7XBO

Crystal Structure of 10-dml-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238

Summary for 7XBO

• Entry DOI: 10.2210/pdb7xbo/pdb
• Descriptor: Cytochrome P450 monooxygenase PikC, PROTOPORPHYRIN IX CONTAINING FE, (3R,4S,5S,7R,9E,11R,12R)-12-ETHYL-4-HYDROXY-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, ... (6 entities in total)
• Functional Keywords: oxidoreductase, 10-dml-bound, pikc, unnatural amino acid
• Biological source: Streptomyces venezuelae
• Total number of polymer chains: 2
• Total formula weight: 101556.67

Authors

Li, G.B.,Pan, Y.J.,Li, S.Y.,Gao, X. (deposition date: 2022-03-21, release date: 2023-02-15, Last modification date: 2023-11-29)

• Primary citation: Pan, Y.J.,Li, G.B.,Gao, X.,Li, S.Y.; New mechanistic insight of cytochrome P450 PikC gained from site-specific mutagenesis by non-coding amino acids; Nat Commun, 2023

Experimental method

X-RAY DIFFRACTION (2.2 Å)