8U17
 
 | | The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-long bound to Pomalidomide | | 分子名称: | DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | | 登録日 | 2023-08-30 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
Sci Rep, 13, 2023
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8U15
 | | The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-short bound to CC-220 | | 分子名称: | (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DDB1, Protein cereblon, ... | | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | | 登録日 | 2023-08-30 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
Sci Rep, 13, 2023
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8QDW
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8QDP
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8QDS
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8QE7
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8QDT
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8W7G
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8U0V
 | | S. cerevisiae Pex1/Pex6 with 1 mM ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Peroxisomal ATPase PEX1, Peroxisomal ATPase PEX6 | | 著者 | Gardner, B.M. | | 登録日 | 2023-08-29 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | The N1 domain of the peroxisomal AAA-ATPase Pex6 is required for Pex15 binding and proper assembly with Pex1.
J.Biol.Chem., 300, 2023
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8U0Q
 | | Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series | | 分子名称: | Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Dementiev, A.A, Michino, M, Vendome, J, Ginn, J, Bryk, R, Olland, A. | | 登録日 | 2023-08-29 | | 公開日 | 2024-01-03 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Shape-Based Virtual Screening of a Billion-Compound Library Identifies Mycobacterial Lipoamide Dehydrogenase Inhibitors.
Acs Bio Med Chem Au, 3, 2023
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8QDE
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8QDK
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8W6I
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8W6J
 | | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Li, J, Xu, X, He, Y, Luo, M. | | 登録日 | 2023-08-29 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc
To Be Published
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8W6K
 | | in situ room temperature Laue crystallography | | 分子名称: | Lysozyme C | | 著者 | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | | 登録日 | 2023-08-29 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF
Nucl.Sci.Tech., 35, 2024
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8QCU
 | | Lysozyme covalently bound to fac-[Re(CO)3-imidazole] complex, incubated for 38 weeks. | | 分子名称: | BROMIDE ION, CHLORIDE ION, IMIDAZOLE, ... | | 著者 | Jacobs, F.J.F, Brink, A, Helliwell, J.R. | | 登録日 | 2023-08-28 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Time-series analysis of rhenium(I) organometallic covalent binding to a model protein for drug development.
Iucrj, 11, 2024
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8U02
 | | CryoEM structure of D2 dopamine receptor in complex with GoA KE mutant and dopamine | | 分子名称: | D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Krumm, B.E, Kapolka, N.J, Fay, J.F, Roth, B.L. | | 登録日 | 2023-08-28 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Nat Commun, 15, 2024
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8QCW
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8TZL
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8TZK
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8TZJ
 | | Cryo-EM structure of Vibrio cholerae FtsE/FtsX complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Hao, A, Lee, S.-Y. | | 登録日 | 2023-08-27 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae.
Structure, 32, 2024
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8TZQ
 | | CryoEM structure of D2 dopamine receptor in complex with GoA KE Mutant, scFv16, and dopamine | | 分子名称: | D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Krumm, B.E, Kapolka, N.J, Fay, J.F, Roth, B.L. | | 登録日 | 2023-08-27 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Nat Commun, 15, 2024
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8QCI
 | | FCGBP D10 Assembly Segment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | | 著者 | Yeshaya, N, Fass, D. | | 登録日 | 2023-08-27 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Sci., 33, 2024
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8TZG
 | | Structure of C-terminal LRRK2 bound to MLi-2 (I2020T mutant) | | 分子名称: | (2~{R},6~{S})-2,6-dimethyl-4-[6-[5-(1-methylcyclopropyl)oxy-1~{H}-indazol-3-yl]pyrimidin-4-yl]morpholine, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, ... | | 著者 | Sanz-Murillo, M, Villagran-Suarez, A, Alegrio Louro, J, Leschziner, A. | | 登録日 | 2023-08-26 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures.
Sci Adv, 9, 2023
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8TZE
 | | Structure of C-terminal half of LRRK2 bound to GZD-824 | | 分子名称: | 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide, Leucine-rich repeat serine/threonine-protein kinase 2 | | 著者 | Villagran-Suarez, A, Sanz-Murillo, M, Alegrio-Louro, J, Leschziner, A. | | 登録日 | 2023-08-26 | | 公開日 | 2023-12-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures.
Sci Adv, 9, 2023
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