8A8N

Structure of self-assembling engineered protein nanocage (EPN) fused with hepatitis A pX protein

Summary for 8A8N

Entry DOI	10.2210/pdb8a8n/pdb
EMDB information	15234
Descriptor	EPN-pX (1 entity in total)
Functional Keywords	hepatitis a, px, vp1-px, nanocage, icosahedral, protein nanoparticle, virus assembly, enveloped viruses, structural protein
Biological source	Human immunodeficiency virus type 1 BH10 More
Total number of polymer chains	1
Total formula weight	32934.23
Authors	Duyvesteyn, H.M.E.,Stuart, D.I. (deposition date: 2022-06-23, release date: 2022-08-10, Last modification date: 2022-08-31)
Primary citation	Shirasaki, T.,Feng, H.,Duyvesteyn, H.M.E.,Fusco, W.G.,McKnight, K.L.,Xie, L.,Boyce, M.,Kumar, S.,Barouch-Bentov, R.,Gonzalez-Lopez, O.,McNamara, R.,Wang, L.,Hertel-Wulff, A.,Chen, X.,Einav, S.,Duncan, J.A.,Kapustina, M.,Fry, E.E.,Stuart, D.I.,Lemon, S.M. Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX. Plos Pathog., 18:e1010543-e1010543, 2022 Cited by PubMed: 35969644 DOI: 10.1371/journal.ppat.1010543 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.7 Å)

Structure validation