Wu, J.X.
登録日2020-09-19
公開日2020-12-09
最終更新日2021-06-23
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of human dual oxidase 1 complex in low-calcium and high-calcium states.
Nat Commun, 12, 2021
6UYO
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BU of 6uyo by Molmil
Crystal structure of K37-acetylated SUMO1 in complex with PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.639 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYX
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BU of 6uyx by Molmil
Crystal structure of K37-acetylated SUMO1 in complex with phosphorylated DAXX
分子名称: Small ubiquitin-related modifier 1, phosphorylated DAXX
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6T7A
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BU of 6t7a by Molmil
Structure of human Sox11 transcription factor in complex with a nucleosome
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
登録日2019-10-21
公開日2020-04-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
7CXN
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BU of 7cxn by Molmil
Architecture of a SARS-CoV-2 mini replication and transcription complex
分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ...
著者Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z.
登録日2020-09-02
公開日2020-11-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Architecture of a SARS-CoV-2 mini replication and transcription complex.
Nat Commun, 11, 2020
6T7B
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BU of 6t7b by Molmil
Structure of human Sox2 transcription factor in complex with a nucleosome
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
登録日2019-10-21
公開日2020-04-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
6T9K
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BU of 6t9k by Molmil
SAGA Core module
分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
著者Wang, H, Cheung, A, Cramer, P.
登録日2019-10-28
公開日2020-01-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6TKQ
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BU of 6tkq by Molmil
Tankyrase 2 in complex with an inhibitor (OM-2700)
分子名称: Tankyrase-2, ZINC ION, ~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-phenyl-1,2,4-triazol-3-yl]cyclobutyl]-1,5-naphthyridine-4-carboxamide
著者Sowa, S.T, Lehtio, L.
登録日2019-11-28
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor.
J.Med.Chem., 63, 2020
1Y7N
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BU of 1y7n by Molmil
Solution structure of the second PDZ domain of the human neuronal adaptor X11alpha
分子名称: Amyloid beta A4 precursor protein-binding family A member 1
著者Duquesne, A.E, de Ruijter, M, Brouwer, J, Drijfhout, J.W, Nabuurs, S.B, Spronk, C.A.E.M, Vuister, G.W, Ubbink, M, Canters, G.W.
登録日2004-12-09
公開日2005-11-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second PDZ domain of the neuronal adaptor X11alpha and its interaction with the C-terminal peptide of the human copper chaperone for superoxide dismutase
J.Biomol.Nmr, 32, 2005
6TCA
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BU of 6tca by Molmil
Phosphorylated p38 and MAPKAPK2 complex with inhibitor
分子名称: MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide
著者Sok, P, Remenyi, A.
登録日2019-11-05
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases.
Structure, 28, 2020
1BMC
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BU of 1bmc by Molmil
STRUCTURE OF A ZINC METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS
分子名称: METALLO-BETA-LACTAMASE, ZINC ION
著者Carfi, A, Pares, S, Duee, E, Dideberg, O.
登録日1995-06-16
公開日1996-08-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold.
EMBO J., 14, 1995
7YFV
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BU of 7yfv by Molmil
Structure of Rpgrip1l CC1
分子名称: Protein fantom
著者He, R, Chen, G, Li, Z, Li, J.
登録日2022-07-09
公開日2023-05-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023
7YFU
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BU of 7yfu by Molmil
Structure of Rpgrip1l CC2
分子名称: Protein fantom
著者He, R, Chen, G, Li, Z, Li, J.
登録日2022-07-09
公開日2023-05-17
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the N-terminal coiled-coil domains of the ciliary protein Rpgrip1l.
Iscience, 26, 2023

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