PDB: 1373 件ウェブページステータス検索Chemie searchBIRD

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3A4G	Structure of cytochrome P450 vdh from Pseudonocardia autotrophica (trigonal crystal form) 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, PROTOPORPHYRIN IX CONTAINING FE, Vitamin D hydroxylase 著者 Yasutake, Y, Fujii, Y, Cheon, W.K, Arisawa, A, Tamura, T. 登録日 2009-07-07 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase J.Biol.Chem., 285, 2010
2ZWT	Crystal Structure of Ferric Cytochrome P450cam 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... 著者 Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. 登録日 2008-12-18 公開日 2009-02-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Substrate binding induces structural changes in cytochrome P450cam Acta Crystallogr.,Sect.F, 65, 2009
3A4Z	Structure of cytochrome P450 Vdh mutant (Vdh-K1) obtained by directed evolution 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Yasutake, Y, Fujii, Y, Cheon, W.K, Arisawa, A, Tamura, T. 登録日 2009-07-24 公開日 2010-07-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural evidence for enhancement of sequential vitamin D3 hydroxylation activities by directed evolution of cytochrome P450 vitamin D3 hydroxylase J.Biol.Chem., 285, 2010
3ABA	Crystal structure of CYP105P1 in complex with filipin I 分子名称: (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,28R)-3-hexyl-4,6,8,10,12,14,16-heptahydroxy-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Xu, L.H, Fushinobu, S, Takamatsu, S, Wakagi, T, Ikeda, H, Shoun, H. 登録日 2009-12-04 公開日 2010-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis J.Biol.Chem., 285, 2010
4IPS	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazin-2-one, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, LeDu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IPW	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(3,4-dihydroxybenzyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IQ7	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-methylpiperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
2Y98	Structure of the mixed-function P450 MycG in complex with mycinamicin IV in P21212 space group 分子名称: CHLORIDE ION, GLYCEROL, MYCINAMICIN IV, ... 著者 Li, S, Kells, P.M, Sherman, D.H, Podust, L.M. 登録日 2011-02-12 公開日 2012-02-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions. J.Biol.Chem., 287, 2012
4IQ9	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
7XBO	Crystal Structure of 10-dml-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 分子名称: (3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, Cytochrome P450 monooxygenase PikC, DI(HYDROXYETHYL)ETHER, ... 著者 Li, G.B, Pan, Y.J, Li, S.Y, Gao, X. 登録日 2022-03-21 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 New mechanistic insight of cytochrome P450 PikC gained from site-specific mutagenesis by non-coding amino acids Nat Commun, 2023
7XBN	Crystal Structure of YC-17-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 分子名称: 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, Cytochrome P450 monooxygenase PikC, DI(HYDROXYETHYL)ETHER, ... 著者 Li, G.B, Pan, Y.J, Li, S.Y, Gao, X. 登録日 2022-03-21 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 New mechanistic insight of cytochrome P450 PikC gained from site-specific mutagenesis by non-coding amino acids Nat Commun, 2023
7WZM	Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis in complex with Oleic acid 分子名称: OLEIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Kim, V.C, Kim, D.G, Lee, S.G, Lee, G.H, Lee, S.A, Kang, L.W. 登録日 2022-02-18 公開日 2023-02-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis in complex with Oleic acid To Be Published
7XBM	Crystal Structure of cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 分子名称: CACODYLATE ION, Cytochrome P450 monooxygenase PikC, DI(HYDROXYETHYL)ETHER, ... 著者 Li, G.B, Pan, Y.J, Li, S.Y, Gao, X. 登録日 2022-03-21 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 Nat Commun, 2023
7WZL	Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Kim, V.C, Kim, D.G, Lee, S.G, Lee, G.H, Lee, S.A, Kang, L.W. 登録日 2022-02-18 公開日 2023-02-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of Cytochrome P450 184A1 from streptomyces avermitilis To Be Published
7X2Q	Salvia miltiorrhiza CYP76AH3 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Sugiol synthase 著者 Chang, Z. 登録日 2022-02-26 公開日 2023-03-01 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structure of CYP76AH3 at 3.67 Angstroms resolution To Be Published
7X53	cytochrome P450 monooxygenase 分子名称: Cytochrome P450 family protein, PROTOPORPHYRIN IX CONTAINING FE 著者 Yan, Y, Zheng, C. 登録日 2022-03-03 公開日 2023-03-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structure of cytochrome P450 monooxygenase at 3.35 Angstroms resolution. To Be Published
3B99	Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1) in complex with substrate analog U51605 分子名称: (5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-oct-1-en-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}hept-5-enoic acid, PROTOPORPHYRIN IX CONTAINING FE, Prostaglandin I2 synthase 著者 Li, Y.-C, Chiang, C.-W, Yeh, H.-C, Hsu, P.-Y, Whitby, F.G, Wang, L.-H, Chan, N.-L. 登録日 2007-11-03 公開日 2007-11-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283, 2008
3BE0	The Role of Asn 242 in P450cin 分子名称: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE 著者 Meharenna, Y.T, Poulos, T.L. 登録日 2007-11-15 公開日 2008-02-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 The critical role of substrate-protein hydrogen bonding in the control of regioselective hydroxylation in p450cin J.Biol.Chem., 283, 2008
7Y9J	Crystal structure of P450 BM3-TMK from Bacillus megaterium in complex with 5-nitro-1,2-benzisoxazole 分子名称: 5-nitro-1,2-benzoxazole, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. 登録日 2022-06-24 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Engineering of a P450-based Kemp eliminase with a new mechanism Chinese J Catal, 47, 2023
7Y9K	Crystal structure of P450 BM3-TMK from Bacillus megaterium 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Wang, Q, Zhang, L.L, Liu, W.D, Huang, J.-W, Yang, Y, Chen, C.-C, Guo, R.-T. 登録日 2022-06-25 公開日 2023-06-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Engineering of a P450-based Kemp eliminase with a new mechanism Chinese J Catal, 47, 2023
4J14	Crystal Structure of Human Cytochrome P450 CYP46A1 with Posaconazole Bound 分子名称: Cholesterol 24-hydroxylase, GLYCEROL, POSACONAZOLE, ... 著者 Stout, C.D, Mast, N, Pikuleva, I.A. 登録日 2013-01-31 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1. Mol.Pharmacol., 84, 2013
2ZBX	Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (wild type) with imidazole bound 分子名称: Cytochrome P450-SU1, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. 登録日 2007-10-30 公開日 2008-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
2ZBZ	Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE 著者 Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T. 登録日 2007-10-30 公開日 2008-04-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3 Biochemistry, 47, 2008
2ZAW	Crystal Structure of Ferric Cytochrome P450cam Reconstituted with 6-Methyl-6-depropionated Hemin 分子名称: 6-METHY-6-DEPROPIONATEHEMIN, CAMPHOR, CHLORIDE ION, ... 著者 Harada, K, Sakurai, K, Shimada, H, Tsukihara, T, Hayashi, T. 登録日 2007-10-11 公開日 2008-01-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam J.Am.Chem.Soc., 130, 2008
2ZQX	Cytochrome P450BSbeta cocrystallized with heptanoic acid 分子名称: Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. 登録日 2008-08-22 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis. J.Biol.Inorg.Chem., 2010

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