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1ZSA
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CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM
分子名称: CARBONIC ANHYDRASE II
著者Lesburg, C.A, Christianson, D.W.
登録日1996-01-09
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
Biochemistry, 35, 1996
1ZNC
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HUMAN CARBONIC ANHYDRASE IV
分子名称: CARBONIC ANHYDRASE IV, SULFATE ION, ZINC ION
著者Stams, T, Christianson, D.W.
登録日1996-09-17
公開日1997-09-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1ZH9
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carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE, Carbonic anhydrase II, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-23
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献carbonic anhydrase II in complex with N-4-Methyl-1-piperazinyl-N'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor
To be Published
1ZGF
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carbonic anhydrase II in complex with trichloromethiazide as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE, Carbonic anhydrase II, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-21
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献carbonic anhydrase II in complex with trichloromethiazide as sulfonamide inhibitor
To be Published
1ZGE
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carbonic anhydrase II in complex with p-Sulfonamido-o,o'-dichloroaniline as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-AMINO-3,5-DICHLOROBENZENESULFONAMIDE, Carbonic anhydrase II, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-21
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献carbonic anhydrase II in complex with p-Sulfonamido-o,o'-dichloroaniline as sulfonamide inhibitor
To be Published
1ZFQ
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carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE, Carbonic anhydrase II, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-20
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献carbonic anhydrase II in complex with ethoxzolamidphenole as sulfonamide inhibitor
To be Published
1ZFK
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carbonic anhydrase II in complex with N-4-sulfonamidphenyl-N'-4-methylbenzosulfonylurease as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase II, GLYCEROL, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-20
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献carbonic anhydrase II in complex with N-4-sulfonamidphenyl-N'-4-methylbenzosulfonylurease as sulfonamide inhibitor
To be Published
1ZE8
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Carbonic anhydrase II in complex with a membrane-impermeant sulfonamide inhibitor
分子名称: 1-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}-2,4,6-TRIMETHYLPYRIDINIUM, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase II, ...
著者Menchise, V, De Simone, G, Alterio, V, Di Fiore, A, Pedone, C, Scozzafava, A, Supuran, C.T.
登録日2005-04-18
公開日2005-10-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II
J.Med.Chem., 48, 2005
1Z9Y
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carbonic anhydrase II in complex with furosemide as sulfonamide inhibitor
分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Carbonic anhydrase II, ...
著者Honndorf, V.S, Heine, A, Klebe, G, Supuran, C.T.
登録日2005-04-05
公開日2006-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献carbonic anhydrase II in complex with furosemide as sulfonamide inhibitor
To be Published
1Z97
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Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer.
分子名称: Carbonic anhydrase III, ZINC ION
著者Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1Z93
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Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer.
分子名称: Carbonic anhydrase III, ZINC ION
著者Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R.
登録日2005-03-31
公開日2005-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
Biochemistry, 44, 2005
1YO2
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Proton Transfer from His200 in Human Carbonic Anhydrase II
分子名称: Carbonic anhydrase II, ZINC ION
著者Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YO1
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Proton Transfer from His200 in Human Carbonic Anhydrase II
分子名称: Carbonic anhydrase II, SULFATE ION, ZINC ION
著者Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YO0
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Proton Transfer from His200 in Human Carbonic Anhydrase II
分子名称: CHLORIDE ION, Carbonic anhydrase II, ZINC ION
著者Bhatt, D, Tu, C, Fisher, S.Z, Hernandez Prada, J.A, McKenna, R, Silverman, D.N.
登録日2005-01-26
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Proton transfer in a Thr200His mutant of human carbonic anhydrase II
Proteins, 61, 2005
1YDD
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STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Nair, S.K, Christianson, D.W.
登録日1994-12-22
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
1YDC
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STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1994-12-22
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
1YDB
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BU of 1ydb by Molmil
STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Nair, S.K, Christianson, D.W.
登録日1994-12-22
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
1YDA
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BU of 1yda by Molmil
STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Nair, S.K, Christianson, D.W.
登録日1994-12-22
公開日1995-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
1XQ0
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Structure of human carbonic anhydrase II with 4-[(3-bromo-4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4]-triazole
分子名称: 2-BROMO-4-{[(4-CYANOPHENYL)(4H-1,2,4-TRIAZOL-4-YL)AMINO]METHYL}PHENYL SULFAMATE, Carbonic anhydrase II, ZINC ION
著者Lloyd, M.D, Thiyagarajan, N, Ho, Y.T, Woo, L.W.L, Sutcliffe, O.B, Purohit, A, Reed, M.J, Acharya, K.R, Potter, B.V.L.
登録日2004-10-11
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,)
Biochemistry, 44, 2005
1XPZ
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Structure of human carbonic anhydrase II with 4-[4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4]-triazole
分子名称: 4-{[(4-CYANOPHENYL)(4H-1,2,4-TRIAZOL-4-YL)AMINO]METHYL}PHENYL SULFAMATE, Carbonic anhydrase II, ZINC ION
著者Lloyd, M.D, Thiyagarajan, N, Ho, Y.T, Woo, L.W.L, Sutcliffe, O.B, Purohit, A, Reed, M.J, Acharya, K.R, Potter, B.V.L.
登録日2004-10-11
公開日2005-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,)
Biochemistry, 44, 2005
1XEV
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Crystal structure of human carbonic anhydrase II in a new crystal form
分子名称: Carbonic anhydrase II, ZINC ION
著者Mazumdar, P.A, Kumaran, D, Das, A.K, Swaminathan, S.
登録日2004-09-13
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human carbonic anhydrase II in a new crystal form
To be Published
1XEG
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Crystal structure of human carbonic anhydrase II complexed with an acetate ion
分子名称: ACETATE ION, Carbonic anhydrase II, ZINC ION
著者Mazumdar, P.A, Kumaran, D, Das, A.K, Swaminathan, S.
登録日2004-09-10
公開日2005-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A novel acetate-bound complex of human carbonic anhydrase II.
Acta Crystallogr.,Sect.F, 64, 2008
1V9I
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Crystal Structure Analysis of the site specific mutant (Q253C) of bovine carbonic anhydrase II
分子名称: Carbonic anhydrase II, ZINC ION
著者Saito, R, Sato, T, Ikai, A, Tanaka, N.
登録日2004-01-26
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure Analysis of the site specific mutant (Q253C) of bovine carbonic anhydrase II
To be Published
1V9E
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Crystal Structure Analysis of Bovine Carbonic Anhydrase II
分子名称: Carbonic anhydrase II, ZINC ION
著者Saito, R, Sato, T, Ikai, A, Tanaka, N.
登録日2004-01-26
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of bovine carbonic anhydrase II at 1.95 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
1URT
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MURINE CARBONIC ANHYDRASE V
分子名称: CARBONIC ANHYDRASE V, ZINC ION
著者Boriack-Sjodin, P.A, Christianson, D.W.
登録日1996-07-03
公開日1997-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V.
Biochemistry, 35, 1996

223532

件を2024-08-07に公開中

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