PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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7OA6	Pseudo-atomic model for Hsp26 residues 63 to 214. Please be advised that the target map is not of sufficient resolution to unambiguously position backbone or side chain atoms. This model represents a likely fit. 分子名称: Heat shock protein 26 著者 Muehlhofer, M, Peters, C, Kriehuber, T, Kreuzeder, M, Kazman, P, Rodina, N, Reif, B, Haslbeck, M, Weinkauf, S, Buchner, J. 登録日 2021-04-19 公開日 2021-11-24 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Phosphorylation activates the yeast small heat shock protein Hsp26 by weakening domain contacts in the oligomer ensemble. Nat Commun, 12, 2021
6WBS	Human CFTR first nucleotide binding domain with dF508/V510D 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION 著者 Simon, K.S, Kothe, M, Hilbert, B, Batchelor, J.D, Hurlbut, G.D. 登録日 2020-03-27 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.857 Å) 主引用文献 Determining the Molecular Mechanism of Suppressor Mutation V510D and the Contribution of Helical Unraveling to the dF508-CFTR Defect To Be Published
7O7I	Crystal structure of the human HIPK3 kinase domain 分子名称: 1,2-ETHANEDIOL, Homeodomain-interacting protein kinase 3 著者 Kaltheuner, I.H, Anand, K, Geyer, M. 登録日 2021-04-13 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. Nat Commun, 12, 2021
7O7J	Crystal structure of the human HIPK3 kinase domain bound to abemaciclib 分子名称: Homeodomain-interacting protein kinase 3, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine 著者 Kaltheuner, I.H, Anand, K, Geyer, M. 登録日 2021-04-13 公開日 2021-11-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. Nat Commun, 12, 2021
6VTX	Crystal structure of human KLF4 zinc finger DNA binding domain in complex with NANOG DNA 分子名称: DNA (5'-D(*AP*GP*GP*GP*GP*GP*TP*GP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*CP*AP*CP*CP*CP*CP*CP*T)-3'), Krueppel-like factor 4, ... 著者 Sharma, R, Sharma, S, Choi, K.J, Ferreon, A.C.M, Ferreon, J.C, Sankaran, B, MacKenzie, K.R, Kim, C. 登録日 2020-02-13 公開日 2021-09-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nat Commun, 12, 2021
7NZC	First SH3 domain of POSH (Plenty of SH3 Domains protein) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1 著者 Palencia, A, Bessa, L.M, Jensen, M.R. 登録日 2021-03-23 公開日 2021-12-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.111 Å) 主引用文献 Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
7NRB	Re-refinement of MK3-inhibitor complex 分子名称: 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP kinase-activated protein kinase 3 著者 Croll, T.I, Read, R.J. 登録日 2021-03-03 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Adaptive Cartesian and torsional restraints for interactive model rebuilding. Acta Crystallogr D Struct Biol, 77, 2021
6VK2	NMR solution structure of Grb2-SH2 domain at pH 7 分子名称: Growth factor receptor-bound protein 2 著者 Sanches, K, Caruso, I.P, Melo, F.A, Almeida, F.C.L. 登録日 2020-01-18 公開日 2020-07-29 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The dynamics of free and phosphopeptide-bound Grb2-SH2 reveals two dynamically independent subdomains and an encounter complex with fuzzy interactions. Sci Rep, 10, 2020
7NUY	New polymorhp of proteinase K obtained by free interface diffusion technique 分子名称: Proteinase K, SULFATE ION 著者 Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R. 登録日 2021-03-15 公開日 2022-01-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form Crystals, 2021
6WE6	Camphor bound P450cam D251E structure 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Amaya, J.A, Poulos, T.L, Batabyal, D. 登録日 2020-04-01 公開日 2020-07-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Proton Relay Network in the Bacterial P450s: CYP101A1 and CYP101D1. Biochemistry, 59, 2020
7OGC	GTPase HRAS under 650 MPa pressure 分子名称: GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... 著者 Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
7OGA	GTPase HRAS under 200 MPa pressure 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N.C, Kalbitzer, H.R, Girard, E, Prange, T. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
7OGD	GTPase HRAS mutant D33K under ambient pressure 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
6WLX	PAK4 kinase domain in complex with beta-catenin Ser675 substrate peptide 分子名称: Catenin beta-1, Serine/threonine-protein kinase PAK 4 著者 Chetty, A.K, Ha, B.H, Boggon, T.J. 登録日 2020-04-20 公開日 2020-06-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of physiological phosphorylation sites by p21-activated kinase 4. J.Struct.Biol., 211, 2020
7NUZ	Proteinase K structure at atomic resolution from crystals grown in agarose gel 分子名称: GLYCEROL, MAGNESIUM ION, NITRATE ION, ... 著者 Gavira, J.A, Artusio, F, Castellvi, A, Pisano, R. 登録日 2021-03-15 公開日 2022-01-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Tuning Transport Phenomena in Agarose Gels for the Control of Protein Nucleation Density and Crystal Form Crystals, 2021
6WNY	Crystal structure of BACE1 in complex with (Z)-fluoro-olefin containing compound 15 分子名称: 6-[(Z)-2-{3-[(1S,5S,6S)-3-amino-5-methyl-1-(morpholine-4-carbonyl)-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl}-1-fluoroethenyl]pyridine-3-carbonitrile, Beta-secretase 1, IODIDE ION 著者 Whittington, D.A. 登録日 2020-04-23 公開日 2020-06-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement. Bioorg.Med.Chem.Lett., 30, 2020
7NRY	Re-refinement of MAPKAP kinase-2/inhibitor complex 3fyj 分子名称: (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, CHLORIDE ION, MALONIC ACID, ... 著者 Croll, T.I, Read, R.J. 登録日 2021-03-04 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Adaptive Cartesian and torsional restraints for interactive model rebuilding. Acta Crystallogr D Struct Biol, 77, 2021
7OG9	GTPase HRAS under ambient pressure 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
7OGB	GTPase HRAS under 500 MPa pressure 分子名称: GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... 著者 Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
7OGF	GTPase HRAS mutant D33K under 900 MPa pressure 分子名称: GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... 著者 Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
7OGE	GTPase HRAS mutant D33K under 200 MPa pressure 分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. 登録日 2021-05-06 公開日 2022-02-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
6X0B	Crystal Structure of Thioredoxin NaTrxh from Nicotiana alata 分子名称: 1,2-ETHANEDIOL, Thioredoxin H 著者 Gonzalez-Segura, L, Torres-Rodriguez, M.D, Cruz-Garcia, F. 登録日 2020-05-15 公開日 2020-07-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 High resolution crystal structure of NaTrxh from Nicotiana alata and its interaction with the S-RNase. J.Struct.Biol., 212, 2020
6WK3	Engineered carbene transferase RmaNOD Q52V, putative nitric oxide dioxygenase from Rhodothermus marinus 分子名称: ACETATE ION, COPPER (II) ION, Nitric oxide dioxygenase, ... 著者 Knight, A.M, Arnold, F.H. 登録日 2020-04-15 公開日 2020-07-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Diversity-Oriented Enzymatic Synthesis of Cyclopropane Building Blocks. Acs Catalysis, 10, 2020
7O2O	Lysozyme structure from microfluidic-based in situ data collection 分子名称: 1,2-ETHANEDIOL, Lysozyme C, SODIUM ION 著者 Gardais, A, Chavas, L. 登録日 2021-03-31 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.833 Å) 主引用文献 Manufacturing of Ultra-Thin X-ray-Compatible COC Microfluidic Devices for Optimal In Situ Macromolecular Crystallography Experiments. Micromachines (Basel), 13, 2022
6WNF	The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII 分子名称: ACETATE ION, GLYCEROL, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-04-22 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020

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